molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information...
75 KB (8,351 words) - 22:53, 24 June 2025
General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific...
12 KB (1,319 words) - 16:40, 17 July 2025
Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...
46 KB (5,537 words) - 04:52, 15 July 2025
by an inactive transcription factor. Phosphorylation of the transcription factor may activate it and that activated transcription factor may then activate...
58 KB (6,891 words) - 17:39, 22 July 2025
Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene...
30 KB (3,441 words) - 08:44, 5 February 2025
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded...
43 KB (4,822 words) - 21:59, 15 July 2025
Cis-regulatory element (redirect from Transcription factor-binding site)
regulate. CREs typically regulate gene transcription by binding to transcription factors. A single transcription factor may bind to many CREs, and hence control...
30 KB (3,469 words) - 01:44, 6 July 2025
biology. The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working...
61 KB (7,316 words) - 02:39, 22 July 2025
This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. It was assembled by manual curation. More detailed...
374 KB (81 words) - 11:17, 3 January 2025
The fluffy (fl) gene of Neurospora crassa is required for asexual sporulation and encodes an 88 kDa polypeptide containing a typical fungal Zn2Cys6 DNA-binding...
749 bytes (69 words) - 09:01, 2 January 2021
(AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and...
42 KB (4,614 words) - 16:27, 16 July 2025
sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation...
20 KB (2,045 words) - 13:47, 26 May 2025
promoters. General transcription factors are a group of proteins involved in transcription initiation and regulation. These factors typically have DNA-binding...
49 KB (5,867 words) - 00:02, 14 July 2025
T-box transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription...
36 KB (4,178 words) - 20:39, 16 July 2025
Escargot (esg) is a transcription factor expressed in Drosophila melanogaster. It is responsible for the maintenance of intestinal stem cells and is used...
18 KB (1,998 words) - 09:39, 30 June 2025
The Gal4 transcription factor is a positive regulator of gene expression of galactose-induced genes. This protein represents a large fungal family of transcription...
19 KB (2,205 words) - 12:40, 13 August 2023
Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)...
18 KB (2,448 words) - 11:07, 5 February 2025
A ρ factor (Rho factor) is a bacterial protein involved in the termination of transcription. Rho factor binds to the transcription terminator pause site...
6 KB (759 words) - 09:43, 22 May 2025
Transformation Specific) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, 27 in the...
10 KB (1,058 words) - 23:17, 24 May 2025
by regio/stereoselective Michael addition to ring A. NF-κB is a transcription factor that regulates many genes involved in cell survival, growth, immune...
9 KB (765 words) - 22:00, 18 June 2025
molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors. DP forms a heterodimer...
1 KB (117 words) - 19:31, 6 July 2021
Artificial transcription factors (ATFs) are engineered individual or multi molecule transcription factors that either activate or repress gene transcription (biology)...
14 KB (1,698 words) - 16:30, 17 July 2025
Promoter (genetics) (redirect from Transcription promoter)
polymerase and for proteins called transcription factors that recruit RNA polymerase. These transcription factors have specific activator or repressor...
55 KB (6,390 words) - 11:11, 2 June 2025
Transcription factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase...
5 KB (593 words) - 20:14, 3 June 2022
polymerase II active site for transcription. The minimal PIC includes RNA polymerase II and six general transcription factors: TFIIA, TFIIB, TFIID, TFIIE...
11 KB (1,210 words) - 06:00, 28 October 2024
Sex-determining region Y protein (redirect from Testis determining factor)
(SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that...
42 KB (5,183 words) - 18:35, 16 July 2025
STAT3 (category Transcription factors)
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene. It is a member of the...
29 KB (3,485 words) - 06:51, 2 June 2025
TFAM (redirect from Mitochondrial transcription factor A)
Mitochondrial transcription factor A, abbreviated as TFAM or mtTFA, is a protein that in humans is encoded by the TFAM gene. This gene encodes a mitochondrial...
10 KB (1,225 words) - 18:34, 17 July 2025
general transcription factor-δ or basic transcription factor 2 was characterized as an indispensable transcription factor in vitro. This factor was also...
11 KB (1,203 words) - 14:43, 29 April 2025
Addiction (redirect from Risk factors for addiction)
over extended time. DeltaFosB (ΔFosB), a gene transcription factor, is a critical component and common factor in the development of virtually all forms of...
206 KB (23,805 words) - 20:22, 18 July 2025