Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and...
16 KB (1,930 words) - 01:51, 11 December 2023
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 15:04, 24 May 2025
The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. It is encoded in the human by the...
9 KB (1,097 words) - 22:30, 27 March 2024
Coagulation (redirect from Platelet activation)
vessel wall). Activation of platelets and platelet plug formation: Platelet activation: Platelet activators, such as platelet activating factor and thromboxane...
64 KB (6,646 words) - 08:40, 9 June 2025
Rupatadine is a second generation antihistamine and platelet-activating factor antagonist used to treat allergies. It was discovered and developed by Uriach [es]...
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Jacques Benveniste (section Platelet-activating factor)
born in Paris. In 1979, he published a paper on the structure of platelet-activating factor and its relationship with histamine. He was head of allergy and...
30 KB (3,160 words) - 18:56, 22 May 2025
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This...
14 KB (1,641 words) - 23:08, 5 September 2024
and muscle relaxant effects, and also acts as an inhibitor of platelet-activating factor (PAF). Brotizolam Etizolam Flubrotizolam Fluclotizolam Deschloroclotizolam...
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(along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they...
71 KB (8,529 words) - 20:44, 19 June 2025
Platelet-activating factor acetylhydrolase IB subunit alpha or Lisencephaly protein-1 (LIS-1) is an enzyme that in humans is encoded by the PAFAH1B1 gene...
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Ether lipids can also act directly in cell signaling, as the platelet-activating factor is an ether lipid signaling molecule that is involved in leukocyte...
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Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme that in...
12 KB (1,378 words) - 21:36, 20 September 2024
In enzymology, a platelet-activating factor acetyltransferase (EC 2.3.1.149) is an enzyme that catalyzes the chemical reaction 1-alkyl-2-acetyl-sn-gly...
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developed to treat severe sepsis. Pafase is the recombinant form of platelet-activating factor acetylhydrolase (PAF-AH, also known as lipoprotein-associated...
44 KB (4,452 words) - 21:08, 29 May 2025
a potent and selective inhibitor of the phospholipid mediator platelet-activating factor (PAF). It was developed by structural modification of the...
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and hydrogels, and for positron emission tomography. Hexadecyl platelet-activating factor has profound effects on the lung, and hexadecyl glyceryl ether...
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danger activating thrifty genes in order to store fat and to avoid starvation. BAFF shares many activities with PAF (Platelet Activating Factor) and they...
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extension of PortableApps files Paroxysmal atrial fibrillation Platelet-activating factor Population attributable fraction (epidemiology) Pure autonomic...
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(Y-24180) is a drug which acts as a selective antagonist for the platelet-activating factor receptor, and was originally developed for the treatment of asthma...
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identity generated a list of candidates including carbon monoxide, platelet-activating factor, arachidonic acid, and nitric oxide. Nitric oxide has received...
26 KB (3,056 words) - 21:11, 23 May 2025
primarily by activation of ceramidase by growth-inducing proteins such as platelet-derived growth factor and insulin-like growth factor, is consistent...
55 KB (5,633 words) - 08:40, 12 July 2024
class of molecules has been studied for its potential to act as a platelet-activating factor receptor antagonist. Ginkgolide B has been investigated for its...
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substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both...
5 KB (583 words) - 19:49, 8 April 2022
tissue trauma. Mast cell granules contain histamine, heparin, platelet-activating factor, and other substances. Disseminated mastocytosis is rarely seen...
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1-alkyl-2-acetylglycerophosphocholine esterase (redirect from Platelet-activating factor acetylhydrolase)
as platelet-activating factor. There are multiple enzymes with this function: Lipoprotein-associated phospholipase A2 Platelet-activating factor acetylhydrolase...
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hazing after surgery is also decreased with brush technique. The platelet activating factor blocker LAU-0901 has shown effect in mitigating dry eye in mouse...
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causing degranulation. Granules in these cells contain histamine, platelet-activating factor, and other compounds causing clinical manifestation of anaphylaxis-...
44 KB (4,096 words) - 22:53, 25 October 2024
This will change platelet's shape and induce release of serotonin, ADP, vWF (Von Willebrand factor), PAF (Platelet-activating factor) to promote further...
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Fc receptor (section Activation)
proteases. Activated mast cells also synthesize and secrete lipid-derived mediators (such as prostaglandins, leukotrienes, and platelet-activating factor) and...
42 KB (4,735 words) - 10:51, 22 May 2025
transmission by platelet-activating factor. Neuron 9:1211-1216, 1992 Kato K, Clark GD, Bazan NG, Zorumski CF: Platelet activating factor as a potential...
31 KB (4,361 words) - 03:11, 26 January 2025