• The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which functions in gene silencing via a variety...
    36 KB (3,842 words) - 17:13, 25 November 2024
  • Thumbnail for RNA interference
    endogenously induced gene silencing effects of miRNAs as well as silencing triggered by foreign dsRNA. Mature miRNAs are structurally similar to siRNAs produced...
    140 KB (15,415 words) - 03:24, 11 June 2025
  • miRNA and siRNA form either the RNA-induced silencing complex (RISC) or the nuclear form of RISC known as RNA-induced transcriptional silencing complex...
    48 KB (5,498 words) - 13:11, 28 December 2024
  • Thumbnail for Argonaute
    Argonaute (category RNA-binding proteins)
    role in RNA silencing processes as essential components of the RNA-induced silencing complex (RISC). RISC is responsible for the gene silencing phenomenon...
    17 KB (2,020 words) - 19:08, 30 March 2025
  • RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger...
    8 KB (990 words) - 15:42, 28 October 2024
  • Thumbnail for Small RNA
    the core of the RNA–protein complex termed the RNA-induced silencing complex (RISC), specifically with Argonaute protein".: 366  Small RNA have been detected...
    17 KB (1,801 words) - 12:37, 3 June 2025
  • Thumbnail for Small interfering RNA
    The siRNA-induced post transcriptional gene silencing is initiated by the assembly of the RNA-induced silencing complex (RISC). The complex silences certain...
    60 KB (7,300 words) - 17:24, 6 June 2025
  • Thumbnail for MicroRNA
    and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary...
    147 KB (16,635 words) - 21:40, 7 May 2025
  • processed into 21-nucleotide-long RNA duplexes with overhangs. These segments are incorporated into an RNA-induced silencing complex (RISC) and direct the sequence-specific...
    9 KB (1,153 words) - 05:22, 31 January 2024
  • Thumbnail for Piwi
    of the RNA-induced silencing complex (RISC). In the well-known cellular process of RNA interference, the argonaute protein in the RISC complex can bind...
    17 KB (1,948 words) - 02:39, 25 December 2024
  • Transposon silencing (or Histone Modifications) Transgene silencing Position effect RNA-directed DNA methylation RNA interference RNA silencing Nonsense...
    49 KB (5,689 words) - 07:26, 2 June 2025
  • Thumbnail for RNA
    interference is carried out by the RNA-induced silencing complex, which uses a miRNA guide to regulate complementary mRNAs through base pairing interactions...
    66 KB (7,664 words) - 19:12, 3 June 2025
  • exogenous siRNAs are processed by the RNA-induced silencing complex (RISC). The siRNA is complementary to the target mRNA to be silenced, and the RISC...
    13 KB (1,611 words) - 03:43, 8 April 2025
  • Thumbnail for Dicer
    Dicer (category RNA interference)
    3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic component...
    26 KB (3,267 words) - 20:14, 27 September 2024
  • of RNA splicing and RNA interference. He presented his dissertation in 2006 which was entitled Building the Drosophila RNA-induced silencing complex. After...
    6 KB (507 words) - 17:00, 2 May 2025
  • Thumbnail for Messenger RNA
    processed by Dicer are incorporated into a complex known as the RNA-induced silencing complex or RISC. This complex contains an endonuclease that cleaves perfectly...
    52 KB (6,280 words) - 16:10, 12 June 2025
  • piRNAs are necessary for spermatogenesis. piRNA has a role in RNA silencing via the formation of an RNA-induced silencing complex (RISC). piRNAs interact...
    44 KB (5,243 words) - 05:19, 29 October 2024
  • Thumbnail for Short hairpin RNA
    into the RNA-induced silencing complex (RISC). The sense (passenger) strand is degraded. The antisense (guide) strand directs RISC to mRNA that has a...
    10 KB (1,291 words) - 02:34, 25 March 2025
  • Thumbnail for RNA silencing suppressor p19
    binding to siRNA, p19 sequesters these species and prevents them from interacting with the RNA-induced silencing complex (RISC), a protein complex that mediates...
    11 KB (1,172 words) - 03:13, 29 January 2023
  • Viroid (redirect from Viroid RNA)
    intermediate RNA, they are targeted by a dicer enzyme and cleaved into siRNAs that are then loaded onto the RNA-induced silencing complex. The viroid siRNAs contain...
    51 KB (4,727 words) - 02:10, 10 May 2025
  • instruction set computer (RISC) principles. RNA-induced silencing complex, a multiprotein complex involved in gene silencing Rockwell Integrated Sciences Center...
    1 KB (208 words) - 13:28, 15 November 2024
  • Thumbnail for MIR222
    mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most...
    1 KB (213 words) - 09:16, 27 March 2022
  • recruit RNase H to degrade the target RNA. This makes the mechanism of gene silencing catalytic. Double-stranded RNA can also act as a catalytic, enzyme-dependent...
    19 KB (2,444 words) - 07:28, 20 February 2025
  • RDE-1 (category RNA interference)
    Primary siRNA binding to RDE-1 then promotes the formation of the RNA-induced silencing complex (RISC). Unlike in other Argonautes characterized in Drosophila...
    8 KB (941 words) - 11:41, 13 August 2023
  • negative regulation of transcription. These siRNA molecules work in RNA-induced silencing complex (RISC) during RNA interference by binding to a target DNA...
    9 KB (1,186 words) - 00:53, 1 August 2024
  • non-coding RNA (lncRNA) transcribed from the ZMYND10 promoter. This interaction recruits the RNA-induced silencing complex (RISC), which then forms a complex with...
    35 KB (3,761 words) - 19:07, 29 April 2025
  • Thumbnail for Gene expression
    initiates the formation of the RNA-induced silencing complex (RISC), composed of the Argonaute protein. Even snRNAs and snoRNAs themselves undergo series of...
    104 KB (11,629 words) - 17:28, 3 June 2025
  • Thumbnail for RNA-dependent RNA polymerase
    of siRNAs. In C. elegans, siRNAs are integrated into the RNA-induced silencing complex, RISC, which works alongside mRNAs targeted for interference to...
    27 KB (3,112 words) - 13:37, 27 April 2025
  • Thumbnail for RNA-directed DNA methylation
    another eukaryotic kingdom are the sRNA directed transcriptional gene silencing (TGS) and co-transcriptional gene silencing (CTGS) pathways in Schizosaccharomyces...
    139 KB (14,825 words) - 17:07, 9 June 2025
  • mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most...
    1 KB (188 words) - 04:04, 25 March 2022