• Nucleic acid methods are the techniques used to study nucleic acids: DNA and RNA. DNA extraction Phenol–chloroform extraction Minicolumn purification...
    4 KB (378 words) - 02:12, 10 June 2025
  • Thumbnail for Nucleic acid
    Nucleic acids are large biomolecules that are crucial in all cells and viruses. They are composed of nucleotides, which are the monomer components: a...
    24 KB (2,848 words) - 18:30, 3 April 2025
  • Thumbnail for Nucleic acid quantitation
    In molecular biology, quantitation of nucleic acids is commonly performed to determine the average concentrations of DNA or RNA present in a mixture,...
    15 KB (1,752 words) - 04:03, 18 February 2025
  • The nucleic acid notation currently in use was first formalized by the International Union of Pure and Applied Chemistry (IUPAC) in 1970. This universally...
    14 KB (1,418 words) - 21:05, 11 December 2023
  • Thumbnail for Nucleic acid sequence
    A nucleic acid sequence is a succession of bases within the nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. This succession...
    22 KB (2,409 words) - 19:05, 21 May 2025
  • Thumbnail for Nucleic acid structure
    Nucleic acid structure refers to the structure of nucleic acids such as DNA and RNA. Chemically speaking, DNA and RNA are very similar. Nucleic acid structure...
    18 KB (2,416 words) - 16:16, 5 December 2024
  • Thumbnail for Nucleic acid secondary structure
    Nucleic acid secondary structure is the basepairing interactions within a single nucleic acid polymer or between two polymers. It can be represented as...
    18 KB (2,194 words) - 22:57, 24 February 2025
  • Thumbnail for Nucleic acid analogue
    nucleic acids include peptide nucleic acids (PNA), morpholino, and locked nucleic acids (LNA), as well as glycol nucleic acids (GNA), threose nucleic...
    49 KB (5,299 words) - 16:59, 25 May 2025
  • Thumbnail for Spin column-based nucleic acid purification
    column-based nucleic acid purification is a solid phase extraction method to quickly purify nucleic acids. This method relies on the fact that nucleic acid will...
    5 KB (639 words) - 17:54, 14 November 2024
  • Thumbnail for RNA
    RNA (redirect from RiboNucleic Acid)
    proteins (messenger RNA). RNA and deoxyribonucleic acid (DNA) are nucleic acids. The nucleic acids constitute one of the four major macromolecules essential...
    66 KB (7,664 words) - 19:12, 3 June 2025
  • Thumbnail for Peptide nucleic acid
    Peptide nucleic acid (PNA) is an artificially synthesized polymer similar to DNA or RNA. Synthetic peptide nucleic acid oligomers have been used in recent...
    15 KB (1,831 words) - 11:40, 25 May 2025
  • Nucleic acid thermodynamics is the study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA). The melting temperature...
    24 KB (2,923 words) - 02:42, 25 January 2025
  • Thumbnail for Xeno nucleic acid
    Xenonucleic acids (XNAs) are synthetic nucleic acid analogues that are engineered with structurally distinct components, such as alternative nucleosides...
    22 KB (2,634 words) - 09:54, 1 June 2025
  • Thumbnail for DNA
    DNA (redirect from Deoxiribose nucleic acid)
    and ribonucleic acid (RNA) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four...
    167 KB (17,915 words) - 22:22, 29 May 2025
  • Thumbnail for Denaturation (biochemistry)
    secondary, and/or tertiary, and/or quaternary structures of proteins or nucleic acids resulting in a loss of bioactivity. Note 1: Modified from the definition...
    32 KB (3,189 words) - 09:12, 27 May 2025
  • structure of nucleic acids, such as RNA and DNA, can be largely classified into biophysical and biochemical methods. Biophysical methods use the fundamental...
    35 KB (4,459 words) - 01:21, 3 December 2024
  • Thumbnail for Locked nucleic acid
    A locked nucleic acid (LNA), also known as bridged nucleic acid (BNA), and often referred to as inaccessible RNA, is a modified RNA nucleotide in which...
    14 KB (1,647 words) - 12:24, 23 May 2025
  • Solid-phase reversible immobilization (category Nucleic acids)
    is a method of purifying nucleic acids from solution. It uses silica- or carboxyl-coated paramagnetic beads, which reversibly bind to nucleic acids in the...
    3 KB (355 words) - 16:17, 10 December 2024
  • Nucleic acid NMR is the use of nuclear magnetic resonance spectroscopy to obtain information about the structure and dynamics of nucleic acid molecules...
    15 KB (1,968 words) - 19:16, 3 June 2025
  • Thumbnail for Nucleic acid test
    A nucleic acid test (NAT) is a technique used to detect a particular nucleic acid sequence and thus usually to detect and identify a particular species...
    11 KB (1,417 words) - 20:39, 20 July 2024
  • Threose nucleic acid (TNA) is an artificial genetic polymer in which the natural five-carbon ribose sugar found in RNA has been replaced by an unnatural...
    10 KB (1,216 words) - 08:34, 7 June 2025
  • Thumbnail for Nucleic acid design
    Nucleic acid design is the process of generating a set of nucleic acid base sequences that will associate into a desired conformation. Nucleic acid design...
    19 KB (2,110 words) - 17:50, 25 March 2025
  • of nucleic acids". Annual Review of Biochemistry. 36: 407–48. doi:10.1146/annurev.bi.36.070167.002203. PMID 18257727. McClean, Phillip. "Nucleic Acid Hybridizations"...
    5 KB (564 words) - 11:50, 26 August 2024
  • method (aka Boom nucleic acid extraction method) is a solid phase extraction method for isolating nucleic acid from a biological sample. This method is...
    22 KB (2,552 words) - 16:20, 8 June 2024
  • Thumbnail for Polymerase chain reaction
    in nucleic acid tests for the diagnosis of infectious diseases. PCR amplifies a specific region of a DNA strand (the DNA target). Most PCR methods amplify...
    90 KB (11,293 words) - 13:08, 23 May 2025
  • Thumbnail for DNA nanotechnology
    design and manufacture of artificial nucleic acid structures for technological uses. In this field, nucleic acids are used as non-biological engineering...
    84 KB (9,653 words) - 02:05, 30 January 2025
  • Nucleic acid structure prediction is a computational method to determine secondary and tertiary nucleic acid structure from its sequence. Secondary structure...
    35 KB (3,715 words) - 12:11, 2 November 2024
  • Thumbnail for Acid
    acid catalysis. Many biologically important molecules are acids. Nucleic acids, which contain acidic phosphate groups, include DNA and RNA. Nucleic acids...
    47 KB (5,960 words) - 15:34, 29 May 2025
  • Nucleic acid sequence-based amplification, commonly referred to as NASBA, is a method in molecular biology which is used to produce multiple copies of...
    13 KB (1,634 words) - 00:53, 27 May 2025
  • Thumbnail for Acid guanidinium thiocyanate-phenol-chloroform extraction
    foaming and ensure deactivation of RNases. Column-based nucleic acid purification Nucleic acid methods Ethanol precipitation DNA separation by silica adsorption...
    6 KB (785 words) - 10:52, 25 January 2025