Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses. This is achieved by transforming a target molecule into...
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In retrosynthetic analysis, a synthon is a hypothetical unit within a target molecule that represents a potential starting reagent in the retroactive...
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processes. Key components of natural product synthesis include retrosynthetic analysis, which involves planning synthetic routes by working backward from...
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the theory and methodology of organic synthesis", specifically retrosynthetic analysis. Regarded by many as one of the greatest living chemists, he has...
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groups nearby. Functional group interconversion can be used in retrosynthetic analysis to plan organic synthesis. A functional group is a group of atoms...
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umpolung for reversed polarity) and E.J. Corey. Polarity analysis during retrosynthetic analysis tells a chemist when umpolung tactics are required to synthesize...
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synthesis Petrochemistry Physical organic chemistry Polymer chemistry Retrosynthetic analysis Stereochemistry Alkane stereochemistry Total synthesis / Semisynthesis...
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of the most stable products. Advanced Planning and Techniques: Retrosynthetic analysis is a strategy used to plan complex syntheses by breaking down the...
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chemistry Organic reaction Organic compound Organic synthesis Retrosynthetic analysis Current trends in organic chemistry include (as of 2020): Biocatalysis...
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sinus arrhythmia, the heart rate variation due to respiration Retrosynthetic analysis, in organic chemistry Rsa RNA, partially characterised non-coding...
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often with a minus sign. Retrosynthetic analysis can be applied to design a complex synthesis reaction. Here the analysis starts from the products, for...
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fungicides, herbicides, and pesticides. Some derivatives include: retrosynthetic analysis of vibunazole showed that it was derived from pinacolone. It is...
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enantioselective total synthesis of the correct enantiomer was disclosed. The retrosynthetic analysis was inspired by hyperforin's structural symmetry and biosynthetic...
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F. M. (2012). "Alder-ene reaction: Aromaticity and activation-strain analysis". Journal of Computational Chemistry. 33 (5): 509–516. doi:10.1002/jcc...
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design was coined by Nicholas Bodor. The method is analogous to retrosynthetic analysis where the synthesis of a target molecule is planned backwards....
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Retrosynthetic analysis for the Holton Taxol total synthesis....
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below and was described by the laboratory of K. C. Nicolaou. The retrosynthetic analysis revealed 1, 2, and 3 as the building blocks (Figure 1). As seen...
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19770600329. Zahedi Ehsan; Ali-Asgari Safa; Keley Vahid (2010). "NBO and NICS analysis of the allylic rearrangements (the Cope and 3-aza-Cope rearrangements)...
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Steensma, David P (January 2013). "Elias James Corey—Nobel Prize for Retrosynthetic Analysis". Stamp Vignette on Medical Science. 88 (1): E7. Retrieved 2024-09-19...
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synthesis Petrochemistry Physical organic chemistry Polymer chemistry Retrosynthetic analysis Stereochemistry Alkane stereochemistry Total synthesis / Semisynthesis...
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work has been instrumental in the development of computer-aided retrosynthetic analysis and had significant impact on the development of chemoinformatics...
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C, Zécri FJ, Bulat S (2005). "Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks". J. Am. Chem. Soc. 127...
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B.; Watson, Stephen P.; Hann, Michael M. (1998). "RECAP-Retrosynthetic Combinatorial Analysis Procedure: A Powerful New Technique for Identifying Privileged...
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degradation products.) Chemical modification of PD 138142-15 and retrosynthetic analysis found that avasimibe (then codenamed CI-1011) could be easily manufactured...
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by Hirama et al. Critical to the success of this endeavor was retrosynthetic analysis that focused on the convergent coupling of components with roughly...
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stereoselective synthesis. Many synthetic procedures are developed from a retrosynthetic framework, a type of synthetic design developed by Elias James Corey...
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nature and are not formed during the synthesis from d-lysergic acid. Retrosynthetically, the C-5 stereocenter could be analysed as having the same configuration...
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hydride, is a more favorable process. In broad strokes, and in a formal retrosynthetic sense, titanacyclopropane 1 behaves like a 1,2-dianion which adds into...
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moieties from databases of chemical structures. RECAP (Retrosynthetic Combinatorial Analysis Procedure) uses SMARTS to define bond types. RECAP is a...
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metalation", "linker migration", "domino lattice rearrangement", and "retrosynthetic design". These contributions form the aforementioned "toolkit" for MOF...
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