5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene. The 5-HT1B receptor is a 5-HT...
23 KB (2,513 words) - 10:28, 14 April 2025
which activates 5-HT1A, 5-HT1D, 5-HT1B, D2 and norepinephrine receptors. LSD (a psychedelic) is a 5-HT1A, 5-HT2A, 5-HT2C, 5-HT5A and 5-HT6 agonist. The...
65 KB (5,273 words) - 08:55, 28 May 2025
on this receptor. Serenics such as batoprazine, eltoprazine, and fluprazine are agonists of the 5-HT1B receptor and other serotonin receptors, and have...
16 KB (1,664 words) - 07:32, 20 February 2025
chamber) as well. Conversely, the serotonin 5-HT1B receptor antagonist GR-55562 and the serotonin 5-HT2A receptor antagonist ketanserin were both ineffective...
70 KB (6,753 words) - 20:18, 7 June 2025
Zolmitriptan (category 5-HT1B agonists)
pressure, and dry mouth. The drug acts as a selective serotonin 5-HT1B and 5-HT1D receptor agonist. Structurally, it is a triptan and a tryptamine derivative...
28 KB (2,503 words) - 19:52, 28 May 2025
functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity"...
11 KB (1,241 words) - 12:55, 30 May 2025
5-HT2C receptor antagonist Zolmitriptan (ML-004) – serotonin 5-HT1B and 5-HT1D receptor agonist Batoprazine – serotonin 5-HT1A and 5-HT1B receptor agonist...
29 KB (2,976 words) - 21:43, 9 June 2025
receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...
59 KB (6,182 words) - 23:06, 22 May 2025
including 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F. Receptors of the 5-HT1 type, specifically, the 5-HT1A and 5-HT1D receptor subtypes, are present...
5 KB (472 words) - 15:42, 23 May 2025
depression. P11 interacts with the serotonin receptor proteins, 5-HT receptors such as 5-HT1B, a receptor involved in the physiological effect of locomotor...
39 KB (4,728 words) - 16:31, 22 December 2024
SB-224289 (category 5-HT1B antagonists)
serotonin 5-HT1B receptor antagonist or inverse agonist which is used in scientific research. It is more than 75-fold selective for the serotonin 5-HT1B receptor...
5 KB (338 words) - 06:12, 2 March 2025
Serotonin (redirect from 5-Hydroxytryptamine)
different receptors. Through 5-HT1B receptors, it negatively regulates bone mass, while it does so positively through 5-HT2B receptors and 5-HT2C receptors. There...
173 KB (18,295 words) - 19:45, 2 June 2025
5-HT1D receptor agonists are pharmaceutical drugs for the treatment of migraine. They include: Triptans (which additionally act as 5-HT1B receptor agonists)...
413 bytes (78 words) - 00:39, 25 June 2024
BRL-15572 (category 5-HT1D antagonists)
similar pharmacology to the closely related 5-HT1B receptor, and most older ligands for these receptors bind to both subtypes with approximately equal...
4 KB (338 words) - 08:01, 16 April 2025
RU-24969 (category 5-HT1B agonists)
serotonin 5-HT1A and 5-HT1B receptors, with 5-fold preference for the latter receptor over the former. It also has affinity for the serotonin 5-HT5A, 5-HT5B...
6 KB (509 words) - 04:23, 28 April 2025
ASR-2001 (redirect from 5-PrO-2C-B)
serotonin 5-HT2B receptor (94-fold in terms of activational potency). It is also a highly potent agonist of the serotonin 5-HT1B receptor, whereas its...
10 KB (808 words) - 00:44, 7 June 2025
CP-93129 (category Serotonin receptor agonists)
selective serotonin 5-HT1B receptor agonist, with approximately 150x and 200x selectivity over the closely related 5-HT1D and 5-HT1A receptors. It is used in...
3 KB (302 words) - 07:30, 12 January 2024
ASR-3001 (redirect from 5-methoxy-N-allyl-N-isopropyltryptamine)
serotonin 5-HT2A receptor, 46.8 nM at the serotonin 5-HT1B receptor, 87.4 nM at the serotonin 5-HT2B receptor, 420 nM at the serotonin 5-HT6 receptor, and...
9 KB (730 words) - 04:21, 19 May 2025
TACT908 (category 5-HT1B agonists)
as a serotonin 5-HT1B and 5-HT2A receptor agonist. Its EC50Tooltip half-maximal effective concentration at the serotonin 5-HT2A receptor is 52 nM (EmaxTooltip...
7 KB (368 words) - 02:50, 17 March 2025
Locomotor activity (section Dopamine receptor agonists)
serotonin 5-HT1B and 5-HT2A receptor antagonism. Conversely, the serotonin 5-HT1A receptor is not involved in MDMA-induced hyperlocomotion. Serotonin 5-HT2C...
114 KB (12,382 words) - 04:41, 2 June 2025
serotonin receptors, and is unusual in that it acts as an antagonist at the 5-HT1B receptor, but is an agonist at the closely related 5-HT1D receptor. Morton...
3 KB (107 words) - 05:08, 12 April 2025
Sumatriptan (category 5-HT1B agonists)
generally occur within three hours. Its primary effect as a serotonin 5-HT1B/5-HT1D receptor agonist can create common side effects such as chest pressure, fatigue...
32 KB (2,879 words) - 02:30, 10 June 2025
GR-55562 (category 5-HT1B antagonists)
GR-55562 is a selective serotonin 5-HT1B and 5-HT1D receptor antagonist. It is one of several selective serotonin 5-HT1B receptor antagonists used in scientific...
6 KB (439 words) - 10:44, 31 October 2024
SB-216641 (category 5-HT1B antagonists)
selective antagonist for the serotonin receptor 5-HT1B, with around 25x selectivity over the closely related 5-HT1D receptor. It is used in scientific research...
4 KB (320 words) - 08:02, 27 October 2024
The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)...
131 KB (13,680 words) - 11:36, 9 June 2025
serotonin reuptake inhibitor, serotonin 5-HT1A and 5-HT1B receptor agonist, and serotonin 5-HT1D, 5-HT3, and 5-HT7 receptor antagonist Zimelidine (Zelmid) –...
151 KB (11,543 words) - 23:22, 9 June 2025
Triptan (category 5-HT1D agonists)
pain. The drugs of this class act as agonists for serotonin 5-HT1B and 5-HT1D receptors at blood vessels and nerve endings in the brain. The first clinically...
39 KB (3,795 words) - 10:13, 4 June 2025
RU-28253 (category 5-HT1B agonists)
the serotonin 5-HT1 and 5-HT2 receptors, including of the serotonin 5-HT1B receptor, and is also an agonist of the serotonin 5-HT4 receptor. RU-28253 was...
6 KB (467 words) - 04:33, 3 April 2025
serotonin 5-HT1B receptor, 7,100 nM for the serotonin 5-HT1A receptor, and >10,000 nM for the serotonin 5-HT1D receptor, whereas other serotonin receptors were...
6 KB (561 words) - 17:24, 27 March 2025
5-(Nonyloxy)tryptamine (5-NOT) is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length...
3 KB (178 words) - 17:23, 27 March 2025