• Thumbnail for Chloride channel
    Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many different ions, but are named...
    21 KB (2,534 words) - 10:00, 22 May 2025
  • Chloride channel openers refer to a specific category of drugs designed to modulate chloride channels in the human body. Chloride channels are anion-selective...
    35 KB (4,517 words) - 18:48, 17 July 2025
  • Thumbnail for Fainting goat
    goat's chloride channel. A goat demonstrating the disease had a +47 mV shift in the channel activation, which created less open chloride channels located...
    19 KB (2,407 words) - 18:23, 16 July 2025
  • Thumbnail for Voltage-gated ion channel
    potassium (K+), calcium (Ca2+), and chloride (Cl−) ions have been identified. The opening and closing of the channels are triggered by changing ion concentration...
    21 KB (2,298 words) - 09:52, 22 May 2025
  • Elexacaftor/tezacaftor/ivacaftor is composed of a combination of ivacaftor, a chloride channel opener, and elexacaftor and tezacaftor, CFTR modulators. It is approved...
    38 KB (3,104 words) - 20:42, 29 May 2025
  • Thumbnail for Ion channel
    ion channels. These are classified by the channel on which they act:[citation needed] Calcium channel openers, such as Bay K8644 Chloride channel openers...
    52 KB (6,010 words) - 00:37, 18 July 2025
  • Thumbnail for Neurotoxin
    inhibit the conductance of chloride channels. Ingestion of lethal volumes of Cltx results in paralysis through this ion channel disruption. Similar to botulinum...
    90 KB (9,743 words) - 01:35, 6 July 2025
  • Thumbnail for Calcium-dependent chloride channel
    Calcium-Dependent Chloride Channel (Ca-ClC) proteins (or calcium-activated chloride channels (CaCCs), are heterogeneous groups of ligand-gated ion channels for chloride...
    14 KB (1,531 words) - 02:20, 29 November 2023
  • A chloride channel blocker is a type of drug which inhibits the transmission of ions (Cl−) through chloride channels. Niflumic acid is a chloride channel...
    4 KB (486 words) - 19:40, 22 December 2024
  • Thumbnail for Laxative
    Solutions of polyethylene glycol and electrolytes (sodium chloride, sodium bicarbonate, potassium chloride, and sometimes sodium sulfate) are used for whole bowel...
    25 KB (2,458 words) - 04:22, 15 July 2025
  • insecticide binding at the GABAA site in the GABA-gated chloride channel (IRAC group 2A), which inhibits chloride flow into the nerve.: 257  Other examples include...
    18 KB (2,012 words) - 17:08, 2 July 2025
  • of ionic chlorides include potassium chloride (KCl), calcium chloride (CaCl2), and ammonium chloride (NH4Cl). Examples of covalent chlorides include methyl...
    18 KB (1,753 words) - 16:26, 19 July 2025
  • Thumbnail for Potassium channel
    S2CID 5694563. Hille, Bertil (2001). "Chapter 5: Potassium Channels and Chloride Channels". Ion channels of excitable membranes. Sunderland, Mass: Sinauer. pp...
    57 KB (5,809 words) - 23:06, 30 July 2025
  • Thumbnail for Sodium channel
    Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily...
    53 KB (5,658 words) - 02:27, 4 August 2025
  • Thumbnail for Epithelial sodium channel
    sodium chloride (NaCl). 4-propylphenyl 2-furoate is a compound that was discovered to activate proteolyzed ENaC. Studies show that the ENaC channel is permeable...
    25 KB (2,992 words) - 02:29, 19 February 2025
  • Thumbnail for Cystic fibrosis
    passage of chloride ions. A mutation in the CFTR gene can impair the normal function of chloride channels, leading to abnormal transport of chloride ions and...
    166 KB (18,619 words) - 17:10, 6 August 2025
  • Thumbnail for Avermectin
    mostly by enhancing the effects of glutamate at the glutamate-gated chloride channel that is specific to protostome invertebrates, with minor effects on...
    17 KB (1,838 words) - 05:14, 30 May 2025
  • have mutations in the chloride gene but rather in the alpha-subunit of the voltage gated sodium channel (SCN4A). Like chloride channel mutations, patients...
    26 KB (3,125 words) - 06:37, 19 July 2025
  • concentration of chloride that is excreted in sweat. It is used to screen for cystic fibrosis (CF). Due to defective chloride channels (CFTR), the concentration...
    8 KB (882 words) - 13:43, 17 April 2025
  • Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane...
    28 KB (3,041 words) - 15:00, 3 August 2025
  • Thumbnail for Ligand-gated ion channel
    Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...
    29 KB (2,607 words) - 05:16, 26 May 2025
  • calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, which...
    10 KB (760 words) - 05:44, 26 May 2025
  • magnesium chloride, magnesium lactate, and magnesium aspartate, may increase or enhance the effects of calcium channel blockade. N-type calcium channels are...
    31 KB (3,456 words) - 00:13, 24 June 2025
  • Thumbnail for BK channel
    channels (big potassium), are large conductance calcium-activated potassium channels, and is also known as BKCa, Maxi-K, slo1, or Kca1.1. BK channels...
    33 KB (3,794 words) - 21:58, 15 June 2025
  • Thumbnail for Afoxolaner
    gamma-aminobutyric acid) and other ligand-gated chloride channels. Isoxazolines, among the chloride channel modulators, bind to a distinct and unique target...
    14 KB (1,134 words) - 04:04, 15 July 2025
  • Thumbnail for Glutamate (neurotransmitter)
    In arthropods and nematodes, glutamate stimulates glutamate-gated chloride channels. The β subunits of the receptor respond with very high affinity to...
    20 KB (2,185 words) - 08:27, 3 April 2025
  • Thumbnail for CLIC4
    CLIC4 (category Ion channels)
    Chloride intracellular channel 4, also known as CLIC4,p644H1,HuH1, is a eukaryotic gene. Chloride channels are a diverse group of proteins that regulate...
    10 KB (1,251 words) - 04:00, 15 July 2025
  • Gardner, Phyllis; Schulman, Howard (1989), "Response: Is Regulation of a Chloride Channel in Lymphocytes Affected in Cystic Fibrosis?", Science, 246 (4933):...
    45 KB (4,089 words) - 01:26, 29 July 2025
  • blocks small-conductance chloride channels; Maurotoxin from the venom of the Tunisian Scorpio maurus blocks potassium channels. Some antimicrobial peptides...
    16 KB (1,572 words) - 12:49, 3 April 2025
  • Thumbnail for Cystic fibrosis transmembrane conductance regulator
    ion channel protein that conducts chloride and bicarbonate ions across epithelial cell membranes. Mutations of the CFTR gene affecting anion channel function...
    62 KB (6,535 words) - 17:03, 16 July 2025