normal human cells, trans-splicing can also be the mechanism behind certain oncogenic fusion transcripts. Spliced leader (SL) trans-splicing is used by certain...

of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...

on how they splice themselves out, they can be classified into cis-splicing (which means that they splice themselves out) or trans-splicing (which means...

Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...

into single gene mRNAs, and in others to splice onto monocistronic transcripts. The major role of trans-splicing on monocistronic transcripts is largely...

Alternative splicing generally describes a tightly regulated process in which alternative transcripts are intentionally generated by the splicing machinery...

on two different chromosomes. Trans-splicing is very common in C. elegans A splice donor site being joined to a splice acceptor site further upstream...

performed is the splicing of introns which are sequences in the transcribed region that do not encode a protein. Alternative splicing mechanisms can result...

and trypanosomes make extensive use of trans-splicing to generate chimeric RNAs. In these organisms, splicing reactions between a protein coding RNA and...

content and a splice acceptor site that is the signal for trans-splicing. Such a trans-splice site is essentially defined as an acceptor (3') splice site without...

inhibiting gene expression, splicing ribozymes can be used to repair damaged or defective RNA. Splicing ribozymes catalyze RNA splicing, removing a section of...

include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found...

RNA splicing. The term exon refers to both the DNA sequence within a gene and to the corresponding sequence in RNA transcripts. In RNA splicing, introns...

(2006). "The origin and evolution of Archaea: a state of the art". Philos Trans R Soc Lond B Biol Sci. 361 (1470): 1007–22. doi:10.1098/rstb.2006.1841....

peptide segments can be from the same protein (cis-splicing) or different proteins (trans-splicing). The peptides have to be translocated from the cytosol...

Instead, fragments are transcribed and spliced together using their own specialized trans splicing machinery. Once spliced together, the transcript undergoes...

mRNA strand and either translated together in the cytoplasm, or undergo splicing to create monocistronic mRNAs that are translated separately, i.e. several...

immunoglobulin genes. Oncogenic fusion transcripts may also be caused by trans-splicing or read-through events. Since chromosomal translocations play such a...

non-coding RNA involved in trans-splicing in lower eukaryotes. Trans-splicing is a form of RNA processing. The acquisition of a spliced leader from an SL RNA...

"What is Uterine Sarcoma?". Li H, et al. (2009). "Gene fusion and RNA trans-splicing in normal and neoplastic cells". Cell Cycle. 8 (2): 218–222. doi:10...

2006-11-21. Houseley J, Tollervey D (August 2010). "Apparent non-canonical trans-splicing is generated by reverse transcriptase in vitro". PLOS ONE. 5 (8): e12271...

from host transcripts; these are called self-splicing RNAs. There are two main groups of self-splicing RNAs: group I catalytic intron and group II catalytic...

located close to a small intron that is spliced in males, but kept in females through splicing inhibition. This splicing inhibition is maintained by Sxl. When...

RNA trans-splicing (SMaRT) have been evaluated for MYBPC3. Exon skipping can be achieved using antisense oligonucleotide (AON) masking exonic splicing enhancer...

Notable characteristics of trypanosomatids are the ability to perform trans-splicing of RNA and possession of glycosomes, where much of their glycolysis...

made much more complicated by features like (cis-) alternative splicing, trans-splicing, single-nucleotide polymorphism, and post-transcriptional modification...

RNA encoded by a fusion gene or by two different genes by subsequent trans-splicing. Certain fusion transcripts are commonly produced by cancer cells, and...

abundance of alternative splicing, which occurs in most human genes, and the specificity in which splicing is carried out in vivo. Splicing is distinctly conducted...

species of nematode worms. They are thought to be involved in mRNA trans-splicing. SmY RNAs are about 70–90 nucleotides long and share a common secondary...

"How chromosomal translocations arise to cause cancer: Gene proximity, trans-splicing, and DNA end joining". iScience. 26 (6): 106900. Bibcode:2023iSci.....