conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. The...
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A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...
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Ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step in the ubiquitination reaction...
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Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a...
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Proteasome (redirect from Ubiquitin proteosome system)
the Ubiquitin-activating enzyme (E1), Ubiquitin-conjugating enzyme (E2), and ubiquitin ligases (E3). Once a protein is tagged with a single ubiquitin molecule...
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CDC34 (redirect from Ubiquitin-conjugating enzyme E2 R1)
humans encodes the protein Ubiquitin-conjugating enzyme E2 R1. This protein is a member of the ubiquitin-conjugating enzyme family, which catalyzes the...
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ubiquitination machinery; ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin ligases (E3s). The result is ubiquitin bound to lysine...
37 KB (4,317 words) - 07:27, 24 January 2025
Ubiquitin conjugating enzyme E2 Q2 is a protein that in humans is encoded by the UBE2Q2 gene. GRCh38: Ensembl release 89: ENSG00000140367 – Ensembl, May...
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is then transferred to an E2 ubiquitin-conjugating enzyme before being conjugated to the target protein via an E3 ubiquitin ligase. There exists a multitude...
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UBE3A (redirect from Ubiquitin protein ligase E3A)
Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene. This...
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Ubiquitin conjugating enzyme E2 F (putative) is a protein that in humans is encoded by the UBE2F gene. GRCh38: Ensembl release 89: ENSG00000184182 – Ensembl...
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marrow stem cells of patients presenting with VEXAS. E: The E1 ubiquitin conjugating enzyme encoded by the UBA1 gene is mutated in patients. X: The mutated...
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SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene. It is also sometimes referred to as "ubiquitin conjugating enzyme E2I"...
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Ubiquitin-conjugating enzyme E2 A is a protein that in humans is encoded by the UBE2A gene. The modification of proteins with ubiquitin is an important...
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Endoplasmic-reticulum-associated protein degradation (section Ubiquitin-dependent degradation by the proteasome)
C-terminus of ubiquitin. The resulting activated ubiquitin is then passed to E2, which is a ubiquitin-conjugating enzyme. Another group of enzymes, more specifically...
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SUMO protein (redirect from Small ubiquitin-like modifier)
E1 enzyme (SUMO Activating Enzyme (SAE)) which is a heterodimer (subunits SAE1 and SAE2). It is then passed to an E2, which is a conjugating enzyme (Ubc9)...
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Ubiquitin-conjugating enzyme E2 variant 1 is a protein that in humans is encoded by the UBE2V1 gene. Ubiquitin-conjugating E2 enzyme variant proteins constitute...
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SCF complex (redirect from SCF ubiquitin ligase complex)
bringing the target protein into proximity with the functional E2 ubiquitin-conjugating enzyme. FBP is also essential in regulating SCF activity during the...
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Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene. The protein encoded by this gene belongs to the ubiquitin-conjugating...
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CBL (gene) (redirect from Cbl ubiquitin ligase)
E3 ubiquitin-protein ligase CBL is an enzyme that is humans is encoded by the CBL (Casitas B-lineage Lymphoma) gene. CBL gene is the founding member the...
34 KB (3,869 words) - 01:59, 9 June 2025
States University Baptist Church (disambiguation) Ubiquitin C, a human gene Ubiquitin-conjugating enzyme Unipolar brush cell, a class of excitatory glutamatergic...
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Varshavsky, A. (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329: 131-134. doi:10.1038/329131a0. 7. Johnson, E. S...
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Ubiquitin-conjugating enzyme E2 G2 is a protein that in humans is encoded by the UBE2G2 gene. The modification of proteins with ubiquitin is an important...
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enzymes (E1); conjugation, performed by ubiquitin-conjugating enzymes (E2); and ligation, performed by ubiquitin ligases (E3). The result of this process...
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Ubiquitin-conjugating enzyme E2 C is a protein that in humans is encoded by the UBE2C gene. The modification of proteins with ubiquitin is an important...
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Cullin (section Cullin-RING ubiquitin ligases)
The RING protein appears to function as a docking site for ubiquitin-conjugating enzymes (E2s). Other proteins contain a cullin-homology domain, such...
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UBE2Z (category Enzymes)
Ubiquitin conjugating enzyme E2 Z (UBE2Z), also known as UBA6-specific E2 enzyme 1 (USE1), is an enzyme that in humans is encoded by the UBE2Z gene on...
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dehydrogenase and ubiquitin conjugating enzyme were up-regulated in the presence of microcystins in the food of D. magna and with this the enzymes of glycolysis...
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Ubiquitin-conjugating enzyme E2 variant 2 is a protein that in humans is encoded by the UBE2V2 gene. Ubiquitin-conjugating enzyme E2 variant proteins...
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Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the UBE2D2 gene. Modifying proteins with ubiquitin is an important cellular...
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