Tissue inhibitor of metalloproteinases 2 (TIMP2) is a gene and a corresponding protein. The gene is a member of the TIMP gene family. The protein is thought...
8 KB (918 words) - 07:33, 19 July 2025
properties of HSCs, leading to fibrosis. Furthermore, HSCs secrete TIMP1 and TIMP2, naturally occurring inhibitors of matrix metalloproteinases (MMPs), which...
120 KB (12,471 words) - 22:18, 22 July 2025
(gelatinase) in sebum without any influence in the action of TIMP1 and TIMP2 (the tissue inhibitors of metalloproteases).[unreliable medical source?]...
73 KB (7,302 words) - 05:20, 15 July 2025
inhibitors to the matrix metalloproteinases. There are four TIMPs; TIMP1, TIMP2, TIMP3 and TIMP4. TIMP3 has been observed progressively downregulated in...
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Q3ZCQ8 16708 TIMMDC1 HGNC:1321 Q9NPL8 16709 TIMP1 HGNC:11820 P01033 16710 TIMP2 HGNC:11821 P16035 16711 TIMP3 HGNC:11822 P35625 16712 TIMP4 HGNC:11823 Q99727...
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activator protein, SYNJ2BP. Tat, Thrombin, THBS1, Thrombospondin 2, TIMP1, TIMP2, TIMP3, Tissue factor pathway inhibitor, PLAT, Transforming growth factor-β...
32 KB (3,451 words) - 07:50, 15 July 2025
invasion and metastasis. MMP2 has been shown to interact with: CCL7, THBS2, TIMP2, TIMP4, and Thrombospondin 1. GRCh38: Ensembl release 89: ENSG00000087245...
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worse prognosis of various tumors, such as laryngeal carcinoma or melanoma. TIMP2, TIMP3, TIMP4 GRCh38: Ensembl release 89: ENSG00000102265 – Ensembl, May...
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the distal tubular regions, there is an elevation of the expression of TIMP2 and IGFBP7 and this is linked to early tubular damage in ischemic injury...
40 KB (4,566 words) - 18:09, 23 May 2025
endometrial tissue remodeling. TIMP4 has been shown to interact with MMP2. TIMP1, TIMP2, TIMP3 GRCh38: Ensembl release 89: ENSG00000157150 – Ensembl, May 2017 GRCm38:...
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with the autosomal dominant disorder Sorsby's fundus dystrophy. TIMP1, TIMP2, TIMP4 GRCh38: Ensembl release 89: ENSG00000100234 – Ensembl, May 2017 GRCm38:...
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on 17q (RP17): fine localization to 17q22 and exclusion of the PDEG and TIMP2 genes". Hum. Genet. 101 (1): 13–7. doi:10.1007/s004390050577. PMID 9385361...
11 KB (1,422 words) - 00:30, 24 July 2025
depending on cancer type and context. MMP14 has been shown to interact with TIMP2. Matrix metalloproteinase ARK5 GRCh38: Ensembl release 89: ENSG00000157227...
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AV, Pugacheva EN (2014). "NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis". Mol. Cancer Res. 12 (1): 69–81. doi:10...
64 KB (8,014 words) - 05:12, 28 July 2025