Total synthesis, a specialized area within organic chemistry, focuses on constructing complex organic compounds, especially those found in nature, using...
22 KB (2,203 words) - 21:09, 12 March 2025
Diverted total synthesis in chemistry is a strategy in drug discovery aiming at organic synthesis of natural product analogues rather than the natural...
6 KB (619 words) - 19:44, 27 October 2022
The total synthesis of the complex biomolecule vitamin B12 was accomplished in two different approaches by the collaborating research groups of Robert...
132 KB (7,466 words) - 06:37, 11 March 2025
Strychnine total synthesis in chemistry describes the total synthesis of the complex biomolecule strychnine. The first reported method by the group of...
39 KB (4,087 words) - 03:50, 29 February 2024
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an...
16 KB (1,961 words) - 04:43, 8 August 2024
Holton Taxol total synthesis, published by Robert A. Holton and his group at Florida State University in 1994, was the first total synthesis of Taxol (generic...
16 KB (1,478 words) - 23:58, 18 February 2025
The total synthesis of quinine, a naturally-occurring antimalarial drug, was developed over a 150-year period. The development of synthetic quinine is...
18 KB (2,189 words) - 22:28, 19 March 2025
Oseltamivir total synthesis concerns the total synthesis of the anti-influenza drug oseltamivir marketed by Hoffmann-La Roche under the trade name Tamiflu...
20 KB (2,311 words) - 18:00, 17 January 2025
The Nicolaou Taxol total synthesis, published by K. C. Nicolaou and his group in 1994 concerns the total synthesis of taxol. Taxol is an important drug...
18 KB (1,520 words) - 17:15, 19 January 2024
The Danishefsky Taxol total synthesis in organic chemistry is an important third Taxol synthesis published by the group of Samuel Danishefsky in 1996 two...
15 KB (1,399 words) - 13:35, 26 August 2024
Synthesis of morphine-like alkaloids in chemistry describes the total synthesis of the natural morphinan class of alkaloids that includes codeine, morphine...
10 KB (948 words) - 02:44, 27 December 2023
The article concerns the total synthesis of galanthamine, a drug used for the treatment of mild to moderate Alzheimer's disease. The natural source of...
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organic synthesis, there are many different types of synthetic routes that can be completed including total synthesis, stereoselective synthesis, automated...
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Natural product (redirect from Natural product synthesis)
Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis and have played a central role in the development...
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Wender Taxol total synthesis in organic chemistry describes a Taxol total synthesis (one of six to date) by the group of Paul Wender at Stanford University...
9 KB (1,098 words) - 07:53, 11 June 2024
Electrosynthesis Methods in Organic Synthesis Organic synthesis Peptide synthesis Total synthesis Automated synthesis Vogel, A.I.; Tatchell, A.R.; Furnis...
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Cholesterol total synthesis in chemistry describes the total synthesis of the complex biomolecule cholesterol and is considered a great scientific achievement...
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Steroid (redirect from Steroid synthesis)
industry. Some steroidal hormones are economically obtained only by total synthesis from petrochemicals (e.g. 13-alkyl steroids). For example, the pharmaceutical...
84 KB (8,672 words) - 05:14, 5 May 2025
Diels–Alder reaction (redirect from Diene synthesis)
Grzejszczak, S. (1987). "General strategies for the synthesis of indole alkaloids. Total synthesis of (±)-reserpine and (±)-α-yohimbine". Journal of the...
69 KB (7,937 words) - 13:38, 5 April 2025
Aflatoxin total synthesis concerns the total synthesis of a group of organic compounds called aflatoxins. These compounds occur naturally in several fungi...
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Α-Amanitin (section Total synthesis)
the desired bio-reactive (R)-enantiomer sulfoxide, completing the total synthesis.[citation needed] α-Amanitin has an unusually strong and specific attraction...
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the total synthesis of akuammiline natural products. The method has also been used in medicinal chemistry. Indometacin preparation. Triptan synthesis Iprindole...
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group tolerance. The Negishi coupling finds common use in the field of total synthesis as a method for selectively forming C-C bonds between complex synthetic...
35 KB (4,130 words) - 08:53, 14 May 2025
convergent synthesis is a strategy that aims to improve the efficiency of multistep synthesis, most often in organic synthesis. In this type of synthesis several...
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Gesamtkunstwerk (redirect from Synthesis of the arts)
Gesamtkunstwerk (German: [ɡəˈzamtˌkʊnstvɛʁk] , 'total work of art', 'ideal work of art', 'universal artwork', 'synthesis of the arts', 'comprehensive artwork',...
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strain in the conformation of the molecule. In the seminar paper on the total synthesis of (+)-monensin, Kishi and co-workers utilized the allylic strain to...
21 KB (2,486 words) - 10:37, 15 March 2025
transition metals and has found numerous applications in chemical and total synthesis. Chiral ligands can be used to render the reaction asymmetric, constructing...
10 KB (1,283 words) - 23:50, 31 August 2024
The Paal–Knorr synthesis is a reaction used to synthesize substituted furans, pyrroles, or thiophenes from 1,4-diketones. It is a synthetically valuable...
15 KB (1,625 words) - 14:45, 31 March 2025
The Stille reaction is a chemical reaction widely used in organic synthesis. The reaction involves the coupling of two organic groups, one of which is...
47 KB (5,493 words) - 02:16, 16 May 2025
contiguous stereocenters. Azomethine ylides thus have high utility in total synthesis, and formation of chiral ligands and pharmaceuticals. Azomethine ylides...
18 KB (1,988 words) - 01:46, 19 April 2024