Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck...

Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...

C-terminal end of Src-family kinases (SFKs) including SRC, HCK, FYN, LCK, LYN and YES1. This Non-receptor tyrosine-protein kinase plays an important...

Tyrosine-protein kinase Lyn is a protein that in humans is encoded by the LYN gene. Lyn is a member of the Src family of protein tyrosine kinases, which is mainly...

sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family. This gene lies in close proximity to thymidylate synthase...

constitutive activation of downstream signaling molecules such as Src-family kinases.[citation needed] CML has a well defined molecular target and relatively...

Moarefi I, Kuriyan J (February 1997). "Crystal structure of the Src family tyrosine kinase Hck". Nature. 385 (6617): 602–609. Bibcode:1997Natur.385..602S...

2009). "CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells". Immunological Reviews. 228 (1):...

a type of kinase in the Src family that was identified in the nuclear matrix, appears to control the cell cycle. Src family tyrosine kinases are closely...

and encoded in the human by the LCK gene. The Lck is a member of Src kinase family (SFK) and is important for the activation of T-cell receptor (TCR)...

domain. However, activation of SYK relies less on phosphorylation by Src family kinases than ZAP70. SYK and ZAP70 share a common evolutionary origin and split...

kinase BLK, also known as B lymphocyte kinase, is a non-receptor tyrosine kinase that in humans is encoded by the BLK gene. It is of the Src family of...

locomotive built in 1897 for the Lynton and Barnstaple Railway Lyn (Src family kinase), in biochemistry LyN, a video game engine Lyn Me, a character in...

In some cases PTPs positively regulate nRTKs activity. Tyrosine kinases of Src family contain the same typical structure: myristoylated terminus, a region...

tyrosine-phosphorylated receptors (NTRs), also called immunoreceptors or Src-family kinase-dependent receptors, are a group of cell surface receptors expressed...

in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows...

amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain...

tyrosine-protein kinase Fyn (p59-FYN, Slk, Syn, MGC45350, Gene ID 2534) is an enzyme that in humans is encoded by the FYN gene. Fyn is a 59-kDa member of the Src family...

intracellular domain is a tyrosine kinase that phosphorylates its partner in the receptor. The Src-family kinases are examples of proteins that utilize...

SK, Henriksen KJ, Long CG, Vives F, Bluestone JA (May 2002). "The Src family kinase Fyn mediates signals induced by TCR antagonists". Journal of Immunology...

AstraZeneca. It acts as a dual kinase inhibitor, with selective actions as a Src inhibitor and a Bcr-Abl tyrosine-kinase inhibitor. It was originally under...

(D/E)xxYxx(L/I)x6-8Yxx(L/I)). Src family kinases phosphorylate tyrosine in ITAM sequence. It results in recruitment of tyrosine kinases Syk and ZAP-70 by the...

DT (April 1994). "Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene". Gene. 138 (1–2): 247–51. doi:10.1016/0378-1119(94)90817-6...

PRL-R). The distinguishing feature between janus kinase 2 and other JAK kinases is the lack of Src homology binding domains (SH2/SH3) and the presence...

coppice, an energy crop Src (gene), a family of proto-oncogenic tyrosine kinases SRC, the human orthologue of the Src gene SRC Computers, a company founded...

non-receptor tyrosine kinase originally identified as a substrate for the oncogene protein tyrosine kinase v-src. This cytosolic kinase has been implicated...

SU6656 is a Src family kinase inhibitor developed by the biotechnology company SUGEN Inc (a subsidiary of Pharmacia) in 2000. SU6656 was initially identified...

PMID 15122207. S2CID 6939454. Summy JM, Gallick GE (December 2003). "Src family kinases in tumor progression and metastasis". Cancer and Metastasis Reviews...

K, Emmerich B, Hallek M (December 1997). "The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding...

(14 January 2020). "WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility". bioRxiv: 2020.01.14.906784...