Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 15:04, 24 May 2025
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
13 KB (1,563 words) - 09:00, 13 March 2024
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
29 KB (3,358 words) - 18:48, 22 June 2025
eosinophil such as those caused by Platelet-derived growth factor receptor A or platelet-derived growth factor receptor B fusion genes, the myelodysplasia...
44 KB (5,003 words) - 14:24, 24 February 2025
PDGFA (redirect from Platelet-derived growth factor subunit A)
Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene. The protein encoded by this gene is a member of the...
8 KB (1,108 words) - 23:22, 16 March 2025
Brain-derived neurotrophic factor (BDNF) Nerve growth factor (NGF) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Placental growth factor (PGF) Platelet-derived...
10 KB (1,131 words) - 18:45, 6 May 2025
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 01:06, 1 March 2025
PDGFRB (category Tyrosine kinase receptors)
Platelet-derived growth factor receptor beta is a protein that in humans is encoded by the PDGFRB gene. Mutations in PDGFRB are mainly associated with...
31 KB (3,403 words) - 06:55, 9 June 2025
fibronectin, platelet-derived growth factor, and chemotactic agents. Delta granules, or dense bodies, contain ADP, calcium, and serotonin, which are platelet-activating...
71 KB (8,529 words) - 20:44, 19 June 2025
"trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor". Cell. 65 (5): 885–893. doi:10...
50 KB (5,881 words) - 13:31, 5 May 2025
endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth factor (PDGF)/vascular...
24 KB (3,053 words) - 21:44, 26 May 2025
targeting vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Ofev was developed by Boehringer...
36 KB (3,141 words) - 01:15, 30 June 2025
PDGFB (redirect from Platelet-derived growth factor beta polypeptide)
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the...
3 KB (434 words) - 00:28, 5 October 2022
protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis...
10 KB (1,256 words) - 19:44, 18 June 2025
cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by platelets, and mesenchymal cells and acts as a multi-functional...
23 KB (2,623 words) - 08:53, 15 March 2025
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,716 words) - 11:48, 25 May 2025
maturation factor, insulin, insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), platelet-derived growth...
16 KB (1,784 words) - 04:08, 6 January 2024
VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
8 KB (758 words) - 08:47, 24 June 2025
is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
34 KB (4,517 words) - 04:19, 9 June 2025
metastatic gastrointestinal stromal tumor (GIST) that harbor a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation. Avapritinib is a kinase...
16 KB (1,218 words) - 20:03, 29 May 2025
Schering and Novartis. It inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2...
7 KB (564 words) - 16:04, 9 January 2024
GRB2 (redirect from Growth factor receptor-bound protein 2)
Growth factor receptor-bound protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2...
82 KB (9,401 words) - 09:01, 24 June 2025
kinases and examples of these are platelet derived growth factor receptor (PDGFR) pathway and epidermal growth factor receptor (EGFR). Src contains at least...
21 KB (2,648 words) - 12:12, 26 July 2024
specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins...
40 KB (4,578 words) - 12:30, 10 September 2024
Imatinib (category Non-receptor tyrosine kinase inhibitors)
myelodysplastic/myeloproliferative diseases associated with platelet-derived growth factor receptor gene rearrangements, aggressive systemic mastocytosis without...
72 KB (6,714 words) - 21:08, 29 May 2025
Nerve Growth Factor-inducible, a protein whose expression is induced by NGF Neurotrophin Nerve growth factor receptor Growth factor Brain-derived neurotrophic...
27 KB (3,118 words) - 10:07, 24 June 2025
this is no longer recommended. Factor VII has been shown to interact with tissue factor and endothelial protein C receptor. GRCh38: Ensembl release 89:...
12 KB (1,376 words) - 17:01, 10 May 2024
Stuart; Mackey, David A. (2013). "Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern...
40 KB (4,315 words) - 01:39, 4 July 2025
Tamura T (March 2000). "Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop"...
30 KB (3,504 words) - 03:59, 7 April 2025
Adiponectin (category Adiponectin receptor agonists)
binds to a number of receptors. So far, two receptors have been identified with homology to G protein-coupled receptors, and one receptor similar to the cadherin...
33 KB (3,602 words) - 02:52, 5 June 2025