dendritic cell-based cancer vaccine is an innovation in therapeutic strategy for cancer patients. Dendritic cells (DCs) are antigen presenting cells for...

melanoma cell lines, failed phase III clinical trials. Another cell-based vaccine strategy involves autologous dendritic cells (dendritic cells derived...

A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system. A DC's main function is to process...

PMID 11481463. Palucka K, Banchereau J (July 2013). "Dendritic-cell-based therapeutic cancer vaccines". Immunity. 39 (1): 38–48. doi:10.1016/j.immuni.2013...

Cancer vaccine Vaccine can be composed of killed tumor cells, recombinant tumor antigens, or dendritic cells incubated with tumor antigens (dendritic...

Thielemans K, Breckpot K (February 2015). "mRNA-based dendritic cell vaccines". Expert Review of Vaccines. 14 (2): 161–76. doi:10.1586/14760584.2014.957684...

forms of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural...

A DNA vaccine is a type of vaccine that transfects a specific antigen-coding DNA sequence into the cells of an organism as a mechanism to induce an immune...

manufacture. Many innovative vaccines are also in development and use. Dendritic cell vaccines combine dendritic cells with antigens to present the antigens...

antigen-specific T-cell responses. Whole-cell vaccines have been researched in the fields of bacterial infectious disease (as an inactivated vaccine) and cancer (as...

experimental autologous dendritic cell COVID‑19 vaccine kit where the vaccine is prepared and incubated at the point-of-care using cells from the intended recipient...

Kiessling R (June 2012). "Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines". Cancer Immunology, Immunotherapy. 61 (6): 827–838. doi:10...

vaccine can be made from dissembled viral particles in cell culture or recombinant DNA expression, in which case it is a recombinant subunit vaccine....

|journal= (help) Cancer Research UK (2020-11-10). "A Cancer Research UK Phase I Trial of AST-VAC2 (Allogeneic Dendritic Cell Vaccine) Administered Weekly...

immune cells by releasing cytokines. They are considered essential in B cell antibody class switching, breaking cross-tolerance in dendritic cells, in the...

population, followed by monocytes, and only a small percentage of dendritic cells. These cells can be extracted from whole blood using ficoll, a hydrophilic...

Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells". Cancer Immunology Research. 6 (9): 1082–1092. doi:10.1158/2326-6066...

IDH inhibitors like Ivosidenib, to the recently approved Dendritic cell-based cancer vaccine approach. Treatment using immunotherapy is another promising...

Sipuleucel-T, a dendritic cell based vaccine for prostate cancer. Bacillus Calmettle-Guerin (TheraCys) is a live attenuated vaccine which makes use of...

Cancer vaccine targeting CD4+ T cells is a type of vaccine used to treat existing cancer. Cancerous cells usually cannot be recognized by the human immune...

vector vaccine is a vaccine that uses a viral vector to deliver genetic material (DNA) that can be transcribed by the recipient's host cells as mRNA...

recognition of tumors by dendritic cells. DC-SIGN is also a potential engineering target for dendritic cell based cancer vaccine. This molecule is involved...

BioNTech, which developed one of the major vaccines against COVID-19. His main fields of research are cancer research and immunology. Şahin's family, originally...

PMID 11099314. Avigan D, Rosenblatt J, Kufe D (June 2012). "Dendritic/tumor fusion cells as cancer vaccines". Seminars in Oncology. 39 (3): 287–95. doi:10.1053/j...

Recent applications of SeV-based vectors include the reprogramming of somatic cells into induced pluripotent stem cells and vaccine creation. For vaccination...

malignant melanoma and renal cell carcinoma. Sipuleucel-T is a vaccine-like strategy for prostate cancer in which dendritic cells from the patient are loaded...

conjunction with the vaccine can greatly increase the innate immune response to the antigen by augmenting the activities of dendritic cells, lymphocytes, and...

were viral vector-based. Further, compared to traditional vaccines, the intracellular antigen expression enabled by viral vector vaccines offers more robust...

GP (2015). "Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells". Science. 348...

somatic cancer mutations in an individual tumor. Carcinogenesis is largely driven by changes in the DNA sequence of the genomes of cancer cells. This process...