• Thumbnail for Silent mutation
    Silent mutations, also called synonymous or samesense mutations, are mutations in DNA that do not have an observable effect on the organism's phenotype...
    27 KB (3,318 words) - 23:55, 19 June 2025
  • three types of point mutations; silent mutations, missense mutations and nonsense mutations. Silent mutations A silent mutation occurs when a change in...
    84 KB (10,140 words) - 11:27, 9 June 2025
  • Thumbnail for Point mutation
    non-conservative (missense) mutation. Silent mutations code for the same amino acid (a "synonymous substitution"). A silent mutation does not affect the functioning...
    40 KB (4,856 words) - 04:49, 18 June 2025
  • Thumbnail for Point accepted mutation
    include all point mutations in the DNA of an organism. In particular, silent mutations are not point accepted mutations, nor are mutations that are lethal...
    33 KB (4,444 words) - 18:59, 7 June 2025
  • phenotype. There are various forms of mutations that can occur in coding regions. One form is silent mutations, in which a change in nucleotides does...
    22 KB (2,514 words) - 21:25, 25 May 2025
  • Thumbnail for Mutation
    In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain...
    119 KB (14,264 words) - 07:00, 9 June 2025
  • Thumbnail for Missense mutation
    substitution, or a silent mutation, and not a missense mutation. Missense mutations may be inherited or arise spontaneously, termed de novo mutations. Well studied...
    45 KB (4,553 words) - 15:58, 22 May 2025
  • synonymous if a point mutation at that site would not change the amino acid, also known as a silent mutation. Because the mutation did not result in a change...
    18 KB (2,300 words) - 17:04, 10 February 2024
  • Thumbnail for Synonymous substitution
    substitutions and mutations affecting noncoding DNA are often considered silent mutations; however, it is not always the case that the mutation is silent. Since...
    9 KB (1,121 words) - 15:46, 8 November 2023
  • genetics, mutations in which natural selection does not affect the spread of the mutation in a species are termed neutral mutations. Neutral mutations that...
    25 KB (3,429 words) - 19:38, 9 April 2025
  • Thumbnail for Genetics
    Genetics (section Mutations)
    Mendel published. In his third law, he developed the basic principles of mutation (he can be considered a forerunner of Hugo de Vries). Festetics argued...
    100 KB (10,512 words) - 11:36, 23 June 2025
  • very seldom advantageous. In most instances, they indicate a (non-silent) mutation, which is almost certain to be deleterious. It therefore behooves sexual...
    77 KB (8,218 words) - 22:03, 22 May 2025
  • Thumbnail for Single-nucleotide polymorphism
    affect its function in other ways. An example would be a seemingly silent mutation in the multidrug resistance gene 1 (MDR1), which codes for a cellular...
    58 KB (6,253 words) - 23:44, 28 April 2025
  • Thumbnail for Genetic code
    that errors in the third position of the triplet codon cause only a silent mutation or an error that would not affect the protein because the hydrophilicity...
    74 KB (8,077 words) - 08:20, 5 June 2025
  • substitutions, which do not alter amino acid sequences and are (sometimes) silent mutations. As nonsynonymous substitutions result in a biological change in the...
    8 KB (979 words) - 18:55, 4 August 2022
  • Thumbnail for Mutation rate
    single type of mutation; there are many different types of mutations. Mutation rates are given for specific classes of mutations. Point mutations are a class...
    28 KB (3,328 words) - 09:52, 8 June 2025
  • Though the term "silent mutation" is often used interchangeably with synonymous mutation, synonymous mutations are not always silent, nor vice versa....
    300 KB (26,633 words) - 14:01, 23 June 2025
  • Sigma factor Signal hypothesis Signal peptide Signal peptide Silent gene Silent mutation SINE Single-gene disorder Sister chromatids Skew Smooth endoplasmic...
    33 KB (2,517 words) - 18:31, 3 September 2024
  • speciation). The genetic differences among divergent populations can involve silent mutations (that have no effect on the phenotype) or give rise to significant...
    7 KB (809 words) - 00:46, 24 May 2025
  • Thumbnail for Golden Gate Cloning
    sure that the introduced mutation will not affect the genetic function encoded by the sequence of interest. A silent mutation in the coding sequence is...
    18 KB (2,496 words) - 18:18, 31 October 2024
  • = m/+ = m/Dp After Muller's classification of gene mutation, an isomorph was described as a silent point mutant with identical gene expression as the...
    7 KB (669 words) - 18:22, 28 September 2024
  • Thumbnail for Mutagen
    Mutagen (category Mutation)
    organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer in animals, such mutagens...
    51 KB (6,003 words) - 15:54, 19 May 2025
  • Thumbnail for Phenotype
    level of the gene which affect an organism's fitness. For example, silent mutations that do not change the corresponding amino acid sequence of a gene...
    31 KB (3,310 words) - 02:17, 7 June 2025
  • Thumbnail for Gene polymorphism
    to be clear when discussing mutations whether it is a somatic mutation or germline mutation. In the case of silent mutations there isn't a change in fitness...
    21 KB (2,529 words) - 20:56, 29 May 2025
  • Thumbnail for Sequence alignment
    difference in acceptance rates between silent mutations that do not alter the meaning of a given codon and other mutations that result in a different amino...
    56 KB (6,913 words) - 09:31, 31 May 2025
  • is used to estimate the balance between neutral mutations, purifying selection and beneficial mutations acting on a set of homologous protein-coding genes...
    22 KB (2,755 words) - 19:59, 1 February 2024
  • Gene duplication (category Mutation)
    selective pressure—that is, mutations of it have no deleterious effects to its host organism. If one copy of a gene experiences a mutation that affects its original...
    34 KB (3,683 words) - 00:52, 1 June 2025
  • and physical properties of the nucleotides in the DNA and some mutations being "silent" (that is, not altering gene expression), the DNA primary sequence...
    12 KB (1,397 words) - 02:43, 28 May 2025
  • Thumbnail for Nucleic acid sequence
    difference in acceptance rates between silent mutations that do not alter the meaning of a given codon and other mutations that result in a different amino...
    22 KB (2,409 words) - 19:05, 21 May 2025
  • The molecular clock is a figurative term for a technique that uses the mutation rate of biomolecules to deduce the time in prehistory when two or more...
    32 KB (3,699 words) - 12:04, 16 June 2025