Syndecan-2 is a protein that in humans is encoded by the SDC2 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan...
10 KB (1,283 words) - 08:04, 16 May 2025
Syndecans are single transmembrane domain proteins that are thought to act as coreceptors, especially for G protein-coupled receptors. More specifically...
20 KB (2,370 words) - 19:38, 26 May 2025
Syndecan-4 is a protein that in humans is encoded by the SDC4 gene. Syndecan-4 is one of the four vertebrate syndecans and has a molecular weight of ~20...
16 KB (2,088 words) - 18:50, 22 December 2023
Syndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein is a transmembrane (type I) heparan sulfate proteoglycan and is a member...
22 KB (2,522 words) - 10:04, 27 March 2024
alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4". J. Biol. Chem. 276 (31): 28779–88. doi:10.1074/jbc.M101420200...
10 KB (1,238 words) - 04:40, 25 December 2023
most prominent was syndecan-1 (SDC1). In confirmatory pull-down assays, binding was not shared with family members syndecan-2 or syndecan-4, indicating that...
44 KB (5,202 words) - 05:07, 9 May 2025
STAT1, and STAT3. CD361 Also known as EVI2B. CD362 Also known as SDC2, Syndecan-2. CD363 S1PR1 (Sphingosine-1-phosphate receptor 1) or EDG1. It is a G-protein-coupled...
96 KB (492 words) - 06:06, 25 November 2024
protein, is found to interact with multiple molecules including neurexin, syndecan and Mint1, playing an important synaptic function, and also possibly plays...
19 KB (2,058 words) - 19:17, 24 May 2025
CASK (category EC 2.7.11)
TBR1 and binds to several cell-surface proteins including neurexins and syndecans. This gene has been implicated in X-linked mental retardation, including...
26 KB (2,910 words) - 02:21, 1 January 2025
PMID 11042152. Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1):...
4 KB (404 words) - 00:53, 4 March 2023
Hyaluronidase (redirect from EC 3.2.1.34)
Srivastava LM, Bhargava S (July 2016). "Evolution of serum hyaluronan and syndecan levels in prognosis of sepsis patients". Clinical Biochemistry. 49 (10–11):...
35 KB (3,172 words) - 09:46, 22 May 2025
Syndecan-3 is a protein that in humans is encoded by the SDC3 gene. GRCh38: Ensembl release 89: ENSG00000162512 – Ensembl, May 2017 GRCm38: Ensembl release...
7 KB (874 words) - 23:17, 23 December 2023
1074/jbc.M010647200. PMID 11152476. "Entrez Gene: SDCBP2 syndecan binding protein (syntenin) 2". Andersson B, Wentland MA, Ricafrente JY, et al. (1996)...
4 KB (456 words) - 07:23, 19 August 2023
apoptosis of specific cells, including tumour cells. Other OPG ligands include syndecan-1, glycosaminoglycans, von Willebrand factor, and factor VIII-von Willebrand...
30 KB (3,687 words) - 20:28, 17 May 2024
Mucin 2, oligomeric mucus gel-forming, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the...
2 KB (316 words) - 00:35, 4 March 2023
S2CID 24896178. Asundi VK, Carey DJ (1995). "Self-association of N-syndecan (syndecan-3) core protein is mediated by a novel structural motif in the transmembrane...
14 KB (1,649 words) - 07:53, 21 December 2023
Fibronectin (category Genes on human chromosome 2)
proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans). Fibronectin exists as a protein dimer, consisting of two nearly identical...
33 KB (3,682 words) - 21:43, 24 May 2025
the immunoglobulin superfamily cell adhesion molecules, selectins and syndecans, to mediate cell–cell and cell–matrix interaction. Ligands for integrins...
36 KB (3,928 words) - 22:54, 6 February 2025
ALOX15 (redirect from Arachidonate 15-lipoxygenase-2)
"15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cells". Carcinogenesis. 34...
44 KB (5,708 words) - 18:03, 29 November 2024
B-cells are CD27+ and plasma cells are CD27++. The surface antigen CD138 (syndecan-1) is expressed at high levels. Another important surface antigen is CD319...
24 KB (2,793 words) - 18:53, 24 May 2025
incomplete and ongoing. Known-related groups include: The gel-forming mucins (2, 5AC, 5B, 6, 19) are related both to each other and to otogelin and von Willebrand...
22 KB (2,344 words) - 00:32, 24 May 2025
RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1617 (1–2): 80–88. doi:10...
67 KB (7,900 words) - 15:35, 19 February 2025
Apolipoprotein H (redirect from Beta-2 glycoprotein I)
β2-glycoprotein 1, also known as beta-2 glycoprotein 1 and Apolipoprotein H (Apo-H), is a 38 kDa multifunctional plasma protein that in humans is encoded...
12 KB (1,419 words) - 19:08, 13 August 2023
metastatic breast cancer and metastatic urinary bladder cancer. CD138 (Syndecan-1) is highly overexpressed on various solid tumors and in hematological...
3 KB (198 words) - 19:21, 6 May 2024
role in SARS-CoV-2 infection, particularly when the virus attaches with ACE2. The major cell membrane HSPGs are the transmembrane syndecans and the...
36 KB (4,162 words) - 19:16, 23 May 2025
protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly...
11 KB (1,267 words) - 07:46, 15 January 2024
CSPG4 (redirect from Neuron-glial antigen 2)
melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by...
12 KB (1,501 words) - 22:27, 26 May 2025
cross-reactive monoclonal antibodies". Journal of Ovarian Research. 2 (1): 8. doi:10.1186/1757-2215-2-8. PMC 2708168. PMID 19538730. Palmai-Pallag T, Khodabukus...
16 KB (1,916 words) - 18:26, 3 December 2023
and Hp2-2. Hp of different genotypes have been shown to bind hemoglobin with different affinities, with Hp2-2 being the weakest binder. Allele 2 encodes...
26 KB (2,899 words) - 06:30, 25 May 2025