• Thumbnail for Nitric oxide synthase
    Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling...
    31 KB (3,605 words) - 22:52, 4 March 2025
  • Thumbnail for Endothelial NOS
    Endothelial NOS (eNOS), also known as nitric oxide synthase 3 (NOS3) or constitutive NOS (cNOS), is an enzyme that in humans is encoded by the NOS3 gene...
    33 KB (4,002 words) - 06:04, 3 June 2024
  • calcium-calmodulin and other cofactors. Nitric oxide synthases (NOSs) synthesize the metastable free radical nitric oxide (NO). Three isoforms are known for...
    70 KB (7,676 words) - 21:55, 7 May 2025
  • Thumbnail for Exhaled nitric oxide
    role remains unclear. In humans, nitric oxide is produced from L-arginine by three enzymes called nitric oxide synthases (NOS): inducible (iNOS), endothelial...
    24 KB (2,686 words) - 12:11, 17 March 2025
  • Thumbnail for Nitric oxide synthase 2 (inducible)
    Nitric oxide synthase, inducible is an enzyme which is encoded by the NOS2 gene in humans and mice. Three related pseudogenes are located within the Smith-Magenis...
    5 KB (600 words) - 05:51, 5 September 2024
  • Thumbnail for Nitric oxide
    Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO. It is one of the principal oxides of nitrogen. Nitric oxide...
    32 KB (3,139 words) - 14:24, 6 May 2025
  • nitric-oxide synthase (flavodoxin) (EC 1.14.14.47, nitric oxide synthetase, NO synthase) is an enzyme with systematic name L-arginine,reduced flavodoxin:oxygen...
    3 KB (364 words) - 02:57, 5 March 2025
  • cells. NO is biosynthesized endogenously from L-arginine by various nitric oxide synthase (NOS) enzymes. Reduction of inorganic nitrate may also serve to...
    41 KB (4,819 words) - 19:42, 14 January 2025
  • Thumbnail for Tetrahydrobiopterin
    (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases. Chemically, its structure is that of a (dihydropteridine...
    31 KB (2,818 words) - 02:10, 12 May 2025
  • Thumbnail for Hemoprotein
    (July 2021). "The Relationship between Myoglobin, Aerobic Capacity, Nitric Oxide Synthase Activity and Mitochondrial Function in Fish Hearts". Antioxidants...
    22 KB (2,454 words) - 20:34, 5 March 2025
  • Thumbnail for Endothelial dysfunction
    cardiovascular events. Atherosclerosis Endothelial activation Nitric oxide endothelial nitric oxide synthase Prostacyclin Endothelium-derived relaxing factor Endothelin...
    19 KB (1,970 words) - 17:52, 11 October 2024
  • Thumbnail for Citrulline
    of nitric oxide from the amino acid arginine, catalyzed by nitric oxide synthase. Citrulline can be derived from: from arginine via nitric oxide synthase...
    12 KB (1,049 words) - 01:25, 26 April 2025
  • Thumbnail for Reactive nitrogen species
    molecules derived from nitric oxide (•NO) and superoxide (O2•−) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH...
    7 KB (787 words) - 06:24, 27 January 2024
  • Thumbnail for Louis Ignarro
    American pharmacologist. For demonstrating the signaling properties of nitric oxide, he was co-recipient of the 1998 Nobel Prize in Physiology or Medicine...
    23 KB (2,739 words) - 03:08, 2 April 2025
  • Thumbnail for Saliva testing
    Cardio-protective nitric oxide is generated in the body by a family of specific enzymes, nitric oxide synthase. An alternative pathway for the generation of nitric oxide...
    69 KB (8,483 words) - 06:08, 14 February 2025
  • Thumbnail for Heme
    (including metabolism of some drugs), gas sensing (guanyl cyclases, nitric oxide synthase), and microRNA processing (DGCR8). Heme is a coordination complex...
    42 KB (4,397 words) - 02:54, 22 March 2025
  • Thumbnail for Argininosuccinate synthase
    while citrulline up-regulates it. The enzyme endothelial nitric oxide synthase produces nitric oxide from arginine in endothelial cells. Argininosuccinate...
    16 KB (1,737 words) - 04:49, 4 June 2024
  • their relaxative effects on vasculature is by promoting endothelial nitric oxide synthase (eNOS) activity and NO bioavailability. This is believed to be the...
    21 KB (2,189 words) - 17:05, 23 April 2025
  • Thumbnail for NOS1
    NOS1 (redirect from Nitric oxide synthase 1)
    Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene. Nitric oxide synthases (EC 1.14.13.39)...
    9 KB (1,022 words) - 22:37, 22 December 2023
  • Thumbnail for Nitric oxide dioxygenase
    Nitric oxide dioxygenase (EC 1.14.12.17) is an enzyme that catalyzes the conversion of nitric oxide (NO) to nitrate (NO− 3) . The net reaction for the...
    20 KB (2,188 words) - 04:10, 17 September 2023
  • and translationally blocks the gene expression of human inducible nitric oxide synthase (hiNOS) by binding to its 3'UTR. There is dual regulation of hiNOS...
    3 KB (299 words) - 11:40, 10 September 2021
  • Thumbnail for 7-Nitroindazole
    neuronal nitric oxide synthase, a hemoprotein enzyme that, in neuronal tissue, converts arginine to citrulline and nitric oxide (NO). Nitric oxide can diffuse...
    6 KB (577 words) - 15:30, 23 December 2024
  • Thumbnail for Spermidine
    N-methyl-D-aspartate receptor (NMDA receptor), which has been associated with nitric oxide synthase (NOS) and cGMP/PKG pathway activation and a decrease of Na+,K+-ATPase...
    17 KB (1,425 words) - 08:07, 20 May 2025
  • Thumbnail for Imidazole
    imidazoles, including clotrimazole, are selective inhibitors of nitric oxide synthase. Other biological activities of the imidazole pharmacophore relate...
    27 KB (2,716 words) - 04:50, 5 February 2025
  • Thumbnail for Spilanthol
    mechanism involves inhibition of nitric oxide production due to reduced expression of inducible nitric oxide synthase enzyme (iNOS) in macrophages. Transcription...
    5 KB (454 words) - 15:39, 7 August 2024
  • Thumbnail for Zusanli
    by nitric oxide as well, through the upregulation of inducible nitric oxide synthase (iNOS), an increase in endogenous opiates, muscarinic cholinergic...
    5 KB (588 words) - 04:24, 3 January 2025
  • Thumbnail for Minoxidil
    Minoxidil (category Amine oxides)
    cofactor for nitric oxide synthase. Minoxidil stimulates prostaglandin E2 production by activating COX-1 and prostaglandin endoperoxide synthase-1 but inhibits...
    48 KB (4,602 words) - 19:10, 22 May 2025
  • Thumbnail for Tension headache
    contributes to the process of central sensitization. Briefly, the enzyme nitric oxide synthase (NOS) forms NO which ultimately results in vasodilatation and activation...
    33 KB (3,325 words) - 15:02, 9 March 2025
  • Thumbnail for Nitrovasodilator
    of nitric oxide (NO), and is mostly used for the treatment and prevention of angina pectoris. This group of drugs includes nitrates (esters of nitric acid)...
    12 KB (1,273 words) - 15:29, 3 January 2025
  • Thumbnail for Palmar erythema
    H, Fandino J, Fathi AR (2015). "Estrogen Induces Nitric Oxide Production Via Nitric Oxide Synthase Activation in Endothelial Cells". Neurovascular Events...
    3 KB (291 words) - 21:05, 24 July 2024