In chemistry, solid-phase synthesis is a method in which molecules are covalently bound on a solid support material and synthesised step-by-step in a single...

in most research and development settings by solid-phase methods (see below). Solution-phase synthesis retains its usefulness in large-scale production...

opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks...

advantageous in solid-phase peptide synthesis (SPPS), where its compatibility with other reagents and ease of removal streamline synthesis workflows. Upon...

Noncovalent solid-phase organic synthesis (NC-SPOS) is a form of solid-phase synthesis whereby the organic substrate is bonded to the solid phase not by a...

molecule on a solid support prior to performing polymerisation. This is analogous to solid-phase synthesis of peptides. The solid phase doubles as an...

1021/cr00038a004. Nielsen, T. E.; Diness, F.; Meldal, M. (2003). "Solid-Phase Synthesis of Pyrroloisoquinolines via the Intramolecular N-Acyliminium Pictet-Spengler...

Fmoc solid-phase synthesis of peptides. The chemical synthesis of large peptides is still limited by problems of low solvation during solid phase peptide...

synthesized using the Dakin–West reaction. Recently, a solid-phase version of the Robinson–Gabriel synthesis has been described. The reaction requires trifluoroacetic...

method for solid-phase synthesis of β-mannosides, which has great potential to be further extended, was established. Carbohydrate synthesis Difficult linkages[broken...

Solid-state chemistry, also sometimes referred as materials chemistry, is the study of the synthesis, structure, and properties of solid phase materials...

University, Bruce Merrifield, started investigating the solid-phase synthesis of peptides. Synthesis of peptides in a combinatorial fashion quickly leads...

made polyamides can be made through step-growth polymerization or solid-phase synthesis yielding materials such as nylons, aramids, and sodium polyaspartate...

Merrifield (1984 winner of the Nobel Prize in Chemistry) and is used in solid-phase synthesis. The material is typically available as white beads. These beads...

spherical polymer beads used in synthetic chemistry, specifically solid-phase synthesis Synthetic resin, an artificial chemical substance which hardens...

1021/jo970846u. Wipf, P.; Cunningham, A. (1995). "A solid phase protocol of the biginelli dihydropyrimidine synthesis suitable for combinatorial chemistry". Tetrahedron...

biological methods. One of the chemical polymerization methods is solid-phase synthesis, which can be used to synthesize peptides consisted of natural and...

CuFe2O4 can be synthesized by solid phase synthesis at high temperature. In a particular procedure for this type of synthesis, the stoichiometric mixture...

won the Nobel Prize in Chemistry in 1984 for the invention of solid phase peptide synthesis. He was born in Fort Worth, Texas, on 15 July 1921, the only...

usually the result of enzymatic modification after translation (protein synthesis). For example, phosphorylation of serine by kinases and dephosphorylation...

preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis". Journal of the American Chemical Society. 114 (26): 10646–10647...

Daniel M.; Wilson, L.J.; Portlock, D.E. (2000). "The solid-phase Nenitzescu indole synthesis". Tetrahedron Letters. 41 (33): 6253–6257. doi:10...

surface of solid catalyst; transfer of aqueous phase inside the pore volume of solid catalyst; transfer of the substrate from aqueous phase to the interphase...

It is widely used for amide and ester formation, especially for solid-phase synthesis of peptides. DCC has achieved popularity mainly because of its high-yielding...

In 1828, Friedrich Wöhler published a paper on his serendipitous urea synthesis from potassium cyanate and ammonium sulfate; some regarded that as a direct...

catalytic properties. Some enzymes are used commercially, for example, in the synthesis of antibiotics. Some household products use enzymes to speed up chemical...

Optimer selection. Optimer ligands are produced via solid-phase synthesis. Solid-phase chemical synthesis was invented in the 1960s by Robert Bruce Merrifield...

Virtue of the Multifunctional Triazene Linkers in the Efficient Solid-Phase Synthesis of Heterocycle Libraries". Accounts of Chemical Research. 37 (10):...

Organic synthesis Peptide synthesis Radiosynthesis Retrosynthesis Semisynthesis Solid-phase synthesis Solvothermal synthesis Total synthesis Volume combustion...

ribonucleoside 3'-O-phosphoramidites and their application to the automated solid phase synthesis of oligonucleotides". Tetrahedron Lett. 26 (38): 4567–4570. doi:10...