Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which...
49 KB (5,846 words) - 12:19, 18 July 2025
in the host. They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. This allows...
18 KB (2,145 words) - 12:14, 18 July 2025
RIG-I (category RIG-I-like receptors)
RIG-I (retinoic acid-inducible gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response...
24 KB (2,964 words) - 09:30, 13 July 2025
on interacting with TLR5 on human T cells. TLRs are a type of pattern recognition receptor (PRR) and recognize molecules that are broadly shared by pathogens...
61 KB (6,771 words) - 19:25, 22 May 2025
receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition of...
25 KB (3,011 words) - 17:07, 24 May 2024
cells utilize specialized receptors known as Pattern Recognition Receptors(PRRs) to detect viral infection; these receptors are able to recognize pathogen-associated...
8 KB (1,059 words) - 14:12, 24 January 2024
MDA5 (category RIG-I-like receptors)
family, which also includes RIG-I and LGP2, and functions as a pattern recognition receptor capable of detecting viruses. It is generally believed that MDA5...
19 KB (2,222 words) - 17:53, 16 July 2025
EF-Tu receptor, abbreviated as EFR, is a pattern-recognition receptor (PRR) that binds to the prokaryotic protein EF-Tu (elongation factor thermo unstable)...
12 KB (1,511 words) - 12:42, 27 December 2023
through a common structural motif, RAGE is often referred to as a pattern recognition receptor. RAGE also has at least one other agonistic ligand: high mobility...
58 KB (6,883 words) - 02:35, 18 July 2025
via the phagocytic pathway. In this way, the mannose receptor acts as a pattern recognition receptor. The presence of a di-aromatic FENTLY (Phe-Glu-Asn-Thr-Leu-Tyr)...
32 KB (3,691 words) - 05:54, 2 June 2025
being activated by pattern recognition receptors (PRRs) that recognize evolutionarily conserved pathogen-associated molecular patterns (PAMPs) as infectious...
11 KB (1,153 words) - 15:53, 1 September 2024
Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family of pattern recognition receptors (PRRs) that form the cornerstone of the...
12 KB (1,372 words) - 07:28, 15 July 2025
protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified. Discovered by Tillett and Francis in...
48 KB (5,497 words) - 17:00, 16 July 2025
immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi...
15 KB (1,690 words) - 16:56, 16 July 2025
gene. TLR4 belongs to the toll-like receptor family which is representative of the pattern recognition receptors (PRR), so named for their ability to...
75 KB (9,113 words) - 21:00, 18 July 2025
promotes a noninfectious inflammatory response by binding to a pattern recognition receptor (PRR). Inflammation is a key aspect of the innate immune response;...
37 KB (3,643 words) - 04:04, 17 July 2025
by the TLR3 gene. TLR3 is a member of the toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3 recognizes double-stranded...
9 KB (1,027 words) - 18:49, 16 July 2025
the human brain Pattern recognition receptor, receptors of the innate immune system that identify pathogen-associated molecular patterns Pennsylvania Railroad...
1 KB (180 words) - 21:22, 6 July 2025
phylogenetically more highly developed. Pattern-recognition receptors (PRRs) come into play here. These are receptors that recognize the gross, primarily...
21 KB (2,370 words) - 18:49, 16 July 2025
MARCO (category Scavenger receptors)
found on particular subsets of macrophages. Scavenger receptors are pattern recognition receptors (PRRs) found most commonly on immune cells. Their defining...
21 KB (2,234 words) - 04:26, 15 July 2025
CD14 was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection...
7 KB (849 words) - 07:02, 15 July 2025
mast cells. These cells present receptors contained on the surface or within the cell, named pattern recognition receptors (PRRs), which recognize molecules...
44 KB (4,847 words) - 17:37, 16 July 2025
neuroscience, pattern recognition is a cognitive process that matches information from a stimulus with information retrieved from memory. Pattern recognition occurs...
35 KB (4,555 words) - 09:26, 14 July 2025
immunoglobulin E receptors (e.g., FcεRI), physical injury through pattern recognition receptors for damage-associated molecular patterns (DAMPs), microbial...
55 KB (6,212 words) - 18:37, 10 July 2025
genomes. The CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in...
11 KB (1,393 words) - 18:39, 23 February 2024
NOD2 (category NOD-like receptors)
and stimulates an immune reaction. NOD2 is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants...
13 KB (1,533 words) - 17:38, 17 July 2025
R gene (section Pattern recognition receptors (PRRs))
essential for pathogen defense are pattern recognition receptors (PRRs), wall associated kinase (WAKs), receptors with nucleotide-binding domain (NLRs)...
18 KB (2,099 words) - 18:35, 12 August 2024
Immune system (redirect from Immune recognition)
response is usually triggered when microbes are identified by pattern recognition receptors, which recognize components that are conserved among broad groups...
119 KB (13,589 words) - 18:30, 24 July 2025
receptors in the immune system are pattern recognition receptors (PRRs), Toll-like receptors (TLRs), killer activated and killer inhibitor receptors (KARs...
2 KB (113 words) - 22:22, 12 July 2023
immunoglobulin-like receptors Major histocompatibility complex (MHC) NOD-like receptors Pattern recognition receptor Toll-like receptors RIG-I like receptors Dynein...
3 KB (275 words) - 18:18, 23 June 2025