Monoclonal immunoglobulin deposition disease, or MIDD, is a disease characterised by the deposition of monoclonal immunoglobulins on the basement membrane...

chain deposition disease (LCDD) is a rare blood cell disease which is characterized by deposition of fragments of infection-fighting immunoglobulins, called...

cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones...

deposits in the mesangium and glomerular basement membrane. Monoclonal immunoglobulin deposition disease (MIDD) involves light chains with unusual characteristics...

physician astute in new and evolving connective tissue diseases such as IgG4-RD. Serum immunoglobulin G4 (IGG4) is often elevated, but this is not always...

aggregate, the immunoglobulin level may be elevated with the disease, but the majority of such increased antibodies are of a monoclonal variety due to...

cryoglobulinemic disease, characterized on the monoclonal immunoglobulin(s) comprising the involved cryoglobulin, percentage of total cryoglobulinemic disease cases...

(also known as multiple myeloma) Plasmacytoma Monoclonal immunoglobulin deposition diseases Heavy chain diseases Extranodal marginal zone B cell lymphoma,...

plasmacytoma Monoclonal immunoglobulin deposition diseases Primary amyloidosis Light chain and heavy chain deposition diseases Extranodal marginal zone...

oligoclonal IgG bands in the cerebrospinal fluid and immunoglobulin as well as complement deposition on myelinated nerve fibers. Target antigens may also...

include such diseases as Creutzfeldt–Jakob disease (and a variant associated with mad cow disease) and other prion diseases, Alzheimer's disease, Parkinson's...

a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. The disease can be either localized...

Yokoo, Takashi; Shimizu, Akira (2019-01-15). "Monoclonal Immunoglobulin Deposition Disease and Related Diseases". Journal of Nippon Medical School. 86 (1):...

presence of monoclonal immunoglobulin is also done through immunofixation for detection of the monoclonal band. Presence of the monoclonal band would be...

"Intravenous Immunoglobulins (IVIGs) in Lupus Central Station, sourced from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National...

cyclophosphamide, low dose IL-2, intravenous immunoglobulins, and belimumab. Omalizumab is a monoclonal antibody that interacts with the binding site...

tests can be used to diagnose and monitor diseases like multiple myeloma and amyloidosis. Each immunoglobulin light-chain molecule contains approximately...

AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of...

[citation needed] Primary amyloidosis (AL) is caused by the deposition of excess immunoglobulin light chains which are secreted from plasma cells.[citation...

monoclonal gammopathy–skin changes syndrome (Crow–Fukase syndrome) Polyostotic fibrous dysplasia (Albright's disease) Popliteal pterygium...

reported. Infection induces the production of neutralizing homotypic immunoglobulin G (IgG) antibodies that provide lifelong immunity against the infecting...

affects bone deposition (osteoblasts). In inflammatory arthritis conditions such as rheumatoid arthritis, psoriatic arthritis, and Crohn's disease, proinflammatory...

with high-dose intravenous corticosteroids, monoclonal antibodies, cyclophosphamide, intravenous immunoglobulin (IVIG), or plasmapheresis. For skin involvement...

affecting the blood vessels caused by the deposition of abnormal proteins called cryoglobulins. These immunoglobulin proteins are soluble at normal body temperatures...

invasion of these tissues by plasma cells and/or the deposition of their circulating monoclonal immunoglobulin in them. Compared to multiple myeloma patients...

reaction with antibodies. All variants of immunoelectrophoresis require immunoglobulins, also known as antibodies, reacting with the proteins to be separated...

M9768/1 T-gamma lymphoproliferative disease M9769/1 Immunoglobulin deposition disease Systemic light chain disease Primary amyloidosis M9800/3 Leukemia...

(December 1996). "Protective effects of monoclonal antibody to VLA-4 on leukocyte adhesion and course of disease in adjuvant arthritis in rats". The Journal...

collagen deposition. The deposition then influences the airway remodelling in asthmatic patients. Besides its well-established role in respiratory diseases IL-13...

when taking natalizumab. While monoclonal antibodies are probably going to have some role in the treatment of the disease in the future, it is believed...