direct and indirect Coombs tests, also known as antiglobulin test (AGT), are blood tests used in immunohematology. The direct Coombs test detects antibodies...
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Robert Royston Amos Coombs (9 January 1921 – 25 January 2006) was a British immunologist, co-discoverer of the Coombs test (1945) used for detecting antibodies...
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A test tube, also known as a culture tube or sample tube, is a common piece of laboratory glassware consisting of a finger-like length of glass or clear...
8 KB (1,113 words) - 23:48, 29 December 2024
Titer (redirect from Titer testing)
reported to have an "indirect Coombs titer" of 16. This means that the patient's serum gives a positive indirect Coombs test at any dilution down to 1/16...
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with ceftriaxone seroconverted from a negative to a positive direct Coombs' test result. No clinical adverse reactions representing hemolytic anemia were...
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Hypersensitivity (redirect from Gell-Coombs classification)
involved. According to this system, known as the Gell and Coombs classification or Gell-Coombs's classification, there are four types of hypersensitivity...
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cord blood. In some cases, the direct Coombs will be negative but severe, even fatal HDN can occur. An indirect Coombs needs to be run in cases of anti-C...
39 KB (4,575 words) - 09:17, 21 April 2025
present in a patient, the Coombs test, also known as the antiglobulin test, is performed. There are two types of Coombs tests, direct and indirect; more...
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Phlebotomy (category Blood tests)
people trained to draw blood mostly from veins for clinical or medical testing, transfusions, donations, or research. Blood is collected primarily by...
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Venipuncture (category Blood tests)
accurate laboratory results. Any error in collecting the blood or filling the test tubes may lead to erroneous laboratory results. Venipuncture is one of the...
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Hemolytic jaundice (section Screening laboratory tests)
high serum lactate dehydrogenase and negative anti-RBC antibodies and Coombs test. Clinically, dark urine from hemoglobinuria may be observed because the...
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jaundice during the first week of life. Testing Coombs - after birth, the newborn will have a direct Coombs test run to confirm antibodies attached to the...
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of measure by volume. Coombs test, an aid to medical diagnosis. Coomb Teak or Gmelina arborea, a medicinal tree. Deeping Coomb, a fictional deep valley...
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development of multiple sclerosis. Hematologic: Hemolytic anemia (direct Coombs test is positive) and various cytopenias, and bleeding (caused by thrombocytopenia)...
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cells. An antiglobulin test, also known as a Coombs test, is a type of blood test used in immunohematology. An antiglobulin test may either be direct (e...
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hemoglobin binding protein haptoglobin, and the direct Coombs test (also called direct antiglobulin test or DAT) to evaluate complement factors and/or antibodies...
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prevent Rh disease. Indirect Coombs test (AGT) to assess risk of hemolytic disease of the newborn Rapid plasma reagin test to screen for syphilis Rubella...
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weeks. Coombs - after birth baby will have a direct coombs test run to confirm antibodies attached to the infant's red blood cells. This test is run from...
30 KB (3,558 words) - 21:03, 29 May 2025
or cord blood gives a positive direct Coombs test and the maternal blood gives a positive indirect Coombs test) Hemolytic disease of the newborn (ABO)...
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: 120 In 1945, Robin Coombs, A.E. Mourant and R.R. Race published a description of the antiglobulin test (also known as the Coombs test). Previous research...
51 KB (6,442 words) - 03:48, 5 May 2025
Antibody (section Production and testing)
tests. Antibodies directed against red blood cell surface antigens in immune mediated hemolytic anemia are detected with the Coombs test. The Coombs test...
126 KB (13,987 words) - 23:29, 29 May 2025
haemofelis to red blood cell membranes is often associated with positive Coombs test results, meaning IgG antibodies have become bound to red blood cells...
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Blood transfusion (section Processing and testing)
tested against a drop of 3–5% suspension of donor cells in a test tube and spun in a serofuge. Agglutination or hemolysis (i.e., positive Coombs test)...
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hereditary spherocytosis, but the former would have a positive direct Coombs test and the latter would not. The misshapen but otherwise healthy red blood...
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discovered the MN blood group system, and the P system. Development of the Coombs test in 1945, the advent of transfusion medicine, and the understanding of...
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A vacutainer blood collection tube is a sterile glass or plastic test tube with a colored rubber stopper creating a vacuum seal inside of the tube, facilitating...
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Hereditary spherocytosis (section Laboratory testing)
binding test Osmotic fragility test Acidified glycerol lysis test A negative direct antiglobin test (Coombs test) The common findings of lab testing in setting...
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laboratory studies, including blood tests for complete blood count, TORCH infections, haemoglobin, viral cultures and Coombs test. A skin biopsy may be useful...
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leukocytoclastic angiitis). An alternative to biopsy can be an angiogram (x-ray test of the blood vessels). It can demonstrate characteristic patterns of inflammation...
31 KB (2,435 words) - 19:01, 28 April 2025
erythrocytes in advance of performing an immunological test such as a complement-fixation test or a Coombs test. The antibodies are bound to the cells in their...
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