In molecular biology, prostanoids are active lipid mediators that regulate inflammatory response. Prostanoids are a subclass of eicosanoids consisting...

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for...

forming PGH2. PGH2 is the parent prostanoid to all other prostanoids. It is metabolized by (see diagram in Prostanoid): a) The prostaglandin E synthase...

but generally with lesser affinity and responsiveness to certain other prostanoids (see Prostaglandin receptors). Animal model studies have implicated EP1...

but generally with lesser affinity and responsiveness, certain other prostanoids (see Prostaglandin receptors). EP4 has been implicated in various physiological...

Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost, is a naturally occurring prostaglandin used in medicine to induce...

including a 5-carbon ring. They are a subclass of eicosanoids and of the prostanoid class of fatty acid derivatives. The structural differences between prostaglandins...

lesser extent PGE2 at concentrations close to those of PGF2α. Standard prostanoids have the following relative efficacies as receptor ligands in binding...

The thromboxane receptor (TP) also known as the prostanoid TP receptor is a protein that in humans is encoded by the TBXA2R gene, The thromboxane receptor...

but generally with lesser affinity and responsiveness, certain other prostanoids (see Prostaglandin receptors). EP has been implicated in various physiological...

proliferation of various human cancer cell lines in culture. Prostanoids and Prostaglandin receptors Prostanoids are prostaglandins (PG), thromboxanes (TX), and prostacyclins...

the vascular network on endothelium and smooth muscle cells. Standard prostanoids have the following relative efficacies as receptor ligands in binding...

Sharif NA, Odani-Kawabata N, Lu F, Pinchuk L (April 2023). "FP and EP2 prostanoid receptor agonist drugs and aqueous humor outflow devices for treating...

little or no such amino acid sequence relationship to the eight other Prostanoid receptors (see Eicosanoid receptor#Prostenoid receptors). DP2 was found...

García Rodríguez LA (July 2001). "Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs"...

increases body temperature, resulting in fever. PGE2 is also a predominant prostanoid that contributes to inflammation via enhancing edema and leukocyte infiltration...

(prostaglandin I2) in eicosanoid nomenclature, and is a member of the prostanoids (together with the prostaglandins and thromboxane). PGI2, derived primarily...

I2 (prostacyclin) synthase (PTGIS) or CYP8A1 is an enzyme involved in prostanoid biosynthesis that in humans is encoded by the PTGIS gene. This enzyme...

and also, but with lesser affinity and responsiveness, certain other prostanoids (see Prostaglandin receptors). EP has been implicated in various physiological...

Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress". Pharmacological Reviews. 63...

family of isozymes, EC 1.14.99.1) that is responsible for biosynthesis of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from...

by inhibiting the enzyme COX, which causes the general inhibition of prostanoid biosynthesis (PGE2) within the hypothalamus. PGE2 signals to the hypothalamus...

endothelin-1, and alpha-adrenergic agonists. Various vasoactive agents, such as prostanoids, phosphodiesterase inhibitors, and endothelin antagonists, are approved...

ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo". Basic & Clinical Pharmacology...

v t e Prostanoid signaling modulators Receptor (ligands) Enzyme (inhibitors) Others Precursors: Linoleic acid γ-Linolenic acid (gamolenic acid) Dihomo-γ-linolenic...

angiogenesis, and metastasis. Thromboxane synthesis Eicosanoid synthesis Prostanoid 12-Hydroxyheptadecatrienoic acid GRCh38: Ensembl release 89: ENSG00000059377...

v t e Prostanoid signaling modulators Receptor (ligands) Enzyme (inhibitors) Others Precursors: Linoleic acid γ-Linolenic acid (gamolenic acid) Dihomo-γ-linolenic...

v t e Prostanoid signaling modulators Receptor (ligands) Enzyme (inhibitors) Others Precursors: Linoleic acid γ-Linolenic acid (gamolenic acid) Dihomo-γ-linolenic...

v t e Prostanoid signaling modulators Receptor (ligands) Enzyme (inhibitors) Others Precursors: Linoleic acid γ-Linolenic acid (gamolenic acid) Dihomo-γ-linolenic...

v t e Prostanoid signaling modulators Receptor (ligands) Enzyme (inhibitors) Others Precursors: Linoleic acid γ-Linolenic acid (gamolenic acid) Dihomo-γ-linolenic...