• Thumbnail for AP-1 transcription factor
    protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress...
    42 KB (4,614 words) - 14:25, 30 July 2025
  • Thumbnail for Transcription factor Jun
    Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...
    46 KB (5,537 words) - 04:52, 15 July 2025
  • Thumbnail for Transcription factor
    molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information...
    75 KB (8,351 words) - 22:53, 24 June 2025
  • The AP-1 binding site, also known as the AP-1 promoter site, is a DNA sequence to which AP-1 transcription factors are able to bind. The AP-1 binding...
    982 bytes (113 words) - 15:58, 19 September 2022
  • Thumbnail for JunD
    JunD (category Transcription factors)
    with ATF3, MEN1, DNA damage-inducible transcript 3 and BRCA1. AP-1 (transcription factor) GRCh38: Ensembl release 89: ENSG00000130522 – Ensembl, May 2017...
    13 KB (1,561 words) - 17:05, 17 July 2025
  • Thumbnail for Pardaxin
    JNK is phosphorylated, which leads to the phosphorylation of AP-1 (transcription factor consisting of cFOS and Cjun). This results in the activation of...
    8 KB (935 words) - 04:17, 28 May 2025
  • Thumbnail for JUNB
    JUNB (category Transcription factors)
    growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'. JUNB has been shown to interact with BRCA1, and SMAD3. AP-1 (transcription factor) GRCh38:...
    9 KB (1,199 words) - 04:20, 15 July 2025
  • Thumbnail for BATF (gene)
    BATF (gene) (category Transcription factors)
    basic leucine zipper (bZIP) protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization...
    7 KB (885 words) - 15:47, 17 July 2025
  • Thumbnail for SV40
    of synthesis. This is done by binding (dimerization) with the AP-1 transcription factor to give a primary transcript that is 3' polyadenylated and 5'...
    21 KB (2,522 words) - 18:30, 17 July 2025
  • Thumbnail for ATF1
    AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription factor, which...
    11 KB (1,380 words) - 03:53, 15 July 2025
  • Thumbnail for Lithium (medication)
    mesencephalic astrocyte-derived neurotrophic factor (MANF), another neurotrophic factor, via the AP-1 transcription factor. MANF is able to regulate proteostasis...
    105 KB (11,204 words) - 21:56, 15 July 2025
  • Thumbnail for Cocaine
    Psychiatry. 27 (1): 624–639. doi:10.1038/s41380-021-01256-1. PMC 8960411. PMID 34453125. Hope BT (May 1998). "Cocaine and the AP-1 transcription factor complex"...
    201 KB (20,633 words) - 06:04, 25 July 2025
  • Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. First...
    3 KB (310 words) - 08:38, 6 November 2024
  • Thumbnail for USF1
    stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene. The upstream stimulatory factor (USF) gene encodes a transcription factor USF that...
    41 KB (4,563 words) - 09:19, 18 July 2025
  • Thumbnail for FOSL2
    FOSL2 (category Transcription factors)
    dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators...
    5 KB (676 words) - 05:50, 19 July 2025
  • Thumbnail for FOSL1
    FOSL1 (redirect from Fra-1)
    dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators...
    8 KB (1,074 words) - 16:37, 17 July 2025
  • Thumbnail for FOSB
    FOSB (category Transcription factors)
    of the JUN family (e.g., c-Jun, JunD), thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators...
    57 KB (7,191 words) - 16:36, 17 July 2025
  • Thumbnail for Transcription factor Sp1
    Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene...
    30 KB (3,441 words) - 08:44, 5 February 2025
  • AP1 (redirect from AP 1)
    or AP-1 may refer to: Activator protein 1, dimeric transcription factor Adaptor protein 1, tetrameric clathrin-associated complex Autopista AP-1, a Spanish...
    535 bytes (99 words) - 06:12, 19 December 2022
  • ATF/CREB (category Transcription factors)
    the transcription factors assigned to this group, some are more related to CREB-like, factors, whereas other exhibit closer similarity with the AP-1 transcription...
    2 KB (225 words) - 20:32, 13 October 2022
  • This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. It was assembled by manual curation. More detailed...
    374 KB (81 words) - 11:17, 3 January 2025
  • Thumbnail for BZIP domain
    factors affecting reproductive functions, and several other phenomena that affect human health. AP-1 fos/jun heterodimer that forms a transcription factor...
    7 KB (663 words) - 00:42, 13 March 2024
  • Thumbnail for Protein c-Fos
    Protein c-Fos (category Transcription factors)
    (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the...
    26 KB (3,991 words) - 05:29, 10 July 2024
  • Thumbnail for General transcription factor
    General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific...
    12 KB (1,319 words) - 16:40, 17 July 2025
  • the -60 position. There are several AP-1 transcription factor binding sites in the viral LTRs. The closest AP-1 binding site is bound by the Jun and...
    30 KB (3,765 words) - 07:43, 19 July 2025
  • Thumbnail for T-box transcription factor T
    T-box transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription...
    36 KB (4,178 words) - 20:39, 16 July 2025
  • Thumbnail for NK2 homeobox 1
    1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the NKX2-1 gene. Thyroid transcription factor-1...
    19 KB (2,210 words) - 09:49, 18 July 2025
  • Thumbnail for ETS transcription factor family
    Transformation Specific) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, 27 in the...
    10 KB (1,058 words) - 23:17, 24 May 2025
  • Thumbnail for Proliferative fasciitis and proliferative myositis
    Diagnostic Pathology. 33 (1): 50–9. doi:10.1053/j.semdp.2015.09.007. PMID 26490572. "FOS Fos proto-oncogene, AP-1 transcription factor subunit [Homo sapiens...
    20 KB (2,282 words) - 13:50, 3 December 2023
  • Thumbnail for GATA transcription factor
    The GATA transcription factor family consists of six DNA-binding proteins (GATA1-6) that regulates transcription of DNA due to their ability to bind to...
    8 KB (995 words) - 06:20, 25 July 2024