• Transcriptome instability is a genome-wide, pre-mRNA splicing-related characteristic of certain cancers. In general, pre-mRNA splicing is dysregulated...
    4 KB (365 words) - 08:25, 28 October 2024
  • Thumbnail for Alternative splicing
    individual cancers, a phenomenon referred to as transcriptome instability. Transcriptome instability has further been shown to correlate grealty with...
    62 KB (7,817 words) - 22:27, 5 July 2025
  • Thumbnail for DNA (cytosine-5)-methyltransferase 3A
    It has also been found that DNMT3A-mutated cell lines exhibit transcriptome instability, in that they have much more erroneous RNA splicing as compared...
    34 KB (3,924 words) - 10:55, 28 March 2024
  • sequencing platforms to (i) formulate transcriptome dynamics on different time scales, (ii) measure the instability of cell states, and (iii) identify developmental...
    8 KB (898 words) - 10:34, 10 December 2024
  • Thumbnail for Helicobacter pylori
    Single-cell transcriptomics using single-cell RNA-Seq gave the complete transcriptome of H. pylori which was published in 2010. This analysis of its transcription...
    150 KB (16,798 words) - 21:22, 30 June 2025
  • that allows for the investigation of phenotypes at the level of the transcriptome, to elucidate gene functions in many cells, in a massively parallel...
    22 KB (2,704 words) - 08:52, 3 June 2025
  • Thumbnail for Slime mold
    multicellularity revealed by the Acrasis kona genome and developmental transcriptomes, doi:10.21203/rs.3.rs-2587723/v1 Gilbert, H. C.; Martin, G. W. (1933)...
    55 KB (5,616 words) - 18:08, 12 July 2025
  • Thumbnail for Pseudouridine
    PMID 8373778. Kalsotra, Auinash (2016-11-02). "Faculty of 1000 evaluation for Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation...
    26 KB (2,907 words) - 03:03, 2 June 2025
  • Thumbnail for Epstein–Barr virus
    Klichinsky M, et al. (August 2012). "An atlas of the Epstein–Barr virus transcriptome and epigenome reveals host-virus regulatory interactions". Cell Host...
    65 KB (6,795 words) - 20:50, 9 July 2025
  • Baas F, Riggins G, van Sluis P, et al. (February 2001). "The human transcriptome map: clustering of highly expressed genes in chromosomal domains". Science...
    20 KB (2,188 words) - 14:11, 19 June 2025
  • Thumbnail for Colorectal cancer
    Bidkhori G, et al. (August 2017). "A pathology atlas of the human cancer transcriptome". Science. 357 (6352): eaan2507. doi:10.1126/science.aan2507. PMID 28818916...
    154 KB (16,761 words) - 07:25, 12 July 2025
  • (December 2022). "Aging is associated with a systemic length-associated transcriptome imbalance". Nature Aging. 2 (12): 1191–1206. doi:10.1038/s43587-022-00317-6...
    58 KB (7,259 words) - 18:59, 29 June 2025
  • Sugano S (March 2011). "Ultraconserved cDNA segments in the human transcriptome exhibit resistance to folding and implicate function in translation...
    50 KB (4,445 words) - 16:28, 20 February 2025
  • Thumbnail for Telomeric repeat–containing RNA
    transcripts have also been identified as part of the yeast telomeric transcriptome: a transcript complementary to the 5' subtelomeric sequence known as...
    46 KB (5,239 words) - 10:15, 24 June 2025
  • Thumbnail for Infectious causes of cancer
    discovered KSHV/HHV-8 in 1994, using a new technology called digital transcriptome subtraction. About 80% of Merkel cell carcinomas are caused by Merkel...
    44 KB (5,214 words) - 04:44, 12 July 2025
  • Thumbnail for Chromosomal rearrangement
    African cassava cultivar reveal novel pan-genome and allele-specific transcriptome features". GigaScience. 11. doi:10.1093/gigascience/giac028. PMC 8952263...
    7 KB (771 words) - 20:30, 29 June 2024
  • Thumbnail for Oncovirus
    computer subtraction of human sequences from a tumor transcriptome, called digital transcriptome subtraction (DTS). DTS was used to isolate DNA fragments...
    52 KB (6,087 words) - 01:50, 7 February 2025
  • Thumbnail for Adolescence
    ; Zalsman G.; John J. Mann; Chechik G. (2014). "Transitions in the transcriptome of the serotonergic and dopaminergic systems in the human brain during...
    178 KB (22,000 words) - 01:46, 24 June 2025
  • Thumbnail for Human papillomavirus infection
    carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes". Nature Genetics. 52 (8): 800–810. doi:10.1038/s41588-020-0673-7...
    150 KB (16,334 words) - 01:01, 14 July 2025
  • Thumbnail for Streptomyces
    although it is often referred to as S. coelicolor for convenience. The transcriptome and translatome analyses of the strain A3(2) were published in 2016...
    38 KB (3,756 words) - 13:41, 12 July 2025
  • contigs still need to be assembled. Transcriptomics is the study of the transcriptome, usually by characterizing the relative abundances of messenger RNA...
    33 KB (4,024 words) - 23:03, 6 June 2025
  • Thumbnail for Primary transcript
    expand. cis-splicing Outron trans-splicing Transcription (biology) Transcriptome Strachan T, Read AP (January 2004). Human Molecular Genetics 3. Garland...
    22 KB (2,668 words) - 08:52, 16 December 2024
  • The Trinity software for RNA-seq, in comparison with other de novo transcriptome assemblers, was reported to recover more full-length transcripts over...
    33 KB (4,188 words) - 15:44, 5 March 2024
  • (contrib.) Single cell data enables dissecting cell types present in bulk transcriptome data, 2024; (contrib.) Generation of two Alpha-I antitrypsin deficiency...
    11 KB (939 words) - 17:22, 12 May 2025
  • Thumbnail for Polymerase chain reaction
    primers (probes) to amplify DNA sequences from a sequenced genome or transcriptome. In silico PCR was proposed as an educational tool for molecular biology...
    92 KB (11,424 words) - 17:30, 11 July 2025
  • evolution as a model, and genome chaos, an overarching phenomenon of genomic instability that results from stress and can rearrange the genome, characterized...
    15 KB (1,665 words) - 01:34, 24 May 2025
  • During II, TCGA was able to begin performing whole exome and whole transcriptome sequencing on all cases and whole genome sequencing on 10% of the cases...
    82 KB (7,468 words) - 14:00, 3 March 2025
  • Thumbnail for Oncogenomics
    molecular-cytogenetic tumor data. Oncomine has compiled data from cancer transcriptome profiles. The integrative oncogenomics database IntOGen and the Gitools...
    66 KB (7,684 words) - 22:49, 25 April 2024
  • binding proteins may regulate post transcriptionally large amount of the transcriptome, the targeting of a single gene is of interest to the scientific community...
    27 KB (3,383 words) - 01:17, 8 September 2024
  • Investigators can analyze genome, methylome, epigenome, metabolome, transcriptome, proteome, microbiome, immunity and interactome. A putative risk factor...
    26 KB (1,946 words) - 04:28, 9 June 2025