first antiandrogen was discovered in the 1960s. Antiandrogens antagonise the androgen receptor (AR) and thereby block the biological effects of testosterone...

development of antiandrogens Discovery and development of cephalosporins Retrometabolic drug design "The drug development process". US Food and Drug Administration...

conditions in men and women. They are the converse of steroidal antiandrogens (SAAs), which are antiandrogens that are steroids and are structurally related...

effects of antiandrogens depend on the type of antiandrogen and the specific antiandrogen in question. In any case, common side effects of antiandrogens in...

purpose. They are the converse of nonsteroidal antiandrogens (NSAAs), which are antiandrogens that are not steroids and are structurally unrelated to testosterone...

from the addition of an antiandrogen, as antiandrogens can reduce or eliminate such symptoms. Steroidal antiandrogens are antiandrogens that resemble steroid...

pharmaceutical drug for the treatment of benign prostatic hyperplasia. Discovery and development of antiandrogens List of 5α-reductase inhibitors Aggarwal...

"[Hormonal antiandrogens in acne treatment]" [Hormonal antiandrogens in acne treatment]. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the...

enobosarm) Steroidal antiandrogens (e.g., cyproterone acetate, chlormadinone acetate, spironolactone, oxendolone) Nonsteroidal antiandrogens (e.g., flutamide...

Comparison of the nonsteroidal antiandrogen (NSAA) bicalutamide with other antiandrogens reveals differences between the medications in terms of efficacy...

to antigonadotropic antiandrogens. As an example, because NSAAs do not reduce estrogen levels, unlike antigonadotropic antiandrogens, they preserve bone...

of antiandrogens List of antibiotics List of antipsychotics List of antiviral drugs List of corticosteroid esters List of corticosteroids List of designer...

the treatment of hidradenitis suppurativa in girls and women. Finasteride and other antiandrogens might be useful in the treatment of obsessive–compulsive...

PMID 19432422. [C]linically relevant antiandrogens currently are nonsteroidal anilide derivatives. Antiandrogens used for prostate cancer include the...

from the development of synthetic PR-modulator drug candidates. Ever since the discovery of the progesterone hormone in the mid-1930s. and especially...

treatment of androgen-dependent skin and hair conditions, and hence can significantly augment the effectiveness of antiandrogens in the treatment of such conditions...

medicines. Drug discovery and drug development are complex and expensive endeavors undertaken by pharmaceutical companies, academic scientists, and governments...

and/or inhibiting or suppressing estrogen production. Antiestrogens are one of three types of sex hormone antagonists, the others being antiandrogens...

(2001). "Clinical Use and Abuse of Androgens and Antiandrogens". In Becker KL (ed.). Principles and Practice of Endocrinology and Metabolism. Lippincott...

pure antiandrogen to be developed, with other closely following examples of this class including the steroidal antiandrogens benorterone and BOMT and the...

receptor prevent the side effects associated with the antiandrogens traditionally used for treatment of BPH. Andarine was first described in the literature...

breast development in males due to its estrogenic effects. Unlike other kinds of antiandrogens, it may have less adverse effect on the testes and fertility...

similarly to nonsteroidal antiandrogens like bicalutamide and enzalutamide, EM-5854 is a pure or silent antagonist of the AR and shows no intrinsic partial...

to the discovery of 4-hydroxyandrostenedione (4-OH-A), a potent selective aromatase inhibitor. After the Brodies demonstrated the reduction of estrogen...

pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: relation of their systemic activity to the formation of a common metabolite"...

mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509". Cancer Discovery. 3 (9): 1020–9. doi:10.1158/2159-8290.CD-13-0226...

"Steroidal Antiandrogens". In Jordan VC, Furr BJ (eds.). Hormone Therapy in Breast and Prostate Cancer. Cancer Drug Discovery and Development. Humana Press...

unlike nonsteroidal antiandrogens. As such, it is thought that the partial androgenic activity of CPA and other steroidal antiandrogens underlies the superior...

like all antiandrogens, it can interfere with the androgen-mediated sexual differentiation of the genitalia (and brain) during prenatal development. In pregnant...

Liu B, Su L, Geng J, Liu J, Zhao G (October 2010). "Developments in nonsteroidal antiandrogens targeting the androgen receptor". ChemMedChem. 5 (10):...