Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside...

A proteolysis targeting chimera (PROTAC) is a molecule that can remove specific unwanted proteins. Rather than acting as a conventional enzyme inhibitor...

thylakoid proteins encoded by a plant's nuclear genome need two targeting signals for proper localization: An N-terminal chloroplast targeting peptide (shown...

amphipathic helix. Mitochondrial targeting signals can contain additional signals that subsequently target the protein to different regions of the mitochondria...

of signal peptides and target the signal peptide for degradation, which affects virus-cellular fusion. Protein targeting Target peptide Topogenic sequence...

mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated...

In biochemical protein targeting, a peroxisomal targeting signal (PTS) is a region of the peroxisomal protein that receptors recognize and bind to. It...

Target proteins are functional biomolecules that are addressed and controlled by biologically active compounds. They are used in the processes of transduction...

target protein. The E3, which may be a multi-protein complex, is, in general, responsible for targeting ubiquitination to specific substrate proteins...

Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation...

resistant proteins. In any of these cases, proteins can potentially be targeted for degradation using the novel drug modality of proteolysis-targeting-chimeras...

Targeting may refer to: Gene targeting Protein targeting Behavioral targeting Targeted advertising Target market Geotargeting, in internet marketing Targeting...

molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a...

ten global best-selling drugs (Advair Diskus and Abilify) act by targeting G protein-coupled receptors. The exact size of the GPCR superfamily is unknown...

KKXX (amino acid sequence) KDEL (amino acid sequence) Signal peptide Protein targeting Mariano Stornaiuolo; Lavinia V. Lotti; Nica Borgese; Maria-Rosaria...

Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their...

kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure...

of protein targeting in cells. Prediction of protein subcellular localization is an important component of bioinformatics based prediction of protein function...

shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation...

Protein folding is the physical process by which a protein, after synthesis by a ribosome as a linear chain of amino acids, changes from an unstable random...

new chloroplast host had to develop a unique protein targeting system to avoid having chloroplast proteins being sent to the wrong organelle. In most,...

universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes...

Palmitic acid is anchored to the membrane bilayer and thus influence protein targeting to membrane microdomains. SCIMP is also palmitoylated and is associated...

Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...

sometimes called Critical Assessment of Protein Structure Prediction, is a community-wide, worldwide experiment for protein structure prediction taking place...

internal protein segment is removed from a precursor protein Protein structure, unique three-dimensional shape of amino acid chains Protein targeting, mechanism...

includes clogged protein targeting by the attachment of ubiquitin enzymes for degradation by the proteasome. SecY protein Sec61 Protein targeting Bacterial secretion...

unique protein targeting system to avoid having chloroplast proteins being sent to the wrong organelle. Polypeptides, the precursors of proteins, are chains...

Pea protein is a food product and protein supplement derived and extracted from yellow and green split peas, Pisum sativum. It can be used as a dietary...

of proteins targeted for degradation by the 26S proteasome. F-box domain is a protein structural motif of about 50 amino acids that mediates protein–protein...