• Thumbnail for MMP2
    (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene. The MMP2 gene is located on chromosome 16 at position 12.2. Proteins of the...
    24 KB (2,820 words) - 11:29, 19 July 2025
  • Thumbnail for Intracranial aneurysm
    interleukin 1 beta, interleukin 6, tumor necrosis factor alpha (TNF alpha), MMP1, MMP2, MMP9, prostaglandin E2, complement system, reactive oxygen species (ROS)...
    41 KB (4,545 words) - 00:34, 18 July 2025
  • Thumbnail for Bicuspid aortic valve
    reduced Fibrillin-1. It is currently believed that an increase in the ratio of MMP2 (Matrix Metalloproteinases 2) to TIMP1 (tissue inhibitors of metalloproteinase)...
    21 KB (2,392 words) - 17:33, 3 October 2024
  • Thumbnail for Cort Guitars
    with 'tree of life' inlay up the neck and finished in antique sunburst, an MMP2 and MMP3 available in "transparent cannon blue" and "brown burst" finishes...
    12 KB (1,191 words) - 23:46, 21 April 2025
  • Thumbnail for Disc herniation
    interleukin-1, and interleukin-6 polymorphisms. Mutation in genes – such as MMP2 and THBS2 – that encode for proteins and enzymes involved in the regulation...
    55 KB (6,595 words) - 23:16, 17 July 2025
  • Thumbnail for Winchester syndrome
    mutations in the matrix metalloproteinase 2 (MMP2) gene. A 2006 study showed other mutations found in the MMP2 gene. This has led to the belief that there...
    12 KB (1,295 words) - 18:59, 16 July 2025
  • Thumbnail for Degenerative disc disease
    interleukin-1, and interleukin-6 polymorphisms. Mutation in genes – such as MMP2 and THBS2 – that encode for proteins and enzymes involved in the regulation...
    27 KB (3,210 words) - 20:08, 17 July 2025
  • CLGN secreted Substrates include Col I, II, III, VII, VIII, X, gelatin MMP2 Gelatinase-A, 72 kDa gelatinase secreted Substrates include Gelatin, Col...
    23 KB (2,313 words) - 16:27, 4 May 2025
  • Thumbnail for Astrocyte
    (PGE2). Activated astrocytes are also a source of matrix metalloproteinase 2 (MMP2), which induces pro-IL-1β cleavage and sustains astrocyte activation. In...
    84 KB (9,444 words) - 20:03, 11 July 2025
  • Thumbnail for Alamandine
    decreased pro-inflammatory (IL-1β, TNF alpha and CCL2) and pro-fibrotic factors (MMP2 and TGF β1), and increased pro-resolution markers (MRC1 and FIZZ1) Almandine...
    10 KB (810 words) - 15:26, 17 July 2025
  • Chang K, Oi Y, Milewicz DM (*Authors contribution equal). Association of MMP2 and MMP9 polymorphisms with intracranial aneurysms. J Neurosurg. 105(3):418-23...
    7 KB (851 words) - 04:46, 5 August 2023
  • Thumbnail for MicroRNA
    with increase in p53 effector genes including Bax, Trp53inp1, Jun, Cdkn1a, Mmp2, and Arid3a. p53 protein levels remained unchanged, suggesting that FoxD1...
    147 KB (16,651 words) - 18:23, 28 July 2025
  • Thumbnail for Hsp90
    the invasion step of metastasis by assisting the matrix metalloproteinase MMP2. Together with its co-chaperones, Hsp90 modulates tumour cell apoptosis "mediated...
    51 KB (5,551 words) - 00:49, 20 June 2025
  • Thumbnail for Basigin
    (August 2002). "Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway"...
    22 KB (2,517 words) - 21:25, 15 July 2025
  • gelatinases expressed are matrix metalloproteinases MMP2 and MMP9. Additionally, gelatinases A (MMP2) and B (MMP9) have been proven to assist in developing...
    11 KB (1,258 words) - 04:07, 12 July 2025
  • Thumbnail for CCL7
    after 3–5 days after the stimulation. CCL7 has been shown to interact with MMP2 by binding CCR2 receptor. CCL7 is a multipotent chemokine involved in anti-bacterial...
    21 KB (2,539 words) - 11:56, 29 July 2024
  • Thumbnail for MMP14
    matrix remodeling, cell migration, and activation of other MMPs, notably pro-MMP2. MMP14 (matrix metalloproteinase-14) is a membrane-anchored enzyme with critical...
    9 KB (1,064 words) - 11:37, 5 July 2025
  • Thumbnail for MMP24
    expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been...
    5 KB (620 words) - 17:27, 17 July 2025
  • Thumbnail for Fibrillin-1
    vulnerable to be activated in a protease-dependent or independent manner. MMP2 and MMP9 are select TGF-β activators and ligands and are found in higher...
    29 KB (3,496 words) - 16:35, 17 July 2025
  • HGNC:14668 Q495T6 9654 MMGT1 HGNC:28100 Q8N4V1 9655 MMP1 HGNC:7155 P03956 9656 MMP2 HGNC:7166 P08253 9657 MMP3 HGNC:7173 P08254 9658 MMP7 HGNC:7174 P09237 9659...
    277 KB (17 words) - 09:51, 23 June 2025
  • Thumbnail for Notch signaling pathway
    Notch may regulate this process by activating matrix metalloproteinase2 (MMP2) expression, or by inhibiting vascular endothelial (VE)-cadherin expression...
    95 KB (11,033 words) - 11:58, 18 July 2025
  • Thumbnail for MMP16
    protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. GRCh38:...
    8 KB (982 words) - 17:58, 16 July 2025
  • Thumbnail for UCK2
    It appears to activate oncogenic pathways, such as STAT3 and enzymes like MMP2 and MMP9, which contribute to enhanced cell proliferation and metastasis...
    23 KB (2,778 words) - 07:39, 19 July 2025
  • Thumbnail for Lymphangioleiomyomatosis
    Kwiatkowski DJ (February 2010). "Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like...
    100 KB (11,094 words) - 07:33, 12 July 2025
  • Thumbnail for TPX2
    hepatocellular carcinoma cell invasion via inactivating AKT signaling and inhibiting MMP2 and MMP9 expression". Chinese Journal of Cancer Research. 26 (4): 410–7....
    38 KB (4,947 words) - 04:52, 15 July 2025
  • Thumbnail for Fibronectin type II domain
    attach to the cell membrane. BSPH1; ELSPBP1; F12; FN1; HGFAC; IGF2R; LY75; MMP2; MMP9; MRC1; MRC1L1; MRC2; PLA2R1; SEL1L; Fibronectin type I domain: F12;...
    7 KB (808 words) - 13:40, 22 March 2023
  • agenesis, selective, X-linked 1; 313500; ED1 Torg–Winchester syndrome; 259600; MMP2 Tourette syndrome; 137580; SLITRK1 Townes–Brocks branchiootorenal-like syndrome;...
    234 KB (18,877 words) - 18:07, 24 March 2025
  • Thumbnail for ATF3
    v t e Regulome Inhibits MMP2, adiponectin Is activated by not...
    14 KB (1,701 words) - 05:10, 19 July 2025
  • Thumbnail for LRP1
    Lactoferrin, Lipoprotein lipase, LPL, MAPK8IP1, MAPK8IP2, Midkine, MMP13, MMP2, MMP9, Neuroserpin, Nexin-1, NOS1AP, PAI 2, PAI-1, PDGF, tPA, uPA, Polymyxin...
    32 KB (3,451 words) - 07:50, 15 July 2025
  • Thumbnail for MMP7
    MMP7 activity. The activated MMP7 can also cleave the propeptides of proMMP2 and proMMP9 to facilitate tumor invasion. Quondamatteo et al. immunohistochemically...
    17 KB (2,274 words) - 17:28, 17 July 2025