Magnetic sequencing is a single-molecule sequencing method in development. A DNA hairpin, containing the sequence of interest, is bound between a magnetic...

in RNA sequencing technology have addressed some of these limitations. New methods such as next-generation sequencing (NGS) and single-molecule real-time...

templates or single DNA molecules in a flow cell. This design is very different from that of Sanger sequencing—also known as capillary sequencing or first-generation...

spectroscopy Magnetic tweezers Optical tweezers Raman spectroscopy Scanning probe microscopy Single molecule real time sequencing Single-molecule magnet Single-particle...

single cell sequencing, bulk RNA sequencing, 3' mRNA-sequencing, in situ sequencing of fixed tissue, and native RNA molecule sequencin g with single-molecule...

computer-controlled flowcell/fluidics system. Polony sequencing is generally performed on paired-end tags library that each molecule of DNA template is of 135 bp in length...

essentially a single molecule, the mole is still used to express the number of atoms bound together, rather than a count of molecules. Thus, common chemical...

hybridizing large numbers of molecules (differing hybridizing temperatures). RNA-Seq transcriptomics by next gen sequencing will mean these barriers no...

aberration can be observed using single-cell sequencing. Single-cell transcriptomics uses sequencing techniques similar to single-cell genomics or direct detection...

Uhlen and Pål Nyren by combining the solid phase sequencing method using streptavidin coated magnetic beads with recombinant DNA polymerase lacking 3´to...

Kinzler KW, Vogelstein B (July 2003). "Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations"...

from large amounts of raw data. In the field of genetics, it aids in sequencing and annotating genomes and their observed mutations. Bioinformatics includes...

technology RNA fragments are directly attached to a magnetic bead through an adapter, while for Illumina sequencing, the RNA fragments are firstly ligated to the...

isolate any biotinylated molecule. This is frequently used in DNA/RNA binding protein studies, sequencing, and to prepare single stranded templates. Gene...

sample, the masses of particles and of molecules, and to elucidate the chemical identity or structure of molecules and other chemical compounds. In a typical...

By running these truncated RNA molecules on a gel, the nucleotide of interest can be identified against a sequencing experiment Site directed incorporation...

Meni; Slavov, Nikolai (March 2023). "Sampling the proteome by emerging single-molecule and mass spectrometry methods". Nature Methods. 20 (3): 339–346. doi:10...

University of Technology. He is known for his research on carbon nanotubes, single-molecule biophysics, and nanobiology. Born in Haren, Groningen in 1959, Dekker...

Similar to Ribo-seq, Ribo-tRNA-seq captures tRNA molecules in ribosomes for library preparation before sequencing Degradomics Proteomics Translatome Zhao J,...

efficiently by streptavidin-coated magnetic beads, and chromatin interaction data can be obtained by direct sequencing of the Hi-C library. Analyses of...

bulk and single-cell samples and is particularly powerful for single-cell proteomics. Tandem mass spectrometry can be used for protein sequencing. When intact...

that they might be composed of a single type of (very large) molecule. The term "protein" to describe these molecules was proposed by Mulder's associate...

portal DNA sequencing Sequencing by ligation Single Molecule Real Time Sequencing Jay Shendure et al. (2005) Accurate Multiplex Polony Sequencing of an Evolved...

CAPP-Seq (cancer personalized profiling by deep sequencing) is a next-generation sequencing based method used to quantify circulating DNA in cancer (ctDNA)...

the charge on many of the molecules found in nucleic acids and protein. This is also the key method for Sanger sequencing. Fluorescent-labeled DNA fragments...

In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody...

immunoglobulin (IVIg) Magnetic immunoassay Microantibody Monoclonal antibody Neutralizing antibody Optimer Ligand Secondary antibodies Single-domain antibody...

composition and purity of molecules synthesized by DMF are often determined utilizing classic analytical techniques. Nuclear magnetic resonance (NMR) spectroscopy...

persistence length of DNA as shown by magnetic tweezers experiments, which allow studying condensation of a single DNA molecule by a DNA binding protein. However...

after bisulfite sequencing. This allows simultaneous analysis of the nucleosome footprint and endogenous methylation on the same DNA molecules. In addition...