• Thumbnail for Variant of uncertain significance
    A variant of uncertain (or unknown) significance (VUS) is a genetic variant that has been identified through genetic testing but whose significance to...
    25 KB (2,460 words) - 00:41, 18 October 2024
  • Thumbnail for Beck–Fahrner syndrome
    Beck–Fahrner syndrome (category Disorders of synthesis of DNA, RNA, and proteins)
    and may serve as a tool to confirm the pathogenicity of a TET3 variant of uncertain significance. The management approach for Beck–Fahrner syndrome is...
    21 KB (1,600 words) - 19:13, 1 June 2025
  • Thumbnail for Genome Project–Write
    as of 2004). Among the many goals of GP-Write are the making of cell lines resistant to all viruses and synthesis assembly lines to test variants of unknown...
    7 KB (703 words) - 19:53, 25 May 2025
  • Thumbnail for Kiran Musunuru
    Kiran Musunuru (category Perelman School of Medicine at the University of Pennsylvania faculty)
    Musunuru Kiran (2018-12-11). "Functional Annotation of TNNT2 Variants of Uncertain Significance With Genome-Edited Cardiomyocytes". Circulation. 138...
    15 KB (1,428 words) - 15:28, 25 May 2025
  • VUS or Vus may refer to: Variant of uncertain significance in genetic testing Vus (Crna Trava), village in Serbia Vjesnik u srijedu, Croatian newspaper...
    302 bytes (66 words) - 12:42, 23 October 2017
  • Thumbnail for Variants of SARS-CoV-2
    Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are viruses that, while similar to the original, have genetic changes that are...
    227 KB (21,893 words) - 18:30, 31 May 2025
  • Thumbnail for SARS-CoV-2 Omicron variant
    Omicron (B.1.1.529) is a variant of SARS-CoV-2 first reported to the World Health Organization (WHO) by the Network for Genomics Surveillance in South...
    223 KB (25,432 words) - 22:08, 29 May 2025
  • Thumbnail for McKusick–Kaufman syndrome
    improves diagnostic accuracy and reduces the likelihood of identifying variants of uncertain significance. In cases where other diagnoses are being considered...
    17 KB (1,842 words) - 20:55, 29 May 2025
  • Thumbnail for BRCA mutation
    part of the necessary protein. Suspected deleterious: While nothing is proven, the variation is currently believed to be harmful. Variant of uncertain significance...
    71 KB (8,840 words) - 02:12, 5 June 2025
  • them to study variants of uncertain significance.  Those collaborations have led to gene discovery and have facilitated understanding of rare diseases...
    9 KB (913 words) - 16:52, 25 January 2025
  • Takikawa sea cow (category Pliocene mammals of Asia)
    of by some scientists as a synonym of the Cuesta sea cow (H. cuestae). It is uncertain whether or not the Takikawa sea cow was simply a local variant...
    3 KB (247 words) - 02:54, 6 May 2025
  • Thumbnail for Shapiro–Senapathy algorithm
    "A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer". BMC Medical...
    69 KB (6,804 words) - 04:42, 27 April 2024
  • mathematician Aleksey Krylov around 1908. The main advantage of AIRM over other variants of aggregated indices methods is its ability to cope with poor-quality...
    9 KB (1,132 words) - 21:58, 10 December 2021
  • symbols instead of Ogham letters. Straif is the Irish name of the fourteenth letter of the Ogham alphabet, ᚎ. Old Irish spelling variants are straif, straiph...
    1 KB (209 words) - 16:07, 23 April 2024
  • Thumbnail for Polymorphism (biology)
    use of the words "morph" or "polymorphism" for what is a visibly different geographical race or variant is common, but incorrect. The significance of geographical...
    31 KB (3,947 words) - 02:58, 10 April 2025
  • Thumbnail for OMA1
    disease. 3 heterozygous coding sequence variants of uncertain significance were identified in the OMA1 gene in a screen of 190 individuals with Amyotrophic Lateral...
    13 KB (1,519 words) - 17:01, 23 March 2024
  • Thumbnail for The Flatiron (photograph)
    The Flatiron (photograph) (category Photographs in the Metropolitan Museum of Art)
    blue-green (1909), and yellow-green-black (1904–1909; uncertain).: 24  Using different proportions of pigments in each gum process, Steichen was able to...
    12 KB (1,376 words) - 22:38, 9 January 2025
  • Thumbnail for HMMER
    Smith-Waterman algorithm for aligning two sequences. A profile HMM is a variant of an HMM relating specifically to biological sequences. Profile HMMs turn...
    15 KB (1,612 words) - 09:00, 27 May 2025
  • Thumbnail for One-letter word
    have an uncertain status in language theory, dictionaries and social usage. They are sometimes used as book titles, and have been the subject of literary...
    76 KB (7,749 words) - 11:41, 15 May 2025
  • Koorai silk saree (category Culture of Tamil Nadu)
    unique weaving patterns and cultural significance. It is produced by the Sāliyan weaving community using a blend of silk and cotton, and is typically characterized...
    11 KB (1,092 words) - 05:49, 4 June 2025
  • Thumbnail for Reptile
    pterosaurs. The composition of Euryapsida was uncertain. Ichthyosaurs were, at times, considered to have arisen independently of the other euryapsids, and...
    139 KB (14,930 words) - 16:33, 5 June 2025
  • Thumbnail for Rock-a-bye Baby
    that the age of the words is uncertain, and that "imaginations have been stretched to give the rhyme significance". They list a variety of claims that...
    10 KB (1,141 words) - 08:56, 19 May 2025
  • Thumbnail for Nine men's morris
    This variant (also called ten men's morris) was invented by Emanuel Lasker, chess world champion from 1894 to 1921. It is based on the rules of nine men's...
    19 KB (2,261 words) - 04:50, 1 June 2025
  • Germanic name (category Names of Germanic origin)
    in -rad. Förstemann 1900:875. names with this second element are uncertain, most of the candidates could contain the simple suffix -ing. Förstemann 1900:877...
    59 KB (1,406 words) - 22:08, 7 April 2025
  • Thumbnail for Coat of arms of Ukraine
    cultural and heraldic significance for Ukraine). On 25 February 1918, the Central Rada (parliament) adopted it as the coat of arms of the short-lived Ukrainian...
    32 KB (3,025 words) - 14:59, 25 May 2025
  • Thumbnail for Epidermolysis bullosa dystrophica
    require feeding tubes for nutrition. They also have iron-deficiency anemia of uncertain origin, which leads to chronic fatigue.[citation needed] Open wounds...
    13 KB (1,245 words) - 20:45, 29 May 2025
  • now known as the Paleo-Hebrew alphabet, has been largely preserved in a variant form as the Samaritan alphabet, and is still used by the Samaritans. The...
    123 KB (5,372 words) - 19:15, 2 June 2025
  • Thumbnail for Sheva Brachot
    a harmonious unit, the blessings are actually a mosaic of Biblical origination. It is uncertain who composed the benedictions in the form recorded in the...
    11 KB (906 words) - 03:06, 25 October 2024
  • Thumbnail for Gilbert's syndrome
    of the skin or whites of the eyes) may occur. Gilbert syndrome is due to a genetic variant in the UGT1A1 gene which results in decreased activity of the...
    41 KB (4,215 words) - 04:22, 2 June 2025
  • Thumbnail for Enigma-M4
    than that of the other Enigma variants with only three rotors and therefore could not be broken by the Allies for a long time. All parts of the German...
    50 KB (6,425 words) - 20:56, 12 September 2024