Ceritinib (INN, trade name Zykadia /zaɪˈkeɪdiːə/ zy-KAY-dee-ə) is a prescription-only drug used for the treatment of non-small cell lung cancer (NSCLC)...

and targeting a broader set of resistance mutations. As such, Novartis' ceritinib was approved by the FDA in April 2014 for treatment of NSCLC. It provided...

ALK inhibitors crizotinib, or its successors alectinib, brigatinib, and ceritinib. Those treated with ALK inhibitors who relapse can then be treated with...

in Rwanda Living room, Dining room, Kitchen, in Japanese accommodation Ceritinib or LDK378, a cancer drug This disambiguation page lists articles associated...

brand name Xalkori and Crizalk that targets the EML4/ALK fusion gene. Ceritinib is a second generation targeted therapy (FDA approved in 2014), manufactured...

certain resistance mutations that develop during treatment with crizotinib. Ceritinib demonstrates clinical activity (including treating the brain) in ROS1+...

Sorafenib Sunitinib Tivozanib Toceranib Vandetanib ALK Alectinib Brigatinib Ceritinib Crizotinib Ensartinib Lorlatinib RET inhibitors: Entrectinib (ALK, ROS1...

for metastatic disease or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease. Approval was...

days of treatment. Treatment must be continued indefinitely at present. Ceritinib was approved by the FDA in April 2014 for the treatment of patients with...

as those increasing the AUC of digoxin to ≥1.25-fold); telithromycin ceritinib mibefradil (used for the treatment of hypertension and chronic angina...

crizotinib benefited from second-generation ALK inhibitors including ceritinib, alectinib and brigatinib. Resistance to ALK inhibitors can occur with...

Vemurafenib L01EC02 Dabrafenib L01EC03 Encorafenib L01ED01 Crizotinib L01ED02 Ceritinib L01ED03 Alectinib L01ED04 Brigatinib L01ED05 Lorlatinib L01EE01 Trametinib...

metronidazole (antibiotic and antiprotozoal medication) phenylbutazone Weak ceritinib quercetin (a plant-based flavonol) Unspecified potency antihistamines...

the development of multiple new drug launches, for example nilotinib, ceritinib, panobinostat, and Entresto. Briner left Novartis in late 2022, and is...

Sorafenib Sunitinib Tivozanib Toceranib Vandetanib ALK Alectinib Brigatinib Ceritinib Crizotinib Ensartinib Lorlatinib RET inhibitors: Entrectinib (ALK, ROS1...

Pembrolizumab Merck Sharp & Dohme microsatellite instability-high tumors Ceritinib Novartis Pharmaceuticals ALK-positive, metastatic non-small cell lung...

retreatment with crizotinib (1 case) or a second generation ALK inhibitor, ceritinib (1 case). A study of 14 pediatric patients with metastatic or inoperable...

CH5424802 (Chugai Pharmaceutical Co.) ASP3026 (Astellas Pharma Inc.) Ceritinib (LDK378, Novartis Pharmaceuticals) AP26113 (Ariad Pharmaceuticals) Crizotinib...