• In enzymology, a thymine dioxygenase (EC 1.14.11.6) is an enzyme that catalyzes the chemical reaction thymine + 2-oxoglutarate + O2 ⇌ {\displaystyle \rightleftharpoons...
    3 KB (251 words) - 16:03, 26 August 2023
  • dependencies of the sequential alpha-ketoglutarate dioxygenase reactions catalyzed by an essentially homogeneous thymine 7-hydroxylase from Rhodotorula glutinis"...
    3 KB (246 words) - 15:38, 26 August 2023
  • Thumbnail for Tet methylcytosine dioxygenase 2
    Tet methylcytosine dioxygenase 2 (TET2) is a human gene. It resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral...
    25 KB (2,576 words) - 13:09, 21 January 2024
  • 6 thymine dioxygenase EC 1.14.11.6: thymine dioxygenase EC 1.14.11.7: procollagen-proline 3-dioxygenase EC 1.14.11.8: trimethyllysine dioxygenase EC...
    189 KB (24,607 words) - 23:55, 9 February 2024
  • Thumbnail for Tet methylcytosine dioxygenase 1
    Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function...
    17 KB (1,893 words) - 03:46, 22 January 2024
  • Thumbnail for Reactive oxygen species
    5hmC to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). Thymine-DNA glycosylase (TDG) recognizes the intermediate bases 5fC and 5caC and...
    73 KB (8,480 words) - 17:09, 1 April 2024
  • Thumbnail for Tet methylcytosine dioxygenase 3
    Tet methylcytosine dioxygenase 3 is a protein that in humans is encoded by the TET3 gene. Tet3 and its respective protein TET 3 are members of the TET...
    12 KB (1,565 words) - 18:54, 20 February 2024
  • Thumbnail for Base excision repair
    and hydrolysis of 5-methylcytosine to thymine, producing G:U and G:T base pairs. If the improper uracils or thymines in these base pairs are not removed...
    29 KB (3,489 words) - 15:28, 28 February 2024
  • 2-nitropropane dioxygenase - 2-oxobutyrate synthase - (2,3-dihydroxybenzoyl)adenylate synthase - 2,4-Dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase - 2010107G12Rik...
    22 KB (1,928 words) - 20:22, 8 April 2024
  • indicates the central roles of ten-eleven translocation methylcytosine dioxygenases (TETs) in the demethylation of 5-methylcytosine to form cytosine. As...
    49 KB (5,387 words) - 17:07, 6 April 2024
  • Thumbnail for CpG site
    regulation that is called epigenetics. Methylated cytosines often mutate to thymines. In humans, about 70% of promoters located near the transcription start...
    51 KB (5,474 words) - 16:32, 19 April 2024
  • Thumbnail for DNA demethylation
    demethylation. These are a ten-eleven translocation methylcytosine dioxygenase (TET) and thymine-DNA glycosylase (TDG). One particular TET enzyme, TET1, and...
    42 KB (5,154 words) - 13:37, 14 February 2024
  • has also recently been indicated, since GADD45 physically interacts with thymine-DNA glycosylase (TDG) and GADD45 may promote the activity of TDG in its...
    52 KB (6,235 words) - 15:49, 26 April 2024
  • Thumbnail for TET enzymes
    demethylation. These are a ten-eleven translocation (TET) methylcytosine dioxygenase and thymine-DNA glycosylase (TDG). One particular TET enzyme, TET1, and TDG...
    32 KB (3,984 words) - 05:42, 27 April 2024
  • Thumbnail for FTO gene
    obesity-associated protein also known as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on...
    35 KB (3,884 words) - 09:59, 27 March 2024
  • Thumbnail for 5-Methylcytosine
    nucleic acid was found to be unusual, in that it contained in addition to thymine, guanine and cytosine, a methylated nucleotide. In 1925, Johnson and Coghill...
    22 KB (2,598 words) - 17:10, 28 March 2024
  • (in volts versus NHE) are guanine 1.29, adenine 1.42, cytosine 1.6 and thymine 1.7. About 1 in 40,000 guanines in the genome are present as 8-oxo-dG under...
    40 KB (4,790 words) - 11:12, 24 March 2024
  • Thumbnail for 8-Oxo-2'-deoxyguanosine
    5hmC to generate 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). Thymine-DNA glycosylase (TDG) recognizes the intermediate bases 5fC and 5caC and...
    25 KB (2,763 words) - 21:16, 13 April 2024
  • Thumbnail for Citric acid cycle
    facilitate reactions via alpha-ketoglutarate in alpha-ketoglutarate-dependent dioxygenases. This mutation results in several important changes to the metabolism...
    56 KB (6,045 words) - 12:06, 20 May 2024
  • are nine human homologs of AlkB. They are: Alkb homolog 1, histone h2a dioxygenase, ALKBH2, ALKBH3, ALKBH4, AlkB homolog 5, RNA demethylase, ALKBH6, ALKBH7...
    12 KB (1,337 words) - 16:19, 4 January 2024
  • cysteine dioxygenase MeSH D08.811.682.690.416.326 – homogentisate 1,2-dioxygenase MeSH D08.811.682.690.416.328 – 3-hydroxyanthranilate 3,4-dioxygenase MeSH D08...
    158 KB (15,232 words) - 06:41, 8 March 2024