The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
22 KB (2,649 words) - 18:32, 9 June 2024
and then transport across the brush border membrane by the proton-coupled folate transporter (SLC46A1). Diffuse inflammatory or degenerative diseases of...
29 KB (3,176 words) - 17:31, 16 January 2025
"The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption"...
16 KB (1,334 words) - 15:12, 1 November 2024
absorption is primarily accomplished by the action of the proton-coupled folate transporter (PCFT) protein coded for by the SLC46A1 gene. This functions...
106 KB (11,298 words) - 16:41, 9 May 2025
Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter (PCFT)...
26 KB (2,754 words) - 15:32, 12 October 2024
Monocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1). It is a proton coupled monocarboxylate...
12 KB (1,379 words) - 02:23, 9 May 2025
regulating the concentrations of substances within them. Vesicular transporters rely on a proton gradient created by the hydrolysis of adenosine triphosphate...
9 KB (988 words) - 00:34, 19 August 2023
Solute carrier family (redirect from Sodium-dependent organic anion transporter)
(SLC10A1, SLC10A2, SLC10A3, SLC10A4, SLC10A5, SLC10A6, SLC10A7) proton coupled metal ion transporter (SLC11A1, SLC11A2) electroneutral cation-Cl cotransporter...
35 KB (3,408 words) - 02:42, 30 November 2023
cancer. HCP1 is also known as proton-coupled folate transporter (PCFT), as it was initially identified as a transporter for folate, a type of vitamin B However...
12 KB (1,428 words) - 18:07, 13 February 2024
Folate Carrier (RFC) Family 2.A.49 Chloride Carrier/Channel (ClC) Family 2.A.50 The Glycerol Uptake (GUP) Family 2.A.51 The Chromate Ion Transporter (CHR)...
38 KB (5,159 words) - 15:41, 17 April 2024
Proton-coupled amino acid transporter 2 is a protein which in humans is encoded by the SLC36A2 gene. SLC36A2 transports small amino acids (glycine, alanine...
4 KB (468 words) - 06:17, 28 January 2025
outside the cell and from vesicles. At least one zinc transporter, ZIP9, is also a G protein-coupled receptor and membrane androgen receptor. Members: ZnT1...
5 KB (421 words) - 20:53, 5 January 2024
up its concentration gradient but the coupled molecule is transported in the opposite direction. Ion transporters can be regulated in a variety of different...
17 KB (2,039 words) - 10:46, 15 November 2024
Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
11 KB (1,284 words) - 13:04, 3 May 2025
and potassium coupled glutamate transporters'. Na+-dependent transporters have also been called 'high-affinity glutamate transporters', though their...
24 KB (2,828 words) - 15:14, 24 September 2023
Sodium-coupled monocarboxylate transporter 1 (i.e., SMCT1) and sodium-coupled monocarboxylate transporter 2 (i.e., SMCT2) are plasma membrane transport...
53 KB (6,958 words) - 05:48, 26 January 2025
Antiporter (section Reduced folate carrier protein)
human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function"...
60 KB (7,840 words) - 00:16, 11 February 2025
depolarizing currents through the transporter are able to open calcium channels that are coupled to the transporter, resulting in a calcium influx in...
84 KB (9,201 words) - 10:39, 12 December 2024
Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene. This gene encodes a member of the eukaryote-specific...
6 KB (769 words) - 03:17, 1 January 2024
thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide...
25 KB (2,838 words) - 19:16, 23 November 2024
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...
31 KB (3,438 words) - 05:47, 22 August 2024
Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane, a process known as facilitated...
16 KB (1,327 words) - 21:12, 2 October 2024
Weihe E, Schütz B (February 2004). "The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated...
29 KB (3,347 words) - 04:21, 10 March 2025
The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory...
7 KB (823 words) - 10:03, 27 March 2024
Cotransporters are a subcategory of membrane transport proteins (transporters) that couple the favorable movement of one molecule with its concentration...
22 KB (2,289 words) - 23:55, 8 February 2025
Membrane transport protein (redirect from Membrane transporter)
atypical SLCs are secondary active or facilitative transporters in humans. Collectively membrane transporters and channels are known as the transportome. Transportomes...
26 KB (2,656 words) - 14:08, 8 March 2025
miscarriage, neural tube defects, and developmental delays in offspring. Folate levels may modify the presentation of symptoms and disease course. Vitamin...
110 KB (11,943 words) - 17:24, 17 May 2025
(2004). "Biophysical evidence for His57 as a proton-binding site in the mammalian intestinal transporter hPepT1". Pharm. Res. 20 (12): 1911–6. doi:10...
8 KB (935 words) - 13:52, 8 April 2024
(April 2002). "Dynamic equilibrium between coupled and uncoupled modes of a neuronal glutamate transporter". The Journal of Biological Chemistry. 277...
11 KB (1,269 words) - 04:22, 24 December 2023
The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6...
22 KB (2,503 words) - 00:44, 4 March 2023