Protein primary structure is the linear sequence of amino acids in a peptide or protein. By convention, the primary structure of a protein is reported...

Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers – specifically polypeptides – formed...

Protein tertiary structure is the three-dimensional shape of a protein. The tertiary structure will have a single polypeptide chain "backbone" with one...

tertiary structure from primary structure. Structure prediction is different from the inverse problem of protein design. Protein structure prediction...

Protein secondary structure is the local spatial conformation of the polypeptide backbone excluding the side chains. The two most common secondary structural...

three-dimensional structure, known as the protein's native state. This structure is determined by the amino-acid sequence or primary structure. The correct...

were amino acids linked by peptide bonds, although this model of protein primary structure was independently and simultaneously conceived by Emil Fischer...

Protein quaternary structure is the fourth (and highest) classification level of protein structure. Protein quaternary structure refers to the structure...

entire protein subunits. This useful distinction among scales is often expressed as a decomposition of molecular structure into four levels: primary, secondary...

alteration of the native secondary, and/or tertiary, and/or quaternary structures of proteins or nucleic acids resulting in a loss of bioactivity. Note 1: Modified...

specific structure which enables the protein to carry out its functions. The basic form of protein structure is known as the primary structure, which is...

a protein structure database is a database that is modeled around the various experimentally determined protein structures. The aim of most protein structure...

novo protein structure prediction refers to an algorithmic process by which protein tertiary structure is predicted from its amino acid primary sequence...

users. Even though the primary goal of CASP is to help advance the methods of identifying protein three-dimensional structure from its amino acid sequence...

responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily...

because protein folding requires entropic cost. As a primary sequence of a polypeptide chain can form numerous conformations, native globular structure restricts...

biology, an intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure, typically in the absence of its...

Quinary structure is thus the fifth level of protein complexity, additional to protein primary, secondary, tertiary and quaternary structures. As opposed...

The particular series of amino acids that form a protein is known as that protein's primary structure. This sequence is determined by the genetic makeup...

using X-ray crystallography, the alternative method of sequencing protein primary structure may also be used instead. Porins are water-filled pores and channels...

prion protein (PrP) is encoded in the human body by the PRNP gene also known as CD230 (cluster of differentiation 230). Expression of the protein is most...

to its primary host receptor, CD4, and its co-receptor (mainly CCR5 or CXCR4), leading to viral entry into its target cell. As the only proteins on the...

nonsense mutation, can alter the primary structure of a protein. In this case, a truncated protein is produced. Protein function and folding is dependent...

A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene and are the result of genetic...

finger protein's class is determined by its three-dimensional structure, but it can also be recognized based on the primary structure of the protein or the...

The Open Protein Structure Annotation Network (TOPSAN) is a wiki designed to collect, share and distribute information about protein three-dimensional...

Rieske proteins are iron–sulfur protein (ISP) components of cytochrome bc1 complexes and cytochrome b6f complexes and are responsible for electron transfer...

along with the G proteins. The signaling pathways activated through a GPCR are limited by the primary sequence and tertiary structure of the GPCR itself...

Antifreeze proteins (AFPs) or ice structuring proteins refer to a class of polypeptides produced by certain animals, plants, fungi and bacteria that permit...

numerous alternative theories of the protein primary structure were proposed, e.g., the colloidal hypothesis that proteins were assemblies of small molecules...