Transcriptome instability is a genome-wide, pre-mRNA splicing-related characteristic of certain cancers. In general, pre-mRNA splicing is dysregulated...
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individual cancers, a phenomenon referred to as transcriptome instability. Transcriptome instability has further been shown to correlate grealty with...
62 KB (7,817 words) - 22:27, 5 July 2025
It has also been found that DNMT3A-mutated cell lines exhibit transcriptome instability, in that they have much more erroneous RNA splicing as compared...
34 KB (3,924 words) - 10:55, 28 March 2024
sequencing platforms to (i) formulate transcriptome dynamics on different time scales, (ii) measure the instability of cell states, and (iii) identify developmental...
8 KB (898 words) - 10:34, 10 December 2024
Helicobacter pylori (section Transcriptome)
Single-cell transcriptomics using single-cell RNA-Seq gave the complete transcriptome of H. pylori which was published in 2010. This analysis of its transcription...
150 KB (16,798 words) - 21:22, 30 June 2025
that allows for the investigation of phenotypes at the level of the transcriptome, to elucidate gene functions in many cells, in a massively parallel...
22 KB (2,704 words) - 08:52, 3 June 2025
multicellularity revealed by the Acrasis kona genome and developmental transcriptomes, doi:10.21203/rs.3.rs-2587723/v1 Gilbert, H. C.; Martin, G. W. (1933)...
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PMID 8373778. Kalsotra, Auinash (2016-11-02). "Faculty of 1000 evaluation for Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation...
26 KB (2,907 words) - 03:03, 2 June 2025
Klichinsky M, et al. (August 2012). "An atlas of the Epstein–Barr virus transcriptome and epigenome reveals host-virus regulatory interactions". Cell Host...
65 KB (6,795 words) - 20:50, 9 July 2025
Baas F, Riggins G, van Sluis P, et al. (February 2001). "The human transcriptome map: clustering of highly expressed genes in chromosomal domains". Science...
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Bidkhori G, et al. (August 2017). "A pathology atlas of the human cancer transcriptome". Science. 357 (6352): eaan2507. doi:10.1126/science.aan2507. PMID 28818916...
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(December 2022). "Aging is associated with a systemic length-associated transcriptome imbalance". Nature Aging. 2 (12): 1191–1206. doi:10.1038/s43587-022-00317-6...
58 KB (7,259 words) - 18:59, 29 June 2025
Sugano S (March 2011). "Ultraconserved cDNA segments in the human transcriptome exhibit resistance to folding and implicate function in translation...
50 KB (4,445 words) - 16:28, 20 February 2025
Telomeric repeat–containing RNA (section Immunodeficiency, Centromeric Region Instability, Facial Anomalies (ICF Syndrome))
transcripts have also been identified as part of the yeast telomeric transcriptome: a transcript complementary to the 5' subtelomeric sequence known as...
46 KB (5,239 words) - 10:15, 24 June 2025
discovered KSHV/HHV-8 in 1994, using a new technology called digital transcriptome subtraction. About 80% of Merkel cell carcinomas are caused by Merkel...
44 KB (5,214 words) - 04:44, 12 July 2025
African cassava cultivar reveal novel pan-genome and allele-specific transcriptome features". GigaScience. 11. doi:10.1093/gigascience/giac028. PMC 8952263...
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computer subtraction of human sequences from a tumor transcriptome, called digital transcriptome subtraction (DTS). DTS was used to isolate DNA fragments...
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; Zalsman G.; John J. Mann; Chechik G. (2014). "Transitions in the transcriptome of the serotonergic and dopaminergic systems in the human brain during...
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carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes". Nature Genetics. 52 (8): 800–810. doi:10.1038/s41588-020-0673-7...
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although it is often referred to as S. coelicolor for convenience. The transcriptome and translatome analyses of the strain A3(2) were published in 2016...
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contigs still need to be assembled. Transcriptomics is the study of the transcriptome, usually by characterizing the relative abundances of messenger RNA...
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expand. cis-splicing Outron trans-splicing Transcription (biology) Transcriptome Strachan T, Read AP (January 2004). Human Molecular Genetics 3. Garland...
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The Trinity software for RNA-seq, in comparison with other de novo transcriptome assemblers, was reported to recover more full-length transcripts over...
33 KB (4,188 words) - 15:44, 5 March 2024
(contrib.) Single cell data enables dissecting cell types present in bulk transcriptome data, 2024; (contrib.) Generation of two Alpha-I antitrypsin deficiency...
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primers (probes) to amplify DNA sequences from a sequenced genome or transcriptome. In silico PCR was proposed as an educational tool for molecular biology...
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evolution as a model, and genome chaos, an overarching phenomenon of genomic instability that results from stress and can rearrange the genome, characterized...
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During II, TCGA was able to begin performing whole exome and whole transcriptome sequencing on all cases and whole genome sequencing on 10% of the cases...
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Oncogenomics (section Transcriptomes)
molecular-cytogenetic tumor data. Oncomine has compiled data from cancer transcriptome profiles. The integrative oncogenomics database IntOGen and the Gitools...
66 KB (7,684 words) - 22:49, 25 April 2024
binding proteins may regulate post transcriptionally large amount of the transcriptome, the targeting of a single gene is of interest to the scientific community...
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Investigators can analyze genome, methylome, epigenome, metabolome, transcriptome, proteome, microbiome, immunity and interactome. A putative risk factor...
26 KB (1,946 words) - 04:28, 9 June 2025