• Thumbnail for Substituted tryptamine
    Substituted tryptamines, or simply tryptamines, also known as serotonin analogues (i.e., 5-hydroxytryptamine analogues), are organic compounds which may...
    83 KB (2,418 words) - 05:29, 17 June 2025
  • Thumbnail for Substituted phenethylamine
    derivatives such as Substituted amphetamines, where there is a methyl group substituted at the alpha position on the ethyl chain, Substituted methylenedioxyphenethylamines...
    32 KB (970 words) - 20:24, 9 June 2025
  • Thumbnail for Tryptamine
    Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole...
    55 KB (4,284 words) - 23:56, 17 June 2025
  • methylenedioxyphenethylamine Substituted phenethylamine Substituted phenylmorpholine Substituted tryptamine Laras, Y.; Garino, C.; Dessolin, J.; Weck, C.; Moret...
    18 KB (994 words) - 19:08, 6 June 2025
  • Thumbnail for Substituted methoxyphenethylamine
    doses. This is in notable contrast to substituted tryptamines such as DET, which require no specific ring substitutions to be psychedelic. Monomethoxyphenethylamines...
    19 KB (1,811 words) - 01:46, 1 June 2025
  • Thumbnail for Lysergamides
    Hofmann and colleagues by 1955. Ergoline Partial lysergamide Substituted tryptamine Substituted phenethylamine Jamieson CS, Misa J, Tang Y, Billingsley JM...
    58 KB (3,277 words) - 01:20, 14 June 2025
  • Thumbnail for Substituted β-hydroxyamphetamine
    List of aminorex analogues List of methylphenidate analogues Substituted tryptamine Substituted α-alkyltryptamines PiHKAL Glennon RA (2014). "Bath salts,...
    26 KB (1,516 words) - 23:59, 9 May 2025
  • Thumbnail for 4-HO-DET
    4-HO-DET (category Psychedelic tryptamines)
    as ethocin or CZ-74, is a psychedelic drug of the tryptamine family. It is a substituted tryptamine, structurally related to psilocin, ethocybin, and...
    9 KB (648 words) - 09:36, 24 May 2025
  • Thumbnail for 5,6-Dibromo-DMT
    5,6-Dibromo-DMT (category Tryptamine alkaloids)
    6-Br-DMT) is a substituted tryptamine alkaloid found in some marine sponges. It is briefly mentioned in Alexander Shulgin's book TiHKAL (Tryptamines I Have Known...
    3 KB (155 words) - 08:25, 27 March 2025
  • Thumbnail for 4-Hydroxytryptamine
    in 2024. Substituted tryptamine 6-Hydroxytryptamine Keeper of the Trout and Friends (2007). "4-Hydroxytryptamine". Some Simple Tryptamines (2 ed.). Austin...
    16 KB (1,403 words) - 00:15, 18 June 2025
  • Thumbnail for Pyr-T
    behavioral proxy of psychedelic effects, in rodents. Pyr-T is a substituted tryptamine in which the amine moiety has been replaced with a pyrrolidine ring...
    10 KB (896 words) - 06:51, 11 June 2025
  • Thumbnail for Substituted amphetamine
    phenylmorpholines Substituted methoxyphenethylamine 2Cs, DOx, 4Cs, 25-NB, 3C, substituted mescaline analogue, FLY Substituted tryptamines Substituted α-alkyltryptamines...
    36 KB (1,768 words) - 04:50, 11 May 2025
  • Bufotoxins are a family of toxic steroid lactones or substituted tryptamines of which some are toxic. They occur in the parotoid glands, skin, and poison...
    10 KB (903 words) - 20:01, 3 June 2025
  • Thumbnail for Isotryptamine
    compound and positional isomer of tryptamine (2-(3-indolyl)ethylamine). A variety of isotryptamine derivatives, or substituted isotryptamines, have been developed...
    10 KB (952 words) - 03:31, 5 May 2025
  • Thumbnail for Α,N-DMT
    analogue of αMT. There are notable parallels between the substituted tryptamines and substituted phenethylamines here in that α,N-DMT is to αMT as methamphetamine...
    5 KB (368 words) - 08:42, 10 April 2025
  • Thumbnail for 4-HO-MET
    4-HO-MET (category Psychedelic tryptamines)
    PMID 30467466. 4-OH-MET (4-Hydroxy-N-methyl-N-ethyltryptamine): substituted tryptamine and close analog of psilocin, first synthesized by A. Shulgin (Shulgin...
    20 KB (1,288 words) - 02:34, 31 May 2025
  • Thumbnail for 5-Methoxytryptamine
    5-methoxytryptamine or as 5-hydroxytrypamine O-methyl ether, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine) and precursor...
    30 KB (2,667 words) - 00:21, 18 June 2025
  • Thumbnail for Serotonin
    serotonergic psychedelics, like psilocin, DMT, and 5-MeO-DMT, are substituted tryptamines and are very similar in chemical structure to serotonin. Serotonin...
    173 KB (18,295 words) - 19:45, 2 June 2025
  • Thumbnail for Α-Methyltryptamine
    Α-Methyltryptamine (category Psychedelic tryptamines)
    oxidase inhibitor. αMT is a substituted tryptamine and is closely related to α-ethyltryptamine (αET) and other α-alkylated tryptamines. αMT appears to have first...
    48 KB (4,239 words) - 04:48, 15 June 2025
  • Thumbnail for Acetryptine
    marketed. Structurally, acetryptine is a substituted tryptamine, and is closely related to other substituted tryptamines like serotonin (5-hydroxytryptamine)...
    4 KB (299 words) - 19:14, 16 April 2025
  • Thumbnail for Substituted benzofuran
    Substituted methoxyphenethylamine Substituted naphthylethylamine Substituted phenethylamine Substituted tryptamines Dawood KM (September 2013). "Benzofuran...
    18 KB (1,121 words) - 10:05, 10 April 2025
  • Thumbnail for 5-HO-DET
    scientific literature by Hunt and Brimblecombe by at least 1967. Substituted tryptamine 5-HO-DPT 5-HO-DiPT α-Methylserotonin (5-HO-AMT) N-Methylserotonin...
    5 KB (401 words) - 02:54, 18 June 2025
  • TiHKAL (category Psychedelic tryptamines)
    Psychedelic Phenethylamines and Related Compounds (2011) Substituted tryptamine Substituted lysergamide Ben Sessa (2015). "Continuing History of Psychedelics...
    8 KB (460 words) - 00:41, 21 May 2025
  • Thumbnail for BK-NM-AMT
    dopamine release. In contrast to many other tryptamines however, these novel β-keto-substituted tryptamine derivatives are inactive as agonists of serotonin...
    11 KB (698 words) - 06:49, 8 May 2025
  • Thumbnail for Substituted methylenedioxyphenethylamine
    Substituted cathinones Substituted phenethylamines Substituted phenmetrazines Substituted tryptamines PiHKAL The Shulgin Index Trachsel D, Lehmann D, Enzensperger...
    26 KB (569 words) - 01:00, 21 May 2025
  • Thumbnail for Milipertine
    of schizophrenia but was never marketed. Structurally, it is a substituted tryptamine and a piperazinylethylindole. The drug is closely structurally related...
    9 KB (675 words) - 17:23, 27 March 2025
  • Thumbnail for 4-HO-EiBT
    4-Hydroxy-N-ethyl-N-isobutyltryptamine (4-HO-EiBT, Eibucin) is a substituted tryptamine derivative which acts as a 5-HT2A receptor agonist, with an EC50...
    1 KB (83 words) - 02:21, 13 May 2025
  • Thumbnail for Β-Carboline
    structure of the substituted β-carbolines, a large group of alkaloids and synthetic compounds. β-Carboline may be thought of as a cyclized tryptamine. The compound...
    3 KB (126 words) - 00:56, 26 May 2025
  • Thumbnail for Substituted β-carboline
    A substituted β-carboline is a chemical compound featuring a β-carboline moiety with one or more substitutions. β-Carbolines include more than one hundred...
    49 KB (4,767 words) - 03:34, 18 June 2025
  • Thumbnail for 4-HO-MPT
    4-HO-MPT (category Psychedelic tryptamines)
    psychedelic drug in the tryptamine class of chemical compounds and is a higher homologue of the naturally occurring substituted tryptamine psilocin as well as...
    5 KB (324 words) - 00:12, 11 April 2025