Chiral analysis refers to the quantification of component enantiomers of racemic drug substances or pharmaceutical compounds. Other synonyms commonly...

reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric...

chemists as chiral or handed molecules. Each twin is called an enantiomer. Drugs that exhibit handedness are referred to as chiral drugs. Chiral drugs that...

In chemistry, a molecule or ion is called chiral (/ˈkaɪrəl/) if it cannot be superposed on its mirror image by any combination of rotations, translations...

Chirality (/kaɪˈrælɪti/) is a property of asymmetry important in several branches of science. The word chirality is derived from the Greek χείρ (kheir)...

In theoretical physics, a chiral anomaly is the anomalous nonconservation of a chiral current. In everyday terms, it is analogous to a sealed box that...

A chiral switch is a chiral drug that has already approved as racemate but has been re-developed as a single enantiomer. The term chiral switching was...

diastereomers can allow analysis. The use of chiral derivatizing agents has declined with the popularization of chiral HPLC. Besides analysis, chiral derivatization...

specifying one of the two enantiomers (the absolute configuration) of a given chiral molecule: the R/S system is based on the geometry of the molecule; the (+)-...

Chiral column chromatography is a variant of column chromatography that is employed for the separation of chiral compounds, i.e. enantiomers, in mixtures...

Chirality timeline presents a timeline of landmark events that unfold the developments happened in the field of chirality. Many molecules come in two...

Chiral inversion is the process of conversion of one enantiomer of a chiral molecule to its mirror-image version with no other change in the molecule...

science, environment analysis, and hospitals. Affinity chromatography Aqueous normal-phase chromatography Binding selectivity Chiral analysis Chromatofocusing...

scattering and optical activity effects to reveal detailed information on chiral centers in molecules. Raman spectroscopy Saturated spectroscopy Scanning...

"Synthesis of TRIP and Analysis of Phosphate Salt Impurities". Synlett. 2010 (14): 2189–2192. doi:10.1055/s-0030-1258505. ISSN 0936-5214. "Chiral Phosphoric Acids"...

that has equal amounts (50:50) of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds...

(T), the methyl substituent becomes chiral. Methods exist to produce optically pure methyl compounds, e.g., chiral acetic acid (deuterotritoacetic acid...

chromatography with columns having a chiral stationary phase allows analyzing mixtures of enantiomers. The analysis of the enantiomeric distribution of...

cases are not chiral. Generally a chiral and/or bianisotropic electromagnetic response is a consequence of 3D geometrical chirality: 3D-chiral metamaterials...

Homochirality is a uniformity of chirality, or handedness. Objects are chiral when they cannot be superposed on their mirror images. For example, the left...

QCD has spontaneous chiral symmetry breaking with the formation of a chiral condensate. Other phases of QCD may break the chiral flavour symmetries in...

contrast, is not chiral; the mirror image of its molecule is also obtained by a half-turn about a suitable axis. Another example of a chiral compound is 2...

Through the Looking Glass: Uses of NMR Spectroscopy in the Analysis and Synthesis of Chiral Pharmaceuticals." 1994. [2] Ultraviolet-visible spectroscopy...

physiologic conditions, if the hydrogen on the chiral carbon were removed and then replaced with opposite chirality. An experiment in rats given each enantiomer...

desired chirality thus simplifying the target. Directing a synthesis toward a desirable intermediate can greatly narrow the focus of analysis. This allows...

enophile. In terms of the diastereoselection with respect to the newly created chiral centers, an endo preference has been qualitatively observed, but steric...

in the areas of natural products chemistry, protein chemistry, and chiral analysis by liquid chromatography. Bhushan began his education in his native...

followed by chiral chromatographic separation of the enantiomers. An early enantioselective route to atorvastatin made use of an ester chiral auxiliary...

asymmetric packing, which results in longer-range chiral order. In the smectic C* phase (an asterisk denotes a chiral phase), the molecules have positional ordering...

Fulton & Harris (1991). Jurgen Jost, "Riemannian Geometry and Geometric Analysis" (2002) Springer-Verlag Universitext ISBN 3-540-42627-2. See chapter 1...