• done mainly through its expression in the hippocampus and the amygdala. Studies supporting the role of CREB in cognition include those that knock out the...
    14 KB (1,748 words) - 07:34, 4 April 2025
  • Thumbnail for CREB
    melanogaster, in rats and in mice (see CREB in Molecular and Cellular Cognition). CREB is necessary for the late stage of long-term potentiation. CREB also has...
    19 KB (2,243 words) - 23:46, 9 September 2024
  • Molecular cellular cognition (MCC) is a branch of neuroscience that involves the study of cognitive processes with approaches that integrate molecular...
    4 KB (517 words) - 21:32, 24 October 2023
  • Thumbnail for KMT2A
    HJ, Wright PE (November 2002). "Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia...
    20 KB (2,275 words) - 19:46, 29 June 2024
  • experiences and the environment to produce individual differences in behaviour, cognition, personality, and mental health. Epigenetic gene regulation involves...
    61 KB (7,936 words) - 18:24, 19 April 2025
  • Thumbnail for PI3K/AKT/mTOR pathway
    localizing it in the plasma membrane. AKT can have a number of downstream effects such as activating CREB, inhibiting p27, localizing FOXO in the cytoplasm...
    36 KB (4,322 words) - 19:17, 30 March 2025
  • which in turn activates various signal pathways that ultimately activate the ERK pathway which then modulates transcription factors like CREB. CREB then...
    52 KB (6,235 words) - 08:34, 10 May 2025
  • cAMP response element-binding protein (CREB). Phosphorylated CREB, together with its coactivators, p300 and CREB-binding protein (CBP) enhances the transcription...
    12 KB (1,281 words) - 15:01, 22 July 2024
  • Thumbnail for Tianeptine
    is upregulated by CREB, it could be hypothesized that due to tianeptine's central role in BDNF and neuronal plasticity, this CREB may be the transcription...
    71 KB (6,456 words) - 20:45, 12 May 2025
  • Thumbnail for Reward system
    beneficial stimuli and minimizing contact with harmful stimuli. Reward cognition serves to increase the likelihood of survival and reproduction by causing...
    106 KB (13,103 words) - 04:04, 24 February 2025
  • Thumbnail for Metadoxine
    and fat accumulation in alcoholic fatty liver. Metadoxine may block the differentiation step of preadipocytes by inhibiting CREB phosphorylation and binding...
    18 KB (1,907 words) - 03:58, 25 November 2024
  • Thumbnail for Pharmacology of ethanol
    protein (CREB), inducing CREB-mediated changes in gene expression. With chronic alcohol intake, consumption of ethanol similarly induces CREB phosphorylation...
    98 KB (10,607 words) - 10:24, 29 April 2025
  • Thumbnail for Adderall
    levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating CREB, also...
    63 KB (22,705 words) - 23:57, 9 May 2025
  • Motivational salience (category Cognition)
    Sage JR, Shuman T, Anagnostaras SG (January 2014). "Psychostimulants and cognition: a continuum of behavioral and cognitive activation". Pharmacol. Rev....
    23 KB (3,234 words) - 08:22, 7 February 2024
  • transduction pathway are necessary for conditioning related plasticity. CREB is also necessary for conditioning related plasticity, and it may induce...
    66 KB (8,779 words) - 22:17, 23 April 2025
  • Earth's Children (category Official website different in Wikidata and Wikipedia)
    role in the conception, although it may be called on to help subdue a woman's unusually strong totem. In "Clan of the Cave Bear", two people, Creb and...
    26 KB (3,870 words) - 02:40, 22 February 2025
  • Thumbnail for Alcino J. Silva
    in 2013 for his contributions to the molecular cellular cognition of memory, a field he pioneered with the publication of two articles in Science in 1992...
    58 KB (6,318 words) - 22:06, 12 October 2023
  • Thumbnail for Memory
    The cAMP response element-binding protein (CREB) is a transcription factor which is believed to be important in consolidating short-term to long-term memories...
    138 KB (16,929 words) - 21:22, 10 May 2025
  • Thumbnail for Alpha-7 nicotinic receptor
    subtype-selective Tilorone. A-582941: partial agonist; activates ERK1/2 and CREB phosphorylation; enhances cognitive performance AR-R17779: full agonist,...
    28 KB (2,815 words) - 14:12, 9 May 2025
  • Thumbnail for Methamphetamine
    Methamphetamine (category All Wikipedia articles written in American English)
    protein (CREB), and nuclear factor kappa B (NFκB). ΔFosB plays a crucial role in the development of drug addictions, since its overexpression in D1-type...
    170 KB (16,628 words) - 05:02, 11 May 2025
  • Thumbnail for Priya Rajasethupathy
    Neural Dynamics and Cognition. Priya Rajasethupathy grew up in Brockport, New York. She received her Bachelor of Arts degree in biology with a pre-medicine...
    10 KB (980 words) - 19:28, 3 September 2024
  • Thumbnail for Addiction
    Addiction (category All Wikipedia articles written in American English)
    reward-sensitizing effect, CREB transcriptional activity decreases user's sensitivity to the rewarding effects of the substance. CREB transcription in the nucleus accumbens...
    204 KB (23,488 words) - 17:14, 12 May 2025
  • Thumbnail for Dextroamphetamine
    levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating CREB, also...
    64 KB (21,777 words) - 04:41, 11 May 2025
  • The cAMP response element-binding protein (CREB) is a transcription factor which is believed to be important in consolidating short- to long-term memories...
    55 KB (7,012 words) - 05:40, 3 May 2025
  • miRNA signature of human plasma. One pathway that involves miRNA is the CREB (cAMP responsive element binding protein) and BDNF (brain-derived neurotrophic...
    73 KB (8,901 words) - 12:36, 16 August 2024
  • Thumbnail for Serotonin
    wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, memory...
    169 KB (17,900 words) - 00:02, 10 May 2025
  • Thumbnail for Amphetamine
    Amphetamine (category Products introduced in 1887)
    levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating CREB, also...
    306 KB (32,344 words) - 13:24, 14 May 2025
  • Thumbnail for Ventral tegmental area
    implicated in the drug and natural reward circuitry of the brain. The VTA plays an important role in a number of processes, including reward cognition (motivational...
    41 KB (4,970 words) - 17:58, 28 January 2025
  • cognition, the transcription factor cAMP response element-binding protein (CREB) Convergence and divergence between the transcriptional responses to Zika...
    27 KB (3,527 words) - 20:37, 12 May 2024
  • Cassava Sciences (category 1998 establishments in California)
    Pentapeptide Binding Site on Filamin A Blocks Mu Opioid Receptor–Gs Coupling and CREB Activation of Acute Morphine". PLOS ONE. 17 (3): e0266629. Bibcode:2022PLoSO...
    53 KB (5,506 words) - 18:01, 3 May 2025