Cardiac contractility modulation is a therapy which is intended for the treatment of patients with moderate to severe heart failure (NYHA class II–IV)...

(CRT) or cardiac contractility modulation may be beneficial. In severe disease that persists despite all other measures, a cardiac assist device ventricular...

concentrating mechanisms, a photosynthesis condition in plants Cardiac contractility modulation, a therapy for heart failure Cerebral cavernous malformation...

2016). "Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility". Archives...

that regulates cardiac function independently of the central nervous system. It modulates heart rate, conduction, and cardiac contractility in response to...

duration of 120 ms or less), CRT may actually be harmful. CCM: Cardiac Contractility Modulation (CCM) is a treatment for patients with moderate to severe left...

interrupting the cardiac excitation-contraction coupling process to cause a reduction in contractility. During cardiogenesis, migration of the cardiac neural crest...

(end-diastolic index) by use of ultrasound. Contractility is not routinely assessed; quite often inotropy and contractility are interchanged as equal terms. Afterload...

changes in action potentials due to ion channel blockers and modulation of contractile properties by inotropic and lusitropic agents. Even with current...

Schaub MC, Hefti MA, Zuellig RA, Morano I (Feb 1998). "Modulation of contractility in human cardiac hypertrophy by myosin essential light chain isoforms"...

Cardiac excitation-contraction coupling (Cardiac EC coupling) describes the series of events, from the production of an electrical impulse (action potential)...

and through modulation of muscarinic potassium channels. Additionally, M2 receptors reduce the contractile forces of the atrial cardiac muscle and reduce...

2016). "Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility". Archives...

compared to cardiac muscle. Increased cAMP will promote relaxation in smooth muscle, while promoting increased contractility and pulse rate in cardiac muscle...

calcium and increases the contractility of their respective cardiac myocytes. L-type calcium channel blocker drugs are used as cardiac antiarrhythmics or antihypertensives...

(Serine43/45Alanine) exhibited enhanced cardiac contractility. In addition to sarcomeres, PKCε also targets cardiac mitochondria. Proteomic analysis of PKCε...

Amelia; Ward, Marie-Louise (14 January 2020). "Stretch modulation of cardiac contractility: importance of myocyte calcium during the slow force response"...

quantium Medical Cardiac Output (qCO) uses impedance cardiography in a simple, continuous, and non-invasive way to estimate the cardiac output (CO) and...

nervous system: slowing down the heart rate, reducing contractile forces of the atrial cardiac muscle, and reducing conduction velocity of the sinoatrial...

; Solaro, R. John; Layland, Joanne (2005-04-01). "Regulation of cardiac contractile function by troponin I phosphorylation". Cardiovascular Research...

and Function of N-terminal Variable Region of Troponin T: Modulation of Muscle Contractility and Beyond", International Review of Cell and Molecular Biology...

by stroke volume. It is directly related to heart rate, myocardial contractility, and preload, and inversely related with afterload. Elevated vascular...

playing a role in heart contractility. In contrast to smooth and skeletal muscle MLCKs, cMLCK expression is restricted to cardiac myocytes. Overexpression...

greater alveolar oxygen exchange Increases heart rate and the contractility of cardiac cells (myocytes), thereby providing a mechanism for enhanced blood...

Fitzgerald P and Kass DA. Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans. Circulation. 2005;112:2642-2649 Takimoto E, Champion...

inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac contractility, central osmocontrol and extracellular...

vasodilation, decreases heart rate and blood pressure, and improves myocardial contractility, which ultimately decreases the heart's workload. Carvedilol reduces...

increase in sympathetic activity leading to increased heart rate and contractility. Ionic calcium is antagonized by magnesium ions in the nervous system...

interaction between TSPO and calcium channels can alter cardiac action potential durations, thus contractility of the heart. In healthy individuals, TSPO has a...

is characterized by impaired ventricular emptying, caused by reduced contractility. Diastolic dysfunction is defined by defective ventricular filling,...