• Thumbnail for Decapping complex
    mRNA decapping complex is a protein complex in eukaryotic cells responsible for removal of the 5' cap. The active enzyme of the decapping complex is the...
    20 KB (2,480 words) - 23:17, 23 May 2025
  • Thumbnail for Cap binding complex
    message from decapping. When translationally repressed or marked for decay by various mechanisms the 5' cap is bound by the mRNA decapping enzyme DCP2...
    3 KB (347 words) - 06:29, 4 January 2023
  • Thumbnail for Messenger RNA
    destabilize the cap binding complex. The message is then subject to degradation by either the exosome complex or the decapping complex. In this way, translationally...
    52 KB (6,275 words) - 02:08, 10 July 2025
  • processes take significant time. Decapping of a 7-methylguanylate-capped mRNA is catalyzed by the decapping complex made up of at least Dcp1 and Dcp2...
    17 KB (2,017 words) - 17:07, 11 July 2025
  • Thumbnail for DCP2
    mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene. DCP2 is a key component of an mRNA-decapping complex required for removal...
    7 KB (799 words) - 21:38, 2 December 2023
  • Thumbnail for Nudix hydrolase
    contains the catalytic amino acids. NUDIX hydrolases include Dcp2 of the decapping complex, ADP-ribose diphosphatase, MutT, ADPRase, Ap4A hydrolases, RppH, and...
    4 KB (380 words) - 09:53, 10 September 2024
  • Thumbnail for DCP1A
    protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated...
    8 KB (874 words) - 20:18, 27 July 2022
  • inhibit poly(A) tail removal. Once the poly(A) tail is removed, the decapping complex removes the 5′ cap, leading to a degradation of the RNA. Several other...
    57 KB (7,094 words) - 23:56, 6 August 2024
  • Thumbnail for DCP1B
    mRNA-decapping enzyme 1B is a protein that in humans is encoded by the DCP1B gene. DCP1B is a core component of the mRNA decapping complex, a key factor...
    2 KB (282 words) - 09:03, 13 January 2022
  • hydrolase (EC 3.6.1.62, DCP2, NUDT16, D10 protein, D9 protein, D10 decapping enzyme, decapping enzyme) is an enzyme with systematic name m7GpppN-mRNA m7GDP...
    3 KB (369 words) - 05:06, 14 March 2025
  • Thumbnail for UPF1
    sapiens (human) ]". Lykke-Andersen J (2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol. Cell...
    12 KB (1,404 words) - 06:13, 28 September 2024
  • Thumbnail for EDC3
    Enhancer of mRNA-decapping protein 3 is a protein that in humans is encoded by the EDC3 gene. EDC3 is associated with an mRNA-decapping complex required for...
    7 KB (740 words) - 00:28, 29 March 2024
  • Thumbnail for Exosome complex
    LE (2003). "Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities". Molecular Cell. 12 (3):...
    43 KB (4,589 words) - 17:33, 6 November 2024
  • Thumbnail for TNRC6A
    Izaurralde E (2005). "A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing". RNA. 11 (11): 1640–1647. doi:10...
    10 KB (925 words) - 16:27, 28 October 2022
  • Thumbnail for UPF2
    PMID 15231747. Lykke-Andersen J (Dec 2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Molecular...
    11 KB (1,292 words) - 02:17, 24 December 2023
  • Thumbnail for Micropeptide
    enriches proteins associated with 5’ mRNA decapping. It is thought to interact directly with Enhancer of mRNA Decapping 4 (EDC4). ELABELA (ELA) (a.k.a. APELA)...
    31 KB (3,888 words) - 10:13, 5 December 2024
  • Thumbnail for UPF3A
    S2CID 389385. Lykke-Andersen J (2003). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol. Cell...
    9 KB (1,135 words) - 09:27, 17 August 2024
  • Thumbnail for Exonuclease
    normal turnover of mRNA: 5′ to 3′ exonuclease (Xrn1), which is a dependent decapping protein; 3′ to 5′ exonuclease, an independent protein; and poly(A)-specific...
    14 KB (1,758 words) - 03:31, 6 July 2025
  • Thumbnail for UPF3B
    PMID 14527413. Lykke-Andersen, Jens (Dec 2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol. Cell...
    9 KB (1,176 words) - 23:46, 4 September 2022
  • proposed to be the sites of mRNA degradation in the cell and involved in decapping and digestion of mRNAs earmarked for destruction. Later work called this...
    28 KB (2,093 words) - 18:17, 31 October 2024
  • miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes". Genes & Development. 20 (14): 1885–1898. doi:10.1101/gad.1424106...
    12 KB (1,061 words) - 14:20, 28 December 2024
  • mRNA Decapping”(1999) This paper examined promoters for decapping and how the promoters impede the translation and destruction of mRNA. “Decapping and...
    21 KB (2,487 words) - 03:48, 31 July 2024
  • Thumbnail for Poxviridae
    poxviruses have their enzymes for example vaccinia virus has decapping enzymes D9 and D10. Decapping enzymes that belong to the Nudix hydrolase superfamily...
    27 KB (3,008 words) - 01:35, 11 July 2025
  • Thumbnail for Integrated circuit packaging
    B-staging Potting (electronics) Quilt packaging Electronic packaging Decapping Rabaey, Jan (2007). Digital Integrated Circuits (2nd ed.). Prentice Hall...
    15 KB (1,590 words) - 06:50, 22 April 2025
  • attributed to the activity of decapping enzymes and Xrn1. Transcripts that enter the cytoplasm can be targeted by the Dcp1-Dcp2 complex which removes the 5' cap...
    18 KB (2,296 words) - 10:27, 5 January 2024
  • targets the RNA transcript for decay, facilitated by the non-canonical decapping enzyme, DXO. Considering the centrality of NAD in redox chemistry and...
    11 KB (1,600 words) - 16:19, 14 December 2024
  • Thumbnail for Gene expression
    bound by cap binding complex heterodimer (CBP20/CBP80), which aids in mRNA export to cytoplasm and also protect the RNA from decapping. Another modification...
    104 KB (11,629 words) - 20:59, 6 July 2025
  • Thumbnail for Centaur Technology
    Semiconductor, which is a joint venture co-owned by VIA. Unreleased CHA Processor Decapped CHA Processor Die shot of the CHA Processor Note: Even the 180 nm Duron...
    13 KB (1,283 words) - 00:39, 15 May 2025
  • Thumbnail for Chromosome 6
    polypeptide 2 (6p21.33) DHX16: DEAH-box helicase 16 (6p21.33) DOM3Z: Decapping exoribonuclease (6p21.33) DSP: Desmoplakin gene linked to cardiomyopathy...
    35 KB (2,403 words) - 20:59, 2 May 2025
  • Degradosome (category Protein complexes)
    nucleotidyltransferases (which add tails to transcripts), 5'-end capping and decapping enzymes and assorted RNA-binding proteins that help to model RNA for presentation...
    15 KB (1,889 words) - 04:29, 21 June 2024