• Thumbnail for Neofunctionalization
    structure or substrate and ligand affinity, as a result of neofunctionalization. Neofunctionalization is also commonly referred to as "mutation during non-functionality"...
    13 KB (1,427 words) - 19:18, 7 February 2025
  • is another contributing factor for survival and rapid adaptation/neofunctionalization of duplicate genes. Thus, a link seems to exist between gene regulation...
    34 KB (3,683 words) - 00:52, 1 June 2025
  • subject to neofunctionalization, the process in which a duplicated gene obtains a novel function. Polyploidy Paleopolyploidy Neofunctionalization Conant,...
    8 KB (1,006 words) - 08:48, 20 April 2024
  • Thumbnail for Horseshoe crab
    many of the duplicated genes have changed through processes of neofunctionalization or subfunctionalization, meaning their functions are different from...
    80 KB (8,079 words) - 11:44, 22 June 2025
  • that try to explain the mechanisms leading to divergence: The term neofunctionalization was first coined by Force et al. 1999, but it refers to the general...
    13 KB (1,822 words) - 15:00, 2 July 2023
  • Thumbnail for Goldfish
    al. Extreme anoxia tolerance in crucian carp and goldfish through neofunctionalization of duplicated genes creating a new ethanol-producing pyruvate decarboxylase...
    53 KB (4,919 words) - 07:33, 30 June 2025
  • Thumbnail for Rattlesnake
    and gene loss events. The duplication events provided material for neofunctionalization to create the novel toxin genes, while gene loss influenced speciation...
    62 KB (7,280 words) - 17:53, 3 May 2025
  • Thumbnail for TRPA (ion channel)
    sensing in Drosophila melanogaster, and the honey bee HsTRPA underwent neofunctionalization following its divergence from waterwitch, gaining function as a high-temperature...
    8 KB (809 words) - 19:42, 27 May 2025
  • Thumbnail for Unequal crossing over
    product, then the duplicate may be retained as a redundant copy. Neofunctionalization is also a possibility: the duplicated copy acquires a mutation that...
    7 KB (877 words) - 05:15, 23 September 2021
  • Thumbnail for Gene redundancy
    functional divergence in genes are nonfunctionalization (or gene loss), neofunctionalization and subfunctionalization. During nonfunctionalization, or degeneration/gene...
    22 KB (2,837 words) - 14:30, 23 May 2025
  • Thumbnail for Cucurbita
    Rates of Protein-Coding Gene and Long Noncoding RNA Turnover and Neofunctionalization within Cucurbita". Molecular Plant. 12 (4): 506–520. doi:10.1016/j...
    121 KB (10,885 words) - 21:04, 28 June 2025
  • Thumbnail for Vertebrate visual opsin
    according to the cladogram to the right; this serves as an example of neofunctionalization. Each class has since evolved into numerous variants. Evolutionary...
    10 KB (1,049 words) - 20:10, 23 May 2025
  • Thumbnail for Homeobox
    a single ANTP-class homeobox gene. Gene duplication followed by neofunctionalization is responsible for the many homeobox genes found in eukaryotes. Comparison...
    41 KB (4,386 words) - 22:42, 24 May 2025
  • Thumbnail for Sequence homology
    include CHDW and CHDZ in birds. Deep homology EggNOG (database) Neofunctionalization OrthoDB Orthologous MAtrix (OMA) PhEVER Protein family Protein superfamily...
    41 KB (4,481 words) - 18:11, 24 June 2025
  • Thumbnail for Sodium–potassium pump
    of ATPα2 has also been noted in other insects. Duplications and neofunctionalization of ATPα1 have been observed in insects that are adapted to cardiotonic...
    38 KB (4,375 words) - 04:05, 20 June 2025
  • Thumbnail for Electric organ (fish)
    whole-genome duplication event in the teleost lineage allowed for the neofunctionalization of the voltage-gated sodium channel gene Scn4aa which produces electric...
    25 KB (2,344 words) - 13:53, 28 May 2025
  • Thumbnail for Snake venom
    VJ (January 2007). "Inventing an arsenal: adaptive evolution and neofunctionalization of snake venom phospholipase A2 genes". BMC Evolutionary Biology...
    68 KB (7,794 words) - 14:58, 9 June 2025
  • Thumbnail for Evolution of snake venom
    to extant species Domain loss has also been implicated in venom neofunctionalization. Investigation of the evolutionary history of viperid SVMP venom...
    54 KB (6,426 words) - 03:51, 2 June 2025
  • Thumbnail for Subfunctionalization
    independently mutable regions and possessed the ability to subfunctionalize. Neofunctionalization, where one paralogous copy derives a new function after gene duplication...
    15 KB (1,756 words) - 00:45, 26 May 2025
  • Rates of Protein-Coding Gene and Long Noncoding RNA Turnover and Neofunctionalization within Cucurbita". Molecular Plant. 12 (4): 506–520. Bibcode:2019MPlan...
    174 KB (10,444 words) - 03:30, 9 June 2025
  • (September 2010). "Honey bee thermal/chemical sensor, AmHsTRPA, reveals neofunctionalization and loss of transient receptor potential channel genes". The Journal...
    50 KB (5,540 words) - 19:53, 9 June 2025
  • where a paralog specializes one of several ancestral functions, or neofunctionalization, where a totally new functional capability evolves. It is thought...
    6 KB (614 words) - 16:02, 18 April 2025
  • diversity can occur in a variety of ways, including gene duplication and neofunctionalization, gene insertion, as well as alternative splicing. PRRs may evolve...
    49 KB (5,846 words) - 06:49, 2 June 2025
  • Thumbnail for De novo gene birth
    Chen L (December 2010). "Evolution of an antifreeze protein by neofunctionalization under escape from adaptive conflict". Proceedings of the National...
    129 KB (13,589 words) - 00:21, 1 June 2025
  • Thumbnail for Cucurbita argyrosperma
    Rates of Protein-Coding Gene and Long Noncoding RNA Turnover and Neofunctionalization within Cucurbita". Molecular Plant. 12 (4): 506–520. doi:10.1016/j...
    28 KB (2,850 words) - 17:33, 25 May 2025
  • Thumbnail for Lycodichthys
    the antifreeze protein in L. dearborni provides a prime example of neofunctionalization after gene duplication. In the case of the Antarctic zoarcid fish...
    6 KB (724 words) - 17:35, 16 November 2024
  • Thumbnail for Distyly
    (2020-09-15). "Supergene evolution via stepwise duplications and neofunctionalization of a floral-organ identity gene". Proceedings of the National Academy...
    28 KB (3,052 words) - 17:21, 23 May 2025
  • genes can then be co-opted by natural selection by a process called neofunctionalization. In other instances constructive neutral evolution does not promote...
    32 KB (3,735 words) - 16:50, 23 May 2025
  • Such intense genomic events lead to gene sub-functionalization, neofunctionalization or in many cases lead to loss of functions. Ohno, 40 years ago proposed...
    24 KB (2,961 words) - 23:06, 22 March 2025
  • Thumbnail for Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
    in bundle-sheath cells, and within the coding region, generating neofunctionalization. Selection for CO2 preservation function as well as enhanced water...
    17 KB (1,892 words) - 10:55, 24 June 2025