RNA-binding protein EWS is a protein that in humans is encoded by the EWSR1 gene on human chromosome 22, specifically 22q12.2. It is one of 3 proteins...
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RNA-binding protein fused in sarcoma/translocated in liposarcoma (FUS/TLS), also known as heterogeneous nuclear ribonucleoprotein P2 is a protein that...
32 KB (3,968 words) - 16:01, 6 February 2025
encoded by the EWSR1 gene (also termed the Ewing sarcoma RNA binding protein, EWS RNA binding protein 1, or bK984G1.4 gene) located at band 12.2 of the long...
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a gene on chromosome 22 whose mRNA is translated into the protein Ewing sarcoma breakpoint region 1 (abbreviated EWS). The gene FLI1 resides on chromosome...
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ribosomal subunits, translation initiation factors, poly(A)+ mRNA and RNA-binding proteins (RBPs). While they are membraneless organelles, stress granules...
184 KB (12,563 words) - 05:08, 10 March 2025
ERG (gene) (section EWS gene fusion)
prostate cancer, EWS-ERG in Ewing’s sarcoma, and FUS-ERG in acute myeloid leukemia. DNA binding protein ERG fuses with RNA binding proteins EWS and TLS/FUS...
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gene expression. The EWS-FLI1 fusion protein inhibits certain microRNAs of cells (such as miRNA-145). MiRNA-145 normally activates RNA-induced silencing...
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initiation factor TFIID subunit 13 is a protein that in humans is encoded by the TAF13 gene. Initiation of transcription by RNA polymerase II requires the activities...
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TAF7 (category Protein pages needing a picture)
1998). "EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68...
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11 also known as TAFII28, is a protein that in humans is encoded by the TAF11 gene. Initiation of transcription by RNA polymerase II requires the activities...
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initiation factor TFIID subunit 5 is a protein that in humans is encoded by the TAF5 gene. Initiation of transcription by RNA polymerase II requires the activities...
12 KB (1,524 words) - 04:27, 24 December 2023
BARD1 (category Proteins)
BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene. The human BARD1 protein is 777 amino acids long and contains...
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1998). "EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68...
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RBM14 (redirect from RNA-binding protein 14)
RNA-binding protein 14 is a protein that in humans is encoded by the RBM14 gene. RBM14 has been shown to interact with TARBP2. GRCh38: Ensembl release...
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PTK2B (redirect from PTK2B protein tyrosine kinase 2 beta)
"Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS". Curr. Biol. 9 (9): 485–8. Bibcode:1999CBio...
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activator of RNA proteins". Genomics. 42 (2): 268–77. doi:10.1006/geno.1997.4705. PMID 9192847. Zhang D, Childs G (1998). "Human ZFM1 protein is a transcriptional...
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Lipinski M, Harel-Bellan A (March 1996). "SRE elements are binding sites for the fusion protein EWS-FLI-1". Nucleic Acids Research. 24 (6): 1052–8. doi:10...
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DNA-directed RNA polymerases I, II, and III subunit RPABC1 is a protein that in humans is encoded by the POLR2E gene. This gene encodes the fifth largest...
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MeSH D12.776.157.725.500.500.900 – RNA-binding protein ews MeSH D12.776.157.725.500.500.905 – RNA-binding protein fus MeSH D12.776.157.725.500.625 – ribonuclease...
52 KB (4,484 words) - 16:46, 9 February 2024
ETS transcription factor family (category Protein families)
Bessho F, Yamamori S, Sugimoto T, Ohki M, Hayashi Y (1995). "EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor"....
10 KB (1,058 words) - 23:17, 24 May 2025
DNA damage-inducible transcript 3 (redirect from CCAAT/-enhancer-binding protein homologous protein)
homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3 gene. It is a member of the CCAAT/enhancer-binding protein (C/EBP)...
48 KB (5,472 words) - 11:43, 24 May 2025
Reddy ES (October 2001). "EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated...
11 KB (1,380 words) - 04:59, 25 July 2024
List of MeSH codes (D12.776) (category Protein classification)
proto-oncogene proteins b-raf MeSH D12.776.624.664.700.204.500 – proto-oncogene proteins c-raf MeSH D12.776.624.664.700.205 – RNA-binding protein EWS MeSH D12...
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Daniel A. (2003-09-01). "Identification of a DNA-binding site and transcriptional target for the EWS–WT1(+KTS) oncoprotein". Genes & Development. 17 (17):...
8 KB (1,076 words) - 02:14, 3 December 2023
KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene. This gene encodes...
22 KB (2,814 words) - 07:34, 7 April 2025
Cancer epigenetics (section MicroRNA gene silencing)
methyl-CpG binding domain proteins Methylated DNA immunoprecipitation Methyl-DIP Gene-expression profiles via DNA microarray : comparing mRNA levels from...
111 KB (12,533 words) - 12:32, 22 May 2025
TAF2N), and FUS proteins are members of the FET protein family of RNA binding proteins. They are partners in various fusion proteins that are associated...
12 KB (1,554 words) - 23:38, 25 August 2023
regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1". Cell Reports. 10 (7): 1082–95. doi:10.1016/j.celrep.2015.01.042...
57 KB (6,636 words) - 13:03, 5 January 2025
TATA-binding protein-associated factor 2N is a protein that in humans is encoded by the TAF15 gene. Initiation of transcription by RNA polymerase II requires...
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polymerase (RNA) II (DNA directed) polypeptide G". Bertolotti A, Melot T, Acker J, Vigneron M, Delattre O, Tora L (March 1998). "EWS, but not EWS-FLI-1, is...
9 KB (1,125 words) - 19:33, 9 April 2024