Prothrombin complex concentrate (PCC), also known as factor IX complex, sold under the brand name Kcentra among others, is a combination medication made...
18 KB (1,479 words) - 00:15, 26 May 2025
surgery, the effects of warfarin can be reversed with vitamin K, prothrombin complex concentrate (PCC), or fresh frozen plasma (FFP). Lupus anticoagulant, a...
24 KB (3,100 words) - 14:07, 18 July 2025
with phytomenadione (vitamin K1), fresh frozen plasma, or prothrombin complex concentrate. Warfarin decreases blood clotting by blocking vitamin K epoxide...
94 KB (9,749 words) - 21:56, 30 June 2025
Thrombin (redirect from Prothrombin)
by binding to activated Factor V (Va), termed the prothrombinase complex. Prothrombin is produced in the liver and is co-translationally modified in a...
25 KB (2,932 words) - 18:47, 16 July 2025
However, if these specialized medications are not available, prothrombin complex concentrate may also be used. Only 7% of those with ICH are presented with...
44 KB (4,485 words) - 05:04, 12 July 2025
factor X deficiency. A specific FX concentrate was not available as of 2009[update]. Prothrombin complex concentrate (PCC) supplies FX with a risk of thrombosis...
6 KB (714 words) - 04:09, 15 July 2025
impaired coagulation factor synthesis or increased consumption. Prothrombin complex concentrate, cryoprecipitate and fresh frozen plasma are commonly used...
65 KB (6,736 words) - 22:51, 18 July 2025
one of the following options:[citation needed] Blood plasma Prothrombin complex concentrate, factor XIII, and fibrinogen Fibrinogen with tranexamic acid...
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VII concentrate (pdFVII) : This treatment is suitable for surgery but can lead to thrombosis. It is virus attenuated. Prothrombin complex concentrate (PCC)...
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as fresh frozen plasma (FFP), recombinant factor VIIa, and prothrombin complex concentrate (PCC) have been utilized with proven efficacy. Specifically...
81 KB (8,973 words) - 03:52, 15 July 2025
human C1-esterase inhibitor (C1-INH) concentrate Beriplex P/N, freeze-dried human prothrombin complex concentrate Haemocomplettan P, RiaSTAP, freeze-dried...
31 KB (2,916 words) - 00:11, 26 May 2025
warfarin treatment, fresh frozen plasma (FFP), vitamin K, prothrombin complex concentrates, or recombinant factor VIIa can be given to reverse the effect...
56 KB (5,877 words) - 04:35, 15 July 2025
Hypoprothrombinemia (redirect from Acquired prothrombin deficiency)
"Use of prothrombin complex concentrates for prophylaxis and treatment of bleeding episodes in patients with hereditary deficiency of prothrombin, factor...
15 KB (1,782 words) - 19:01, 1 September 2023
discontinuation of dabigatran immediately, and administration of prothrombin complex concentrate, packed red blood cells, fresh frozen plasma, the use of specific...
42 KB (3,887 words) - 04:03, 15 July 2025
Mixing study (section Correction of prothrombin time)
antibody against factor VIII, try porcine factor VIII, activated prothrombin complex concentrate FEIBA (Factor Eight Inhibitor Bypassing Agent), or NovoSeven...
16 KB (1,817 words) - 19:15, 9 June 2025
acute bleeding develops, while warfarin can be antagonised by prothrombin complex concentrate and/or vitamin K and heparin by protamine sulfate. Ximelagatran...
11 KB (980 words) - 07:46, 19 July 2025
who are actively bleeding or who require emergency surgery, prothrombin complex concentrate (ideally, four factor PCCs) should be used if available. FFP/PF24/thawed...
17 KB (1,769 words) - 00:08, 13 January 2025
tumor Posterior cingulate cortex, an anatomical brain region Prothrombin complex concentrate, a medication Propionyl-CoA carboxylase, catalyses the carboxylation...
5 KB (566 words) - 17:31, 2 August 2024
restores the prothrombin time rapidly. Severe bleeding may require blood products such as fresh frozen plasma (FFP), a prothrombin complex concentrate (PCC)...
9 KB (873 words) - 05:13, 4 May 2025
Factor Xa/Va complex which together with calcium and bound on a phospholipids surface, generate thrombin (Factor IIa) from prothrombin (Factor II). A...
27 KB (3,349 words) - 20:49, 29 May 2025
B02BD01 Coagulation factor IX, II, VII and X in combination (Prothrombin complex concentrate) B02BD02 Coagulation factor VIII B02BD03 Factor VIII inhibitor...
2 KB (311 words) - 15:18, 29 January 2025
X II/Thrombin I/Fibrinogen XIII/Catridecacog combinations: Prothrombin complex concentrate (II, VII, IX, X, protein C and S) Other systemic Batroxobin...
9 KB (973 words) - 00:54, 7 July 2025
activity. First-line treatment includes by-pass agents (activated prothrombin complex concentrates [aPCC] Factor Eight Inhibitor Bypassing Activity [FEIBA] and...
10 KB (1,468 words) - 02:37, 30 June 2025
piperazine containing linker chain. Andexanet alfa Idarucizumab Prothrombin complex concentrate Vitamin K Schubert-Zsilavecz M, Wurglics M (Fall 2015). Neue...
6 KB (317 words) - 13:25, 3 December 2023
neutralized the activity of the factor given for treatment. Prothrombin complex concentrates had been used since the 1970s as a bypassing agent in a few...
15 KB (1,914 words) - 04:19, 15 July 2025
such as in the case of major hemorrhage or surgery, 4-factor prothrombin complex concentrate (4F-PCC) is used with vitamin K to neutralize the effects of...
23 KB (2,750 words) - 22:27, 15 July 2025
73, 78 Cit. Schick KS, Fertmann JM, Kauch KW, Hoffmann JN: Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K...
9 KB (962 words) - 22:32, 17 December 2024
essentially have the same laboratory findings as DIC) Prolongation of the prothrombin time (PT) and the activated partial thromboplastin time (aPTT) reflect...
23 KB (2,460 words) - 05:37, 19 July 2025
if there are more operative ways to treat this disease. Blood tests: Prothrombin time Partial thromboplastin time "hemostasis". Merriam-Webster.com Dictionary...
18 KB (2,303 words) - 18:00, 23 December 2024
(especially platelet counts), activated partial thromboplastin time-APTT, prothrombin time with International Normalized Ratio-PTINR, thrombin time-TT, and...
48 KB (5,951 words) - 23:38, 15 June 2025