Repulsive guidance molecule A (RGMa) is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. Together with BMPR1A...

Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein...

Repulsive guidance molecules (RGMs) are members of a three gene family (in vertebrates) composed of RGMa, RGMb, and RGMc (also called hemojuvelin). RGMa...

Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a membrane-bound and soluble protein...

names AE12-1Y-QL and ABT-555) is a fully human monoclonal antibody developed by AbbVie against repulsive guidance molecule A (RGMa). It has been tested in...

takes place from a region called the growth cone and reaching the axon target is accomplished with relatively few guidance molecules. Growth cone receptors...

for elongation of each axon. These growth cones find signal molecules which act as guidance cues and form synapses. Connections formed between neurites...

Therapeutic, diagnostic and preventive monoclonal antibodies are clones of a single parent cell. When used as drugs, the International Nonproprietary Names...

PMC 7078468. PMID 32184239. Bell, Christian (2013). "Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub". Science. 341 (6141): 77–80. Bibcode:2013Sci...

2009). "Molecular biology, genetics and biochemistry of the repulsive guidance molecule family". The Biochemical Journal. 422 (3): 393–403. doi:10.1042/BJ20090978...

secrete repulsive semaphorin 5a and Slit in a surround fashion, covering the optic nerve which ensures that they remain in the optic nerve. Vax1, a transcription...

are caused by mutations in the hemojuvelin gene (HJV or RGMc/repulsive guidance molecule c). The exceptions, people who have mutations in the gene for...

of repulsive guidance. Robo receptors were initially identified in Drosophila melanogaster using a forward genetic screen to search for molecules involved...

filopodia are bound by a membrane which contains receptors, and cell adhesion molecules that are important for axon growth and guidance. In between filopodia—much...

improper formation of the (TEBs), suggesting that rather than acting as a guidance molecule as in neuronal systems, netrin 1 serves as an adhesive in mammary...

homologs of Down syndrome adhesion molecule. Like many neuronal receptors, Dscam proteins have multiple functions, with repulsive and attractive roles that are...

the mechanisms that determine skeletal cell fusion via RGMa (repulsive guidance molecule a) binding. GRCh38: Ensembl release 89: ENSG00000067141 – Ensembl...

within the target area by a perimeter of cues repulsive to the growth cone. Axons express patterns of cell-surface adhesion molecules that allow them to match...

109° predicted for a tetrahedral angle, and this can be explained by a repulsive interaction between the lone pairs. Various computational criteria for...

Ephrin-B2 is expressed at the chiasm midline by radial glia and acts as a repulsive signal to axons originating from the ventrotemporal retina expressing...

bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. doi:10.1016/S0092-8674(00)80590-5. PMID 10102268...

Slit refers to a secreted protein that is most widely known as a repulsive axon guidance cue, and Robo refers to its transmembrane protein receptor. There...

not your clients? And lasers, and all these supreme bacteria, all that repulsive filth, until the right moment hidden in safes? Strugatsky, Arkady and...

(Fas2 or FasII) is a 95 kilodalton cell membrane glycoprotein in the immunoglobulin (Ig) – related superfamily of cell adhesion molecules (CAMs). It was first...

PMID 8978605. S2CID 1008380. Togari A, Mogi M, Arai M, et al. (2001). "Expression of mRNA for axon guidance molecules, such as semaphorin-III, netrins and...

bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. doi:10.1016/S0092-8674(00)80590-5. PMID 10102268...

There are several other molecules also involved in the guidance of axons to and across the midline. The slit proteins have repulsive functions, as opposed...

cell-surface interaction into a repulsive response that leads to dendrite separation in da neurons is supported by Matthews et al. (2007) in a study that demonstrated...

(October 2000). "Attractive and repulsive interactions between female and male gametophytes in Arabidopsis pollen tube guidance" (PDF). Development. 127 (20):...

polarity required for axon guidance. Recent findings have shown that UNC-129 is also responsible for long range repulsive guidance of UNC-6. This mechanism...