• Polycomb repressive complex 1 (PRC1) is one of the two classes of Polycomb Repressive complexes, the other being PRC2. Polycomb-group proteins play a...
    2 KB (207 words) - 15:01, 20 November 2023
  • PRC2 (polycomb repressive complex 2) is one of the two classes of polycomb-group proteins or (PcG). The other component of this group of proteins is PRC1...
    5 KB (558 words) - 06:51, 4 January 2024
  • processes. Polycomb Gene complexes or PcG silencing consist of at least three kinds of multiprotein complex Polycomb Repressive Complex 1 (PRC1), PRC2...
    13 KB (1,435 words) - 09:07, 17 May 2024
  • SUZ12 polycomb repressive complex 2 subunit pseudogene 1 is a pseudogene. "Human PubMed Reference:". National Center for Biotechnology Information, U.S...
    830 bytes (92 words) - 19:26, 31 July 2024
  • Thumbnail for PCGF1
    PCGF1 gene. PCGF1 is a component defining the non-canonical polycomb repressive complex 1.1 (ncPRC1) interacting with RING1A/B, RYBP, BCOR and KDM2B. PCGF1-BCOR...
    8 KB (854 words) - 02:02, 3 December 2023
  • Thumbnail for CDKN2BAS
    to chromobox 7 (CBX7) within the polycomb repressive complex 1 and to SUZ12, a component of polycomb repression complex 2 and through these interactions...
    13 KB (1,125 words) - 16:17, 13 October 2024
  • Thumbnail for Silencer (genetics)
    stem cells, especially in hematopoietic stem cells. The Polycomb Repressive Complex 1 (PRC 1) is directly involved in the process of hematopoiesis, and...
    27 KB (3,340 words) - 19:51, 25 May 2025
  • Thumbnail for KDM2B
    binding domain. KDM2B consequently recruits the non-canonical polycomb repressive complex 1.1 (ncPRC1) to unmethylated CpG islands via a direct interaction...
    12 KB (1,477 words) - 02:09, 1 December 2023
  • Thumbnail for XIST
    involved in the repression of Xist expression. Polycomb repressive complex 2 (PRC2) consist of a class of polycomb group proteins that are involved in catalyzing...
    34 KB (4,242 words) - 14:36, 11 March 2025
  • Thumbnail for Polycomb recruitment in X chromosome inactivation
    periphery. and recruits repressive chromatin-remodelling complexes Among these, Xist recruits proteins of the Polycomb repressive complexes. Whether Xist directly...
    14 KB (1,609 words) - 13:32, 4 August 2024
  • Thumbnail for WD repeat domain 18
    of the rixosome by the Polycomb Repressive Complex 1 has been proposed to lead to its functioning in establishing repressive chromatin structures by...
    2 KB (335 words) - 00:11, 30 November 2023
  • Thumbnail for EZH2
    EZH2 (category EC 2.1.1)
    cell mitosis. EZH2 is the functional enzymatic component of the Polycomb Repressive Complex 2 (PRC2), which is responsible for healthy embryonic development...
    51 KB (5,393 words) - 20:48, 29 May 2025
  • methyltransferases EZH2 and EZH1, which are key components of the polycomb repressive complex 2 (PRC2). PRC2 plays a critical role in gene silencing and is...
    13 KB (737 words) - 05:16, 2 July 2025
  • regulated. Because Polycomb repressive complex 1 (PRC1) contains a number of proteins that work together to repress SWI/SNF complex chromatin remodeling...
    23 KB (2,269 words) - 21:58, 22 May 2025
  • Thumbnail for L3MBTL2
    Ogawa H, Ishiguro K, Gaubatz S, Livingston DM, Nakatani Y (May 2002). "A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in...
    4 KB (614 words) - 00:00, 3 December 2023
  • 2010). "Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance". Proc. Natl. Acad. Sci. U.S.A. 107 (1): 169–74...
    8 KB (853 words) - 08:37, 13 April 2024
  • Thumbnail for BMI1
    BMI1 (redirect from Bmi-1)
    Polycomb complex protein BMI-1 also known as polycomb group RING finger protein 4 (PCGF4) or RING finger protein 51 (RNF51) is a protein that in humans...
    21 KB (2,644 words) - 12:23, 24 June 2024
  • Thumbnail for Cellular differentiation
    differentiation. In the realm of gene silencing, Polycomb repressive complex 2, one of two classes of the Polycomb group (PcG) family of proteins, catalyzes...
    53 KB (6,220 words) - 15:29, 16 June 2025
  • an Australian singer, songwriter, and internet personality Polycomb repressive complex 2 or PRC2, a protein AN/PRC, for "Army/Navy, Portable, Radio...
    3 KB (353 words) - 18:19, 2 June 2025
  • occurs through polycomb mediated gene silencing via histone methylation and chromodomain interactions. A polycomb repressive complex (PRC); PRC2, mediates...
    28 KB (2,633 words) - 00:40, 13 February 2025
  • Thumbnail for FENDRR
    transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters...
    1 KB (169 words) - 06:03, 6 December 2022
  • Polycomb-group proteins and non-coding genes such as Xist. The mechanism for such spreading is still a matter of controversy. The polycomb repressive...
    20 KB (2,188 words) - 11:59, 16 July 2025
  • Thumbnail for SUZ12
    of this gene has not yet been determined. SUZ12, as part of Polycomb Repressive Complex 2 (PRC2), may be involved with chromatin silencing in conjunction...
    10 KB (1,230 words) - 09:40, 2 March 2025
  • the displacement of the SWI/SNF complex component BRG1 and RUNX1 mediated recruitment of polycomb-repressive complex 1 (PRC1) component RING1B at the three...
    26 KB (2,849 words) - 19:45, 14 June 2025
  • Thumbnail for USP7
    interact with Ataxin 1, CLSPN, P53, and more recently with MAGED1 and histone H2A through its function in the polycomb repressive complex. A proteomic screen...
    19 KB (2,280 words) - 11:05, 23 June 2025
  • Thumbnail for Vernalization
    regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION 2". Nature Communications. 9 (1): 5438. Bibcode:2018NatCo...9.5438G...
    18 KB (1,983 words) - 14:23, 24 May 2025
  • It encodes the catalytic component of the PRC2 protein complex (Polycomb Repressive Complex 2), which regulates chromatin structure and gene expression...
    11 KB (1,280 words) - 09:58, 23 November 2024
  • Thumbnail for Histone
    deposited by the polycomb complex PRC2. It is a clear marker of gene repression, and is likely bound by other proteins to exert a repressive function. Another...
    91 KB (10,379 words) - 21:47, 15 July 2025
  • or polymerase on open DNA. For example, H3K27 trimethylation by the polycomb complex PRC2 causes chromosomal compaction and gene silencing. These histone...
    61 KB (7,316 words) - 22:13, 10 April 2025
  • Thumbnail for RNF2
    RNF2 (category Genes on human chromosome 1)
    that in humans is encoded by the RNF2 gene. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression...
    8 KB (1,107 words) - 10:46, 20 January 2024