The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which functions in gene silencing via a variety...
36 KB (3,842 words) - 17:13, 25 November 2024
endogenously induced gene silencing effects of miRNAs as well as silencing triggered by foreign dsRNA. Mature miRNAs are structurally similar to siRNAs produced...
140 KB (15,415 words) - 03:24, 11 June 2025
miRNA and siRNA form either the RNA-induced silencing complex (RISC) or the nuclear form of RISC known as RNA-induced transcriptional silencing complex...
48 KB (5,498 words) - 13:11, 28 December 2024
Argonaute (category RNA-binding proteins)
role in RNA silencing processes as essential components of the RNA-induced silencing complex (RISC). RISC is responsible for the gene silencing phenomenon...
17 KB (2,020 words) - 19:08, 30 March 2025
RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger...
8 KB (990 words) - 15:42, 28 October 2024
the core of the RNA–protein complex termed the RNA-induced silencing complex (RISC), specifically with Argonaute protein".: 366 Small RNA have been detected...
17 KB (1,801 words) - 12:37, 3 June 2025
The siRNA-induced post transcriptional gene silencing is initiated by the assembly of the RNA-induced silencing complex (RISC). The complex silences certain...
60 KB (7,300 words) - 17:24, 6 June 2025
and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary...
147 KB (16,635 words) - 21:40, 7 May 2025
processed into 21-nucleotide-long RNA duplexes with overhangs. These segments are incorporated into an RNA-induced silencing complex (RISC) and direct the sequence-specific...
9 KB (1,153 words) - 05:22, 31 January 2024
Piwi (section piRNAs and transposon silencing)
of the RNA-induced silencing complex (RISC). In the well-known cellular process of RNA interference, the argonaute protein in the RISC complex can bind...
17 KB (1,948 words) - 02:39, 25 December 2024
Transposon silencing (or Histone Modifications) Transgene silencing Position effect RNA-directed DNA methylation RNA interference RNA silencing Nonsense...
49 KB (5,689 words) - 07:26, 2 June 2025
interference is carried out by the RNA-induced silencing complex, which uses a miRNA guide to regulate complementary mRNAs through base pairing interactions...
66 KB (7,664 words) - 19:12, 3 June 2025
Gene knockdown (section RNA interference)
exogenous siRNAs are processed by the RNA-induced silencing complex (RISC). The siRNA is complementary to the target mRNA to be silenced, and the RISC...
13 KB (1,611 words) - 03:43, 8 April 2025
Dicer (category RNA interference)
3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic component...
26 KB (3,267 words) - 20:14, 27 September 2024
of RNA splicing and RNA interference. He presented his dissertation in 2006 which was entitled Building the Drosophila RNA-induced silencing complex. After...
6 KB (507 words) - 17:00, 2 May 2025
processed by Dicer are incorporated into a complex known as the RNA-induced silencing complex or RISC. This complex contains an endonuclease that cleaves perfectly...
52 KB (6,280 words) - 16:10, 12 June 2025
piRNAs are necessary for spermatogenesis. piRNA has a role in RNA silencing via the formation of an RNA-induced silencing complex (RISC). piRNAs interact...
44 KB (5,243 words) - 05:19, 29 October 2024
into the RNA-induced silencing complex (RISC). The sense (passenger) strand is degraded. The antisense (guide) strand directs RISC to mRNA that has a...
10 KB (1,291 words) - 02:34, 25 March 2025
binding to siRNA, p19 sequesters these species and prevents them from interacting with the RNA-induced silencing complex (RISC), a protein complex that mediates...
11 KB (1,172 words) - 03:13, 29 January 2023
Viroid (redirect from Viroid RNA)
intermediate RNA, they are targeted by a dicer enzyme and cleaved into siRNAs that are then loaded onto the RNA-induced silencing complex. The viroid siRNAs contain...
51 KB (4,727 words) - 02:10, 10 May 2025
instruction set computer (RISC) principles. RNA-induced silencing complex, a multiprotein complex involved in gene silencing Rockwell Integrated Sciences Center...
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mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most...
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Sense (molecular biology) (redirect from Negative-sense RNA)
recruit RNase H to degrade the target RNA. This makes the mechanism of gene silencing catalytic. Double-stranded RNA can also act as a catalytic, enzyme-dependent...
19 KB (2,444 words) - 07:28, 20 February 2025
RDE-1 (category RNA interference)
Primary siRNA binding to RDE-1 then promotes the formation of the RNA-induced silencing complex (RISC). Unlike in other Argonautes characterized in Drosophila...
8 KB (941 words) - 11:41, 13 August 2023
Gene product (section RNA products)
negative regulation of transcription. These siRNA molecules work in RNA-induced silencing complex (RISC) during RNA interference by binding to a target DNA...
9 KB (1,186 words) - 00:53, 1 August 2024
non-coding RNA (lncRNA) transcribed from the ZMYND10 promoter. This interaction recruits the RNA-induced silencing complex (RISC), which then forms a complex with...
35 KB (3,761 words) - 19:07, 29 April 2025
Gene expression (redirect from RNA expression)
initiates the formation of the RNA-induced silencing complex (RISC), composed of the Argonaute protein. Even snRNAs and snoRNAs themselves undergo series of...
104 KB (11,629 words) - 17:28, 3 June 2025
of siRNAs. In C. elegans, siRNAs are integrated into the RNA-induced silencing complex, RISC, which works alongside mRNAs targeted for interference to...
27 KB (3,112 words) - 13:37, 27 April 2025
another eukaryotic kingdom are the sRNA directed transcriptional gene silencing (TGS) and co-transcriptional gene silencing (CTGS) pathways in Schizosaccharomyces...
139 KB (14,825 words) - 17:07, 9 June 2025
mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most...
1 KB (188 words) - 04:04, 25 March 2022