Vicinal difunctionalization refers to a chemical reaction involving transformations at two adjacent centers (most commonly carbons). This transformation...

2-relationship). It may arise from vicinal difunctionalization. For example, the molecule 2,3-dibromobutane carries two vicinal bromine atoms and 1,3-dibromobutane...

keto-enol tautomerism to the saturated carbonyl compound. In vicinal difunctionalization the proton is replaced by another electrophile. Conjugated carbonyls...