Triphenylethylene (TPE) is the organic compound with the formula (C6H5)2C=CH(C6H5). It is a colorless solid. The compound is prepared in two steps from...
8 KB (761 words) - 13:48, 20 May 2025
first main structural class of SERM-type molecules reported are the triphenylethylenes. The stilbene core (similar to the nonsteroidal estrogen, diethylstilbestrol)...
58 KB (6,598 words) - 18:11, 25 May 2025
Clomifene (category Triphenylethylenes)
of pregnancies carried to viability. Clomifene is a nonsteroidal triphenylethylene derivative that acts as a selective estrogen receptor modulator (SERM)...
48 KB (4,759 words) - 20:23, 29 May 2025
Enclomifene (category Triphenylethylenes)
Name), a nonsteroidal selective estrogen receptor modulator of the triphenylethylene group, acts by antagonizing the estrogen receptor (ER) in the pituitary...
17 KB (1,527 words) - 20:43, 29 May 2025
Tamoxifen (category Triphenylethylenes)
decreasing the growth of breast cancer cells. It is a member of the triphenylethylene group of compounds. Tamoxifen was initially made in 1962, by chemist...
88 KB (9,262 words) - 00:51, 17 February 2025
Tetraarylethylenes and Their Application for the Preparation of [Triphenylethylene−Spacer−Triphenylethylene] Triads". The Journal of Organic Chemistry. 72 (21): 8054–8061...
4 KB (263 words) - 21:42, 25 May 2025
Toremifene (category Triphenylethylenes)
and the uterus and antiestrogenic effects in the breasts. It is a triphenylethylene derivative and is closely related to tamoxifen. Toremifene was introduced...
38 KB (3,532 words) - 22:24, 29 May 2025
Afimoxifene (category Triphenylethylenes)
TamoGel, is a selective estrogen receptor modulator (SERM) of the triphenylethylene group and an active metabolite of tamoxifen. The drug is under development...
7 KB (470 words) - 14:27, 2 May 2025
equivalent, a method of comparing communication satellite bandwidths Triphenylethylene, the parent compound of a group of selective estrogen receptor modulators...
1 KB (186 words) - 23:46, 20 February 2024
Endoxifen (category Triphenylethylenes)
nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group as well as a protein kinase C (PKC) inhibitor. It is under development...
15 KB (1,430 words) - 16:01, 18 January 2025
114 ? ? ? Estrogen Chlorotrianisene TACE 1.74 ? 15.30 ? Estrogen Triphenylethylene TPE 0.074 ? ? ? Estrogen Triphenylbromoethylene TPBE 2.69 ? ? ? Estrogen...
73 KB (7,807 words) - 19:54, 4 June 2025
Norendoxifen (category Triphenylethylenes)
N-didesmethyltamoxifen, is a nonsteroidal aromatase inhibitor (AI) of the triphenylethylene group that was never marketed. It is an active metabolite of the selective...
4 KB (207 words) - 18:03, 21 October 2024
triphenylethanol and was derived from chlorotrianisene (TACE), a nonsteroidal triphenylethylene estrogen. The nonsteroidal triphenylethanol antiestrogen ethamoxytriphetol...
7 KB (574 words) - 17:03, 18 April 2025
were actually originally derived). The triphenylethylene group of estrogenic drugs that includes triphenylethylene itself, estrobin, chlorotrianisene, broparestrol...
7 KB (521 words) - 14:39, 12 March 2025
nonsteroidal selective estrogen receptor modulator (SERM) related to triphenylethylenes like tamoxifen that was never marketed. It is a mixture of (E)- and...
4 KB (219 words) - 15:19, 18 January 2025
Broparestrol (category Triphenylethylenes)
nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that has been used in Europe as a dermatological agent and for...
6 KB (410 words) - 20:56, 24 May 2025
Estrobin (category Triphenylethylenes)
abbreviated as DBE, is a synthetic, nonsteroidal estrogen of the triphenylethylene group that was never marketed. Chlorotrianisene, and subsequently...
3 KB (135 words) - 15:37, 18 January 2025
Chlorotrianisene (category Triphenylethylenes)
triphenylethylene series to be introduced. CTA was derived from estrobin (DBE), a derivative of the very weakly estrogenic compound triphenylethylene...
18 KB (1,502 words) - 15:08, 19 January 2025
Nafoxidine (category Triphenylethylenes)
estrogen receptor modulator (SERM) or partial antiestrogen of the triphenylethylene group that was developed for the treatment of advanced breast cancer...
6 KB (459 words) - 21:49, 27 May 2025
Droloxifene (category Triphenylethylenes)
nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was developed originally in Germany and later in Japan...
8 KB (531 words) - 05:58, 26 May 2025
Zuclomifene (category Triphenylethylenes)
nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was never marketed. It is one of the two stereoisomers...
4 KB (227 words) - 02:01, 7 March 2025
256.34 g/mol) may refer to: 7,12-Dimethylbenz[a]anthracene (DMBA) Triphenylethylene This set index page lists chemical structure articles associated with...
321 bytes (54 words) - 01:31, 14 November 2021
114 ? ? ? Estrogen Chlorotrianisene TACE 1.74 ? 15.30 ? Estrogen Triphenylethylene TPE 0.074 ? ? ? Estrogen Triphenylbromoethylene TPBE 2.69 ? ? ? Estrogen...
69 KB (7,809 words) - 22:35, 29 May 2025
derivative. Allenolic acid Diethylstilbestrol Stilbestrol Chlorotrianisene Triphenylethylene Hill RA, Makin HL, Kirk DN, Murphy GM (23 May 1991). Dictionary of...
6 KB (463 words) - 15:49, 2 May 2024
114 ? ? ? Estrogen Chlorotrianisene TACE 1.74 ? 15.30 ? Estrogen Triphenylethylene TPE 0.074 ? ? ? Estrogen Triphenylbromoethylene TPBE 2.69 ? ? ? Estrogen...
35 KB (3,874 words) - 23:30, 22 May 2025
to triphenylethylene SERMs like clomifene and tamoxifen. It has been referred to as a diphenylethylene derivative, differing from triphenylethylenes only...
14 KB (1,158 words) - 15:04, 19 January 2025
structural formula of (C 6H 5) 2C(OH)CH 2C 6H 5, and is related to triphenylethylene, from which it can be prepared by hydration. It is the structural...
2 KB (190 words) - 10:26, 1 March 2024
selective estrogen receptor modulators (SERMs) are nonsteroidal, with triphenylethylenes like tamoxifen and clomifene having been derived from DES, and these...
7 KB (563 words) - 21:46, 24 November 2024
a benzothiophene derivative and is structurally distinct from the triphenylethylene SERMs like tamoxifen, clomifene, and toremifene. It is the only benzothiophene...
46 KB (4,767 words) - 22:02, 29 May 2025
Clomifenoxide (category Triphenylethylenes)
nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and...
3 KB (135 words) - 15:05, 19 January 2025