• Thumbnail for Proton-coupled folate transporter
    The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
    22 KB (2,649 words) - 18:32, 9 June 2024
  • Thumbnail for Folate deficiency
    and then transport across the brush border membrane by the proton-coupled folate transporter (SLC46A1). Diffuse inflammatory or degenerative diseases of...
    29 KB (3,176 words) - 17:31, 16 January 2025
  • Thumbnail for Cerebral folate deficiency
    "The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption"...
    16 KB (1,334 words) - 15:12, 1 November 2024
  • Thumbnail for Folate
    absorption is primarily accomplished by the action of the proton-coupled folate transporter (PCFT) protein coded for by the SLC46A1 gene. This functions...
    106 KB (11,298 words) - 16:41, 9 May 2025
  • Thumbnail for Hereditary folate malabsorption
    Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter (PCFT)...
    26 KB (2,754 words) - 15:32, 12 October 2024
  • Thumbnail for Monocarboxylate transporter 1
    Monocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1). It is a proton coupled monocarboxylate...
    12 KB (1,379 words) - 02:23, 9 May 2025
  • regulating the concentrations of substances within them. Vesicular transporters rely on a proton gradient created by the hydrolysis of adenosine triphosphate...
    9 KB (988 words) - 00:34, 19 August 2023
  • (SLC10A1, SLC10A2, SLC10A3, SLC10A4, SLC10A5, SLC10A6, SLC10A7) proton coupled metal ion transporter (SLC11A1, SLC11A2) electroneutral cation-Cl cotransporter...
    35 KB (3,408 words) - 02:42, 30 November 2023
  • cancer. HCP1 is also known as proton-coupled folate transporter (PCFT), as it was initially identified as a transporter for folate, a type of vitamin B However...
    12 KB (1,428 words) - 18:07, 13 February 2024
  • Folate Carrier (RFC) Family 2.A.49 Chloride Carrier/Channel (ClC) Family 2.A.50 The Glycerol Uptake (GUP) Family 2.A.51 The Chromate Ion Transporter (CHR)...
    38 KB (5,159 words) - 15:41, 17 April 2024
  • Thumbnail for Proton-coupled amino acid transporter 2
    Proton-coupled amino acid transporter 2 is a protein which in humans is encoded by the SLC36A2 gene. SLC36A2 transports small amino acids (glycine, alanine...
    4 KB (468 words) - 06:17, 28 January 2025
  • outside the cell and from vesicles. At least one zinc transporter, ZIP9, is also a G protein-coupled receptor and membrane androgen receptor. Members: ZnT1...
    5 KB (421 words) - 20:53, 5 January 2024
  • Thumbnail for Ion transporter
    up its concentration gradient but the coupled molecule is transported in the opposite direction. Ion transporters can be regulated in a variety of different...
    17 KB (2,039 words) - 10:46, 15 November 2024
  • Thumbnail for Folate transporter 1
    Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
    11 KB (1,284 words) - 13:04, 3 May 2025
  • and potassium coupled glutamate transporters'. Na+-dependent transporters have also been called 'high-affinity glutamate transporters', though their...
    24 KB (2,828 words) - 15:14, 24 September 2023
  • Thumbnail for Sodium-coupled monocarboxylate transporter 1
    Sodium-coupled monocarboxylate transporter 1 (i.e., SMCT1) and sodium-coupled monocarboxylate transporter 2 (i.e., SMCT2) are plasma membrane transport...
    53 KB (6,958 words) - 05:48, 26 January 2025
  • Thumbnail for Antiporter
    human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function"...
    60 KB (7,840 words) - 00:16, 11 February 2025
  • Thumbnail for Dopamine transporter
    depolarizing currents through the transporter are able to open calcium channels that are coupled to the transporter, resulting in a calcium influx in...
    84 KB (9,201 words) - 10:39, 12 December 2024
  • Thumbnail for Proton-coupled amino acid transporter 1
    Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene. This gene encodes a member of the eukaryote-specific...
    6 KB (769 words) - 03:17, 1 January 2024
  • Thumbnail for Formylation
    thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide...
    25 KB (2,838 words) - 19:16, 23 November 2024
  • Thumbnail for Serotonin transporter
    The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...
    31 KB (3,438 words) - 05:47, 22 August 2024
  • Thumbnail for Glucose transporter
    Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane, a process known as facilitated...
    16 KB (1,327 words) - 21:12, 2 October 2024
  • Thumbnail for Vesicular monoamine transporter 2
    Weihe E, Schütz B (February 2004). "The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated...
    29 KB (3,347 words) - 04:21, 10 March 2025
  • Thumbnail for Vesicular acetylcholine transporter
    The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory...
    7 KB (823 words) - 10:03, 27 March 2024
  • Thumbnail for Cotransporter
    Cotransporters are a subcategory of membrane transport proteins (transporters) that couple the favorable movement of one molecule with its concentration...
    22 KB (2,289 words) - 23:55, 8 February 2025
  • atypical SLCs are secondary active or facilitative transporters in humans. Collectively membrane transporters and channels are known as the transportome. Transportomes...
    26 KB (2,656 words) - 14:08, 8 March 2025
  • Thumbnail for Vitamin B12
    miscarriage, neural tube defects, and developmental delays in offspring. Folate levels may modify the presentation of symptoms and disease course. Vitamin...
    110 KB (11,943 words) - 17:24, 17 May 2025
  • Thumbnail for Peptide transporter 1
    (2004). "Biophysical evidence for His57 as a proton-binding site in the mammalian intestinal transporter hPepT1". Pharm. Res. 20 (12): 1911–6. doi:10...
    8 KB (935 words) - 13:52, 8 April 2024
  • Thumbnail for Excitatory amino acid transporter 3
    (April 2002). "Dynamic equilibrium between coupled and uncoupled modes of a neuronal glutamate transporter". The Journal of Biological Chemistry. 277...
    11 KB (1,269 words) - 04:22, 24 December 2023
  • Thumbnail for Organic anion transporter 1
    The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6...
    22 KB (2,503 words) - 00:44, 4 March 2023