• Thumbnail for PIK3R4
    adaptor protein, or VPS15 is an enzyme that in humans is encoded by the PIK3R4 gene. GRCh38: Ensembl release 89: ENSG00000196455 – Ensembl, May 2017 GRCm38:...
    4 KB (568 words) - 23:44, 15 June 2025
  • PIK3C3 gene. In human cells Vps34 associates with a regulatory subunit, PIK3R4(p150, Vps15). Vps34 is more accurately described as a phosphatidylinositol...
    4 KB (511 words) - 11:12, 28 May 2025
  • Thumbnail for PI3K/AKT/mTOR pathway
    members including PIK3CA, PIK3CB and PIK3R4, leading to transcriptional changes in PIK3C2G, PIK3CA, PIK3CB, PIK3R4 as well as pathways associated with...
    36 KB (4,330 words) - 21:54, 29 May 2025
  • Thumbnail for Autophagy
    complex. The autophagy-inducible Beclin-1 complex contains the proteins PIK3R4(p150), Atg14L and the class III phosphatidylinositol 3-phosphate kinase...
    79 KB (9,299 words) - 18:49, 4 May 2025
  • Thumbnail for Phosphoinositide 3-kinase
    subunit 2 (beta) p85-β PIK3R3 PI3K, regulatory subunit 3 (gamma) p55-γ PIK3R4 PI3K, regulatory subunit 4 p150 PIK3R5 PI3K, regulatory subunit 5 p101 PIK3R6...
    32 KB (3,470 words) - 09:13, 9 June 2025
  • P27986 12162 PIK3R2 HGNC:8980 O00459 12163 PIK3R3 HGNC:8981 Q92569 12164 PIK3R4 HGNC:8982 Q99570 12165 PIK3R5 HGNC:30035 Q8WYR1 12166 PIK3R6 HGNC:27101...
    282 KB (17 words) - 09:28, 10 February 2025
  • Thumbnail for WD40 repeat
    NLE1, NSMAF, NUP37, NUP43, NWD1, PAAF1, PAFAH1B1, PAK1IP1, PEX7, PHIP, PIK3R4, PLAA, PLRG1, PPP2R2A, PPP2R2B, PPP2R2C, PPP2R2D, PPWD1, PREB, PRPF19, PRPF4...
    13 KB (958 words) - 04:46, 26 August 2024
  • Thumbnail for RAB7A
    RILP, as well as PSMA7, RNF115 and FYCO1. Interacts with the PIK3C3/VPS34-PIK3R4 complex. The GTP-bound form interacts with OSBPL1A and CLN3. Rab7A was also...
    18 KB (2,315 words) - 05:30, 27 May 2024
  • Thumbnail for Protein kinase domain
    PDGFRA ; PDGFRB ; PDIK1L ; PDPK1 ; PDPK2P ; PEAK1 ; PEAK3 ; PHKG1 ; PHKG2 ; PIK3R4 ; PIM1 ; PIM2 ; PIM3 ; PINK1 ; PKDCC ; PKMYT1 ; PKN1 ; PKN2 ; PKN3 ; PLK1 ;...
    17 KB (1,562 words) - 22:44, 26 May 2025
  • protein MAST1 result in mega corpus callosum syndrome, and that mutations in PIK3r4 are associated with neurodevelopmental disorders. Awards and Honours Keays...
    12 KB (1,163 words) - 08:58, 29 July 2024