X chromosome reactivation (XCR) is the process by which the inactive X chromosome (the Xi) is re-activated in the cells of eutherian female mammals. Therian...

X-inactivation (also called Lyonization, after English geneticist Mary Lyon) is a process by which one of the copies of the X chromosome is inactivated...

genome targeting approaches such as base editing; and inactive X chromosome reactivation. Clinical trials Small molecule therapeutic development Approval...

pluripotency. One genetic marker is the expression of Sox2 and X chromosome reactivation, while epigenetic changes include the telomerase extending the...

biking event; see UCI race classifications § Mountain biking X-chromosome reactivation, in epigenetics Carian language, of ancient south-west Anatolia...

Barr) or X-chromatin is an inactive X chromosome. In species with XY sex-determination (including humans), females typically have two X chromosomes, and one...

Hughes Medical Institute Investigator. She is known for her work on X-chromosome inactivation and for discovering the functions of a new class of epigenetic...

(X-inactive specific transcript) is a non-coding RNA transcribed from the X chromosome of the placental mammals that acts as a major effector of the X-inactivation...

X chromosome inactivation. The name Tsix comes from the reverse of Xist, which stands for X-inactive specific transcript. Female mammals have two X chromosomes...

lacking of one X chromosome in females – i.e. X0 Triple X syndrome – an extra X chromosome in females Jacobs syndrome – an extra Y chromosome in males. The...

vitro, latent EBV in B cells can be reactivated by stimulating the B cell receptor, so it is likely reactivation in vivo takes place after latently infected...

section of genetic material is copied from one chromosome to another, without the donating chromosome being changed) (see SDSA – Synthesis Dependent Strand...

for an homologous prophage, a phenomenon termed prophage reactivation. Prophage reactivation in phage λ appears to occur by a recombinational repair process...

during 2011 discovered that reactivation can positively be triggered in vitro by histone deacetylase inhibitors. Once reactivation begins, the rolling circle...

MED12, is a human gene found on the X chromosome. Mutations in MED12 are responsible for at least two different forms of X-linked dominant mental retardation...

sequences associated with specialized proteins at the ends of linear chromosomes (see Sequences). Telomeres are a widespread genetic feature most commonly...

different genes: PPARα - chromosome 22q12-13.1 (OMIM 170998) PPARβ/δ - chromosome 6p21.2-21.1 (OMIM 600409) PPARγ - chromosome 3p25 (OMIM 601487). Hereditary...

X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 gene is located on chromosome 22 while...

meiosis that prevents the separation of the duplicated chromosomes (anaphase) until each chromosome is properly attached to the spindle. To achieve proper...

plasma membrane glycoprotein encoded by the IGSF1 gene, which maps to the X chromosome in humans and other mammalian species. IGSF1's function in normal cells...

Luria (1984, pg. 97) the discovery of reactivation of irradiated virus (referred to as "multiplicity reactivation") immediately started a flurry of activity...

to treat chronic myelogenous leukemia (CML) which has the Philadelphia chromosome. It may be used both in initial cases of chronic phase CML as well as...

responsible for a minor role in reactivation, whilst MTRR remains a major contributor in this reductive reactivation. Biological processes influenced...

of the chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes. The fruit...

vivo TERT deficient mouse model, reactivation of the TERT gene in quiescent populations in multiple organs reactivated telomerase and restored the cells’...

a key role in reactivation of the dormant virus. Changes in the immune system during menstruation may play a role in HSV-1 reactivation. Concurrent infections...

helicases (involved in RNA synthesis) DDX3X (found on the x chromosome) and DDX3Y (found on the y chromosome) lead to MYC oncogenesis in Burkitt lymphoma. Early...

replication of bacterial and plasmid chromosomes". Molecular Microbiology. 31 (6): 1611–8. doi:10.1046/j.1365-2958.1999.01287.x. PMID 10209736. S2CID 33177098...

potency-state comparison, MLL1 inhibition was also shown to reactivate the silenced X-chromosome which is typically deactivated in post-implantation epiblast...

microtubule-dependent processes: nuclear movement prior to anaphase, and chromosome separation. CDC20, along with a handful of other Cdc proteins, was discovered...