• Thumbnail for Repulsive guidance molecule B
    Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein...
    5 KB (603 words) - 22:14, 15 July 2025
  • Thumbnail for Repulsive guidance molecule A
    Repulsive guidance molecule A (RGMa) is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. Together with BMPR1A...
    10 KB (1,138 words) - 04:41, 15 July 2025
  • Repulsive guidance molecules (RGMs) are members of a three gene family (in vertebrates) composed of RGMa, RGMb, and RGMc (also called hemojuvelin). RGMa...
    2 KB (141 words) - 10:21, 17 October 2022
  • Thumbnail for Hemojuvelin
    Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a membrane-bound and soluble protein...
    14 KB (1,834 words) - 14:58, 21 December 2023
  • target is accomplished with relatively few guidance molecules. Growth cone receptors respond to the guidance cues. Growing axons have a highly motile structure...
    33 KB (4,365 words) - 08:32, 24 May 2025
  • fully human monoclonal antibody developed by AbbVie against repulsive guidance molecule A (RGMa). It has been tested in people with multiple sclerosis...
    5 KB (315 words) - 22:42, 25 June 2025
  • for elongation of each axon. These growth cones find signal molecules which act as guidance cues and form synapses. Connections formed between neurites...
    55 KB (6,888 words) - 06:05, 9 June 2025
  • Thumbnail for Growth cone
    membrane which contains receptors, and cell adhesion molecules that are important for axon growth and guidance. In between filopodia—much like the webbing of...
    15 KB (1,695 words) - 15:26, 29 September 2024
  • Thumbnail for Netrin
    formation of the (TEBs), suggesting that rather than acting as a guidance molecule as in neuronal systems, netrin 1 serves as an adhesive in mammary...
    33 KB (4,169 words) - 20:50, 23 September 2024
  • Thumbnail for Retinal ganglion cell
    Neural cell adhesion molecule (N-CAM) will mediate this attachment via homophilic interactions between molecules of like isoforms (A or B). Slit signaling...
    30 KB (3,681 words) - 05:13, 12 May 2025
  • Thumbnail for DSCAM
    homologs of Down syndrome adhesion molecule. Like many neuronal receptors, Dscam proteins have multiple functions, with repulsive and attractive roles that are...
    32 KB (3,767 words) - 16:24, 17 July 2025
  • Thumbnail for Tropic cues involved in growth cone guidance
    of repulsive guidance. Robo receptors were initially identified in Drosophila melanogaster using a forward genetic screen to search for molecules involved...
    26 KB (3,143 words) - 23:07, 24 May 2025
  • target area by a perimeter of cues repulsive to the growth cone. Axons express patterns of cell-surface adhesion molecules that allow them to match with specific...
    9 KB (1,223 words) - 18:52, 5 January 2025
  • Thumbnail for Lone pair
    109° predicted for a tetrahedral angle, and this can be explained by a repulsive interaction between the lone pairs. Various computational criteria for...
    23 KB (2,957 words) - 08:07, 16 March 2025
  • not your clients? And lasers, and all these supreme bacteria, all that repulsive filth, until the right moment hidden in safes? Strugatsky, Arkady and...
    61 KB (7,449 words) - 10:02, 28 July 2025
  • Thumbnail for Iron metabolism disorder
    are caused by mutations in the hemojuvelin gene (HJV or RGMc/repulsive guidance molecule c). The exceptions, people who have mutations in the gene for...
    4 KB (365 words) - 23:26, 27 May 2025
  • Thumbnail for Organic acid anhydride
    PMC 7078468. PMID 32184239. Bell, Christian (2013). "Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub". Science. 341 (6141): 77–80. Bibcode:2013Sci...
    18 KB (2,083 words) - 15:43, 24 May 2025
  • Thumbnail for ROBO1
    bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. doi:10.1016/S0092-8674(00)80590-5. PMID 10102268...
    10 KB (1,234 words) - 18:12, 17 July 2025
  • Thumbnail for Netrin 1
    Togari A, Mogi M, Arai M, et al. (2001). "Expression of mRNA for axon guidance molecules, such as semaphorin-III, netrins and neurotrophins, in human osteoblasts...
    10 KB (1,335 words) - 17:35, 17 July 2025
  • Thumbnail for Neural crest
    progenitor cells, neural crest migration is the result of repulsive guidance via EphB/EphrinB and semaphorin/neuropilin signaling, interactions with the...
    41 KB (4,610 words) - 04:30, 15 July 2025
  • Thumbnail for Pollen tube
    (October 2000). "Attractive and repulsive interactions between female and male gametophytes in Arabidopsis pollen tube guidance" (PDF). Development. 127 (20):...
    49 KB (6,541 words) - 09:21, 11 July 2025
  • Thumbnail for NEO1
    the mechanisms that determine skeletal cell fusion via RGMa (repulsive guidance molecule a) binding. GRCh38: Ensembl release 89: ENSG00000067141 – Ensembl...
    6 KB (689 words) - 22:03, 15 July 2025
  • functions including axon guidance and angiogenesis. Slit refers to a secreted protein that is most widely known as a repulsive axon guidance cue, and Robo refers...
    34 KB (4,080 words) - 00:05, 27 May 2025
  • Thumbnail for Netrin receptor DCC
    There are several other molecules also involved in the guidance of axons to and across the midline. The slit proteins have repulsive functions, as opposed...
    39 KB (5,119 words) - 07:20, 9 June 2025
  • Thumbnail for Neuronal self-avoidance
    neuronal self-recognition is attained through families of cell recognition molecules which work as individual barcodes, allowing the discrimination of any...
    41 KB (5,789 words) - 02:43, 4 July 2025
  • Thumbnail for Bomb
    while being exposed to a neutron source. If consolidation occurs slowly, repulsive forces drive the material apart before a significant explosion can occur...
    31 KB (3,710 words) - 16:40, 4 May 2025
  • Thumbnail for Selective estrogen receptor modulator
    create a strong repulsive force towards the other subtype receptor. In addition, the structure of the ligand must be rigid. Repulsive interactions may...
    58 KB (6,624 words) - 05:22, 30 July 2025
  • Nambudripad characterizes an allergy as a condition caused by these "repulsive electromagnetic fields between an individual and the object (allergen)"...
    19 KB (1,981 words) - 20:33, 23 July 2025
  • migration is enhanced by geometrical confinement of an extracellular matrix molecule (e.g. the proteoglycan versican in neural crest cells), that acts as a...
    20 KB (2,242 words) - 08:30, 9 June 2025
  • and used in his book Gulliver's Travels. It represents a person who is repulsive in appearance and action and is barely human. Yahoo! founders Jerry Yang...
    51 KB (6,422 words) - 09:45, 29 July 2025