A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome...

A point accepted mutation — also known as a PAM — is the replacement of a single amino acid in the primary structure of a protein with another single...

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain...

In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a nonsense codon, or a premature stop codon in the transcribed...

germline mutation, or germinal mutation, is any detectable variation within germ cells (cells that, when fully developed, become sperm and ova). Mutations in...

be flipped. This mutation procedure, based on the biological point mutation, is called single point mutation. Other types of mutation operators are commonly...

In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid. It is...

A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number...

Silent mutations, also called synonymous or samesense mutations, are mutations in DNA that do not have an observable effect on the organism's phenotype...

sporadic single point nucleotide polymorphism c.1824 C>T (GGC -> GGT, p.Gly608Gly) in the gene that codes for matured Lamin A. This mutation activates a cryptic...

single type of mutation; there are many different types of mutations. Mutation rates are given for specific classes of mutations. Point mutations are a class...

mutations in this gene. Type I and Type II cancers (explained below) tend to have different mutations involved. ARID1A, which often carries a point mutation...

creates a point mutation converting the GCA codon to ACA. If the strand switch event is followed by a second round of DNA replication, the mutation may become...

nonsense mutations, where base alterations in the coding region code for a premature stop codon, producing a shorter final protein. Point mutations, or single...

number is used to differentiate individuals who have substitution mutations (point mutations) of the enzyme's gene, resulting in decreased enzyme function...

codons. A nonstop mutation, also called a stop-loss variant, is a point mutation that occurs within a stop codon. Nonstop mutations cause the continued...

are three types of point mutations; silent mutations, missense mutations and nonsense mutations. Silent mutations A silent mutation occurs when a change...

Transversion, in molecular biology, refers to a point mutation in DNA in which a single (two ring) purine (A or G) is changed for a (one ring) pyrimidine...

random mutations. Purging of deleterious alleles can be achieved on the population genetics level, with as little as a single point mutation being the...

analysis is a powerful technique in molecular biology for the detection of mutations, polymorphisms and epigenetic differences in double-stranded DNA samples...

this point mutation. This point mutation disrupts the mitochondrial gene for tRNA-Lys. This disrupts the synthesis of proteins. The remaining mutations only...

grape. It is a point genetic mutation of Pinot noir. Pinot noir is genetically unstable and will occasionally experience a point mutation in which a vine...

can withstand silence mutation rather than Missense or Nonsense point mutations at the third position. Since transition mutations (purine to purine or...

the body. It is an autosomal recessive disease resulting from various mutations of gene CYP19 (P450arom) which can lead to ambiguous genitalia and delayed...

normal nitrogen base into the complementary strand. Thus 5-BrU induces a point mutation via base substitution. This base pair will change from an A-T to a G-C...

form of the Hemingway (Hw) mutant the variation is induced by a single point mutation in a noncoding cis-regulatory element for SHH. In an extensive phenotypic...

a family with inherited pain insensitivity and identified a "novel point mutation in ZFHX2, encoding a putative transcription factor expressed in small...

Hemoglobin E (HbE) is an abnormal hemoglobin with a single point mutation in the β chain. At position 26 there is a change in the amino acid, from glutamic...

thousands of locations within an organism's genome. They have a higher mutation rate than other areas of DNA leading to high genetic diversity. Microsatellites...

is synonymous if a point mutation at that site would not change the amino acid, also known as a silent mutation. Because the mutation did not result in...