• Thumbnail for Post-translational modification
    In molecular biology, post-translational modification (PTM) is the covalent process of changing proteins following protein biosynthesis. PTMs may involve...
    33 KB (3,238 words) - 16:28, 25 May 2025
  • (posttranslational modifications, such as phosphorylation or sequestration) or by means of irreversible events (proteolysis). Post-translational modification Wolfgang...
    1 KB (74 words) - 01:56, 1 May 2024
  • Thumbnail for Nucleosome
    mid-1960s, histone modifications have been predicted to affect transcription. The fact that most of the early post-translational modifications found were concentrated...
    56 KB (6,666 words) - 13:34, 23 May 2025
  • Thumbnail for Protein biosynthesis
    the protein can undergo further maturation through different post-translational modifications, which can alter the protein's ability to function, its location...
    40 KB (4,408 words) - 11:19, 2 June 2025
  • Thumbnail for Protein primary structure
    peptide bond. Additionally, the protein can undergo a variety of post-translational modifications, which are briefly summarized here. The N-terminal amino group...
    20 KB (2,315 words) - 00:24, 14 June 2025
  • Thumbnail for Proteomics
    post-translational modifications. many transcripts give rise to more than one protein, through alternative splicing or alternative post-translational...
    78 KB (9,070 words) - 20:27, 9 June 2025
  • ubiquitin-related modifier protein modification of BMAL1 has also been proposed as another level of post-translational regulation. Circadian oscillators...
    37 KB (4,473 words) - 07:35, 3 June 2024
  • Thumbnail for Enzyme
    internal environment in living organisms.: 141  Examples of post-translational modification include phosphorylation, myristoylation and glycosylation.: 149–69 ...
    99 KB (10,092 words) - 13:18, 17 June 2025
  • Thumbnail for Gene expression
    including the transcription, RNA splicing, translation, and post-translational modification of a protein. Regulation of gene expression gives control over...
    104 KB (11,629 words) - 17:28, 3 June 2025
  • Thumbnail for Microtubule
    "The chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functions". Cytoskeleton...
    63 KB (7,911 words) - 10:11, 17 June 2025
  • Thumbnail for Arginylation
    Arginylation is a post-translational modification in which proteins are modified by the addition of arginine (Arg) at the N-terminal amino group or side...
    21 KB (2,495 words) - 23:15, 20 February 2024
  • H3K27ac (category Post-translational modification)
    tails are the site of the post-translational modifications, such as the one seen in H3K36me3. The posttranslational modification of histone tails by either...
    20 KB (1,702 words) - 03:35, 2 June 2025
  • The central dogma of molecular biology deals with the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and...
    23 KB (2,707 words) - 11:19, 25 May 2025
  • Thumbnail for Histone H3
    nucleosome core and is susceptible to post-translational modification that influence cellular processes. These modifications include the covalent attachment...
    6 KB (623 words) - 21:05, 23 May 2025
  • are dual-specificity tyrosine kinases. This corroborates the post-translational modification predictions. "KIAA0232 KIAA0232 [Homo sapiens (human)] - Gene...
    5 KB (436 words) - 12:51, 23 November 2024
  • Protein acetylation (category Post-translational modification)
    acetylated mammalian proteins. Acetylation occurs as a co-translational and post-translational modification of proteins, for example, histones, p53, and tubulins...
    42 KB (4,899 words) - 05:43, 2 June 2025
  • Thumbnail for NBPF10
    threonine content which may make the protein less susceptible to post-translational modification.[citation needed] GRCh38: Ensembl release 89: ENSG00000162825...
    3 KB (324 words) - 13:06, 26 February 2024
  • Thumbnail for Escherichia coli
    to allow disulphide-bonds to form, while proteins requiring post-translational modification such as glycosylation for stability or function have been expressed...
    108 KB (11,158 words) - 20:21, 15 June 2025
  • Thumbnail for PDZ domain
    researchers have seen post-translational modifications activate PDZ domain activity but these cases are few. Another post-translational modification that can regulate...
    34 KB (3,565 words) - 02:04, 3 December 2023
  • Thumbnail for FOX proteins
    localization, and stability depends critically on post-translational modifications (PTMs). These modifications, including phosphorylation, methylation and acetylation...
    27 KB (3,132 words) - 05:42, 2 June 2025
  • Thumbnail for Proinsulin
    remain connected by disulfide bonds.[citation needed] The post translational modification of proinsulin to mature insulin only occurs in the beta cells...
    17 KB (1,731 words) - 17:00, 26 November 2024
  • Thumbnail for Protein phosphorylation
    Protein phosphorylation is a reversible post-translational modification of proteins in which an amino acid residue is phosphorylated by a protein kinase...
    67 KB (7,955 words) - 05:53, 8 May 2025
  • Thumbnail for Lipid-anchored protein
    Lipid-anchored protein (category Post-translational modification)
    morphology. Furthermore, protein prenylation is a reversible post-translational modification to the cell membrane. This dynamic interaction of prenylated...
    19 KB (2,151 words) - 16:00, 3 March 2025
  • Thumbnail for Formylation
    Formylation (category Post-translational modification)
    formylation may block other post-translational modifications. Formylation is detected most frequently on 19 different modification sites on Histone H1. The...
    25 KB (2,838 words) - 19:16, 23 November 2024
  • Thumbnail for Histone
    Histone (redirect from Histone modification)
    end of the amino acid structure - this being the location of post-translational modification (see below). Archaeal histone only contains a H3-H4 like dimeric...
    91 KB (10,379 words) - 13:53, 22 May 2025
  • Thumbnail for Dishevelled
    DEP and C-terminus of DVL. There are three main types of DVL post-translational modification - phosphorylation, ubiquitination, and methylation. Phosphorylation...
    12 KB (1,387 words) - 06:32, 20 May 2025
  • Thumbnail for Phosphocholine
    Phosphocholine (category Post-translational modification)
    et al. (September 2007). "Identification of a novel mammalian post-translational modification, phosphocholine, on placental secretory polypeptides". Journal...
    4 KB (294 words) - 10:44, 23 June 2024
  • Carboxylation (category Post-translational modification)
    DP, Stevens RD, Wright DJ, Stafford DW (1995). "Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate"...
    8 KB (859 words) - 01:45, 13 February 2025
  • Thumbnail for Amino acid
    Non-proteinogenic or modified amino acids may arise from post-translational modification or during nonribosomal peptide synthesis. The carbon atom next...
    94 KB (10,037 words) - 18:20, 18 June 2025
  • Thumbnail for Post-transcriptional modification
    polyadenylation. Post-translational modification RNA editing RNA-Seq Kiss T (July 2001). "Small nucleolar RNA-guided post-transcriptional modification of cellular...
    11 KB (1,432 words) - 23:35, 24 July 2024